Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65562 produtos de "Derivados de Quinazolina e Quinolina"
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N- Hydro Ranitidine
CAS:Produto Controlado<p>Impurity Ranitidine EP Impurity B<br>Applications 2-[[5-(Dimethylaminomethyl)-2-furanyl]methylthio]ethylamine (Ranitidine EP Impurity B) is an impurity of Ranitidine (R120000).<br>References Evans, M., et al.: J. Pharm. Biomed. Anal., 7, 1 (1989), Plumb, R., et al.: Analyst., 130, 844 (2005),<br></p>Fórmula:C10H18N2OSCor e Forma:NeatPeso molecular:214.33Genfatinib-d3 (Imatinib-d3)
CAS:Produto Controlado<p>Applications Genfatinib-d3 (Imatinib-d3) is the labeled analogue of Genfatinib, a treatment of chronic myeloid leukemia (CML). It is a COVID19-related research product.<br>References Helmann, R., et. al.: J. Clin. Oncol., 32, 415 (2014)<br></p>Fórmula:C29D3H28N7OCor e Forma:NeatPeso molecular:496.624-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide
CAS:Pureza:99.0%Cor e Forma:SolidPeso molecular:482.82000732421875Ref: 10-F361865
1gA consultar5gA consultar10gA consultar25gA consultar10mgA consultar50mgA consultar100mgA consultar250mgA consultar500mgA consultarRef: 10-F469059
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar4-(2,4-Difluorobenzoyl)piperidine Hydrochloride
CAS:Produto Controlado<p>Applications Risperidone intermediate.<br></p>Fórmula:C12H13F2NO·ClHCor e Forma:NeatPeso molecular:261.69554-(2-Keto-1-benzimidazolinyl)piperidine
CAS:Produto Controlado<p>Applications 4-(2-Keto-1-benzimidazolinyl)piperidine is an impurity of Pimozide (P447800). Pimozide impurity A.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andersson, L., et al.: J. Lipid Res., 36, 1392 (1995), Andersson, M., et al.: J. Biol. Chem., 2005, 280, 27578 (2005),<br></p>Fórmula:C12H15N3OCor e Forma:WhitePeso molecular:217.27Mosapride
CAS:Produto Controlado<p>Applications A selective 5-HT4 receptor agonist. Gastroprokinetic.<br>References Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989), Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993), Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),<br></p>Fórmula:C21H25ClFN3O3Cor e Forma:Off White SolidPeso molecular:421.89Iprodione
CAS:<p>Applications Fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lacroix, L., et al.: Phytiatr.-Phytopharm., 23, 165 (1974), Brenneman, T.B., et al.: Plant Dis., 71, 546 (1987),<br></p>Fórmula:C13H13Cl2N3O3Cor e Forma:NeatPeso molecular:330.1710,11-Dihydro-11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepin-11-ol
CAS:Produto Controlado<p>Applications Quetol is an impurity of Quetiapine(Q509900) a dibenzothiazepine antipsychotic commonly used as monotherapy for patients with major depressive disorder and schizophrenia.<br>References Cutler, A., et al.: J. Clin. Psych., 70, 526 (2009); Kapur, S., et al.: Arch. Gen. Psych., 57, 553 (2000); Peuskens, J. & Link, C.: Acta. Psych. Scand., 96, 265 (1997)<br></p>Fórmula:C21H27N3O3SCor e Forma:YellowPeso molecular:401.5227-chloro-8-methyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:298.730010986328110H-Phenothiazine 5-Oxide
CAS:<p>Applications 10H-Phenothiazine 5-Oxide is a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.<br>References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010)<br></p>Fórmula:C12H9NOSCor e Forma:Light Beige To Light BrownPeso molecular:215.276-Amino-1,3-dimethyluracil
CAS:Produto Controlado<p>Applications 6-Amino-1,3-dimethyluracil is used as a reagent in the synthesis of new pyrimidine and caffeine derivatives that display highly potential antitumor activity. It is also used as a starting material in the synthesis of fused pyrido-pyrimidines.<br>References Abu-Hashem, A., et al.: Lett. Drug. Des. Discov., 12, 471 (2015); Azev, Y., et al.: Mendeleev Commun., 25, 310 (2015)<br></p>Fórmula:C6H9N3O2Cor e Forma:Light YellowPeso molecular:155.15cis-Hydroxy Perhexiline(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications A metabolite of Perhexiline.<br>References Shah, R., et al.: Br. Med. J., 284, 295 (1982), Gould, B., et al.: Xenobiotica, 16, 491 (1986), Marquet, P., et al.: Ther. Drug Monit., 24, 255 (2002), Sallustio, B., et al.: Br. J. Clin. Pharmacol., 54, 107 (2002),<br></p>Fórmula:C19H35NOCor e Forma:NeatPeso molecular:293.49(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS:Produto Controlado<p>Applications (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate used to prepare dipeptidyl peptidase IV (DPP-IV) inhibitors.<br>References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012); Sakashita, H., et al.: Bioorg. Med. Chem., 15, 641 (2007)<br></p>Fórmula:C13H20N2O4SCor e Forma:NeatPeso molecular:300.375,6,7,8-Tetradehydro Risperidone
CAS:Produto Controlado<p>Applications 5,6,7,8-Tetradehydro Risperidone is an impurity of risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C23H23FN4O2Cor e Forma:NeatPeso molecular:406.454-(Methylsulfonyl)phenylacetic Acid
CAS:Produto Controlado<p>Applications 4-(Methylsulfonyl)phenylacetic Acid is an intermediate used to prepare heterocyclic diaryl compounds as selective COX-2 inhibitors. It is also used to synthesize hydroxyfuranones as antioxidants and antiinflammatory agents.<br>References Eren, G., et al.: Bioorg. Med. Chem., 18, 6467 (2010); Weber, V., et al.: Bioorg. Med. Chem., 13, 4552 (2005)<br></p>Fórmula:C9H10O4SCor e Forma:NeatPeso molecular:214.24rac-Monepantel
