Derivados de Purinas e Pirimidinas

<p>Stability Hygroscopic<br>Applications A Serotonin 5HTID-receptor agonist.<br>References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>

<p>Applications A fluorescent analog of Nicotinamide Adenine Dinucleotide as a coenzyme for glutamate dehydrogenase.<br>References Gafni, A., et al.: Biochemistry, 20, 6041 (1981), Creedon, K., et al.: J. Biol. Chem., 269, 16364 (1994), Seley, K., et al.: Bioorg. Med. Chem., 6, 797 (1998),<br></p>

<p>Applications Lablled Caffeine (C080100). Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>

<p>Applications 6-Methylpurine (cas# 2004-03-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An analog of Thyroxine (L425600) with stimulatory effects on human red blood cell membrane Ca2+-activated ATPase. It is a potential inactivator of iodothyronine deiodinase type II.<br>References Davis, F.B. et al.: J. Biol. Chem., 258, 12373 (1983); Safran, M. et al.: J. Biol. Chem., 268, 14224 (1993);<br></p>

<p>Stability Very Hygroscopic<br>Applications Ethyl-(S)-(+)-Clopidogrel Sulfate is an analogue of S-(+)-Clopidogrel Hydrogen Sulfate (C587250) which is used as an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>