CAS:Produto Controlado<p>Applications rac-Monepantel is a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Fórmula:C20H13F6N3O2SCor e Forma:Off White SolidPeso molecular:473.394-Diphenylmethoxypiperidine hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>Fórmula:C18H21NO·ClHCor e Forma:WhitePeso molecular:303.833-(1-Methanesulfonyl-3,5-dimethyl-1 H -pyrazol-4-yl)-propionic acid ethyl ester
CAS:Fórmula:C11H18N2O4SPureza:97%Cor e Forma:SolidPeso molecular:274.345-(2-Hydroxybenzoyl)-2-oxo-1-(1,3-thiazol-2-yl)-1,2-dihydropyridine-3-carbonitrile
CAS:Pureza:97%Peso molecular:323.3299865722656N-pyridin-3-yl-2-(tetrahydro-2H-pyran-4-ylcarbonyl)hydrazinecarbothioamide
Peso molecular:280.3500061035156TERT-BUTYL 3-(THIOPHEN-2-YL)PYRROLIDINE-1-CARBOXYLATE
CAS:Pureza:95.0%Peso molecular:253.36000061035156Ref: 10-F530586
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar5-(4-Trifluoromethyl-phenyl)-thiophene-2-carbaldehyde
CAS:Fórmula:C12H7F3OSPureza:95.0%Cor e Forma:SolidPeso molecular:256.246-Methyl-5-((3-(2-(methylthio)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-amine
CAS:Pureza:98%Peso molecular:374.45999145507813-(1-Pyridin-4-yl-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid
CAS:Pureza:90.0%Peso molecular:282.34298706054695-chloro-2-(1H-pyrazol-5-yl)aniline
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:193.63000488281252-[2-(pyridin-4-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:273.7600097656258-(4-Isopropylpyridin-2-yl)-2-methylbenzofuro[2,3-b]pyridine
CAS:Pureza:97%Peso molecular:302.377014160156258-propyl-4-(pyridine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:333.38800048828125Thiophene, 2,2′,2′′,2′′′-(1,2-ethenediylidene)tetrakis-
CAS:Pureza:98%Peso molecular:356.53Di-tert-butyl 1,4-dioxo-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate
CAS:Pureza:95%Peso molecular:500.57998657226562-(Pyridin-3-yl)-1H-benzo[d]imidazole
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:195.225006103515624-methyl-2-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)aniline
CAS:Pureza:95.0%Peso molecular:252.276992797851562-(2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:293.32199096679696-fluoro-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:259.299987792968754-[3-(methoxycarbonyl)-5-(thiophen-2-yl)-1H-pyrazol-1-yl]benzoic acid
CAS:Pureza:95.0%Peso molecular:328.33999633789061-(4-Pyridyl)-1,2,3,4-tetrahydro isoquinoline
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:210.27999877929688Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:95.0%Peso molecular:367.39999389648445-Chloro-3-(4-chloro-phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS:Pureza:95.0%Peso molecular:317.1700134277344(2E)-1-(1H-1,2,3-Benzotriazol-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS:Peso molecular:255.30000305175786-methoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:271.33999633789067-(1-ethyl-5-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:271.2799987792969Teneligliptin
CAS:<p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>Fórmula:C22H30N6OSPureza:99.73%Cor e Forma:SolidPeso molecular:426.5810-(Pyridin-3-yl)-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11(5H)-one
CAS:Pureza:98%Peso molecular:318.37600708007816-chloro-2-(4-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.7399902343756-Pyrrolidin-1-ylpyridin-3-amine
CAS:Fórmula:C9H13N3Pureza:95%Cor e Forma:SolidPeso molecular:163.2245-(Benzo[1,3]-dioxol-5yl)-picolinic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:243.218002319335942-((3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)aniline
CAS:Pureza:95.0%Peso molecular:252.27699279785156ETHYL 2-(3-METHYL-4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)ACETATE
CAS:Pureza:95.0%Peso molecular:246.26600646972656Ref: 10-F505729
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar5-(CHLOROMETHYL)-3-(3-PHENOXYPYRIDIN-4-YL)-1,2,4-OXADIAZOLE
Pureza:95.0%Peso molecular:287.700012207031253-phenyl-6-thien-2-ylisoxazolo[5,4-b]pyridine-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:322.33999633789067-CHLORO-5-METHYL-2-(2-(QUINOLIN-2-YL)ETHYL)-2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-1,6(5H)-DIONE
CAS:Pureza:95.0%Peso molecular:353.809997558593755-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
CAS:Pureza:97.0%Peso molecular:473.89001464843754-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
CAS:Pureza:98%Peso molecular:361.4890136718754-(pyridine-3-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:290.3190002441406
![10,11-Dihydro-11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepin-11-ol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FQ510033.webp&w=3840&q=75)
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![Di-tert-butyl 1,4-dioxo-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF695444.webp&w=3840&q=75)
![[1-(Quinazolin-4-yl)piperidin-4-yl]methanamine dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF091311.webp&w=3840&q=75)
![2-(Pyridin-3-yl)-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF238900.webp&w=3840&q=75)
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![4-[3-(methoxycarbonyl)-5-(thiophen-2-yl)-1H-pyrazol-1-yl]benzoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF526176.webp&w=3840&q=75)
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