Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65495 produtos de "Derivados de Quinazolina e Quinolina"
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2-Methoxy-5-(morpholine-4-sulfonyl)-benzoic acid
CAS:Fórmula:C12H15NO6SCor e Forma:SolidPeso molecular:301.31Sulindac
CAS:Produto Controlado<p>Applications Sulindac is a non-steroidal anti-inflammatory drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bjorkman., et al.: Am. J. Med., 105, 17S (1998), Thakur, et al.: Am. J. Hypertens., 12, 925 (1999),<br></p>Fórmula:C20H17FO3SCor e Forma:Yellow To Dark OrangePeso molecular:356.412-(4-(Methylsulfonamido)phenoxy)acetic Acid
CAS:Produto Controlado<p>Applications 2-(4-(Methylsulfonamido)phenoxy)acetic Acid is a metabolite of antiarrhythmic drug Dofetilide (D525700), which is a is a potassium channel blocker.<br>References Smith, D., et al.: Xenobiotica, 22, 709 (1992); Carmeliet, D., et al.: J. Pharmacol. Exp. Ther., 262, 809 (1992); Walker, D., et al.: Drug Metab. Dispos., 24, 447 (1996); Norgaard, B.L., et al.: Am. Heart J., 137, 1062 (1999); Torp-Pedersen, C., et al.: N. Engl. J. Med. 341, 857 (1999);<br></p>Fórmula:C9H11NO5SCor e Forma:NeatPeso molecular:245.25Tadalafil Ketolactam (>90%)
CAS:Produto Controlado<p>Stability Hygroscopic, Unstable in Solution<br>Applications Tadalafil Ketolactam is a Tadalafil (T004500) impurity.<br></p>Fórmula:C22H19N3O6Pureza:>90%Cor e Forma:NeatPeso molecular:421.40285-(6-Methoxynaphthalen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:268.2720031738281Chlorpromazine Sulfoxide
CAS:<p>Impurity Chlorpromazine EP Impurity A<br>Applications Chlorpromazine Sulfoxide is a derivative of Chlorpromazine Hydrochloride (C424750), which is a dopamine antagonist of the typical antipsychotic class of medications possessing additional antiadrenergic, antiserotonergic, anticholinergic and antihistaminergic properties used for schizophrenia treatment.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990), Yuhas, D., Svi. Smer. Mind, (March 2003),<br></p>Fórmula:C17H19ClN2OSCor e Forma:Light YellowPeso molecular:334.866,7,8,9-Tetrahydro Carvedilol
CAS:Produto Controlado<p>Applications Carvedilol (C184625) derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C24H30N2O4Cor e Forma:NeatPeso molecular:410.51Imazamox
CAS:Produto Controlado<p>Applications Imazamox is an imidazolinone based acetolactate synthase inhibitor that is utilized as a herbicide for weed control.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Riar, D.S., et al.: Int. J. Agron., 8 (2012); Grey, T.L., et al.: Weed. Technol., 26, 405 (2012); Rousonelos, S.L., et al.: Weed. Sci., 60, 335 (2012);<br></p>Fórmula:C15H19N3O4Cor e Forma:WhitePeso molecular:305.332-(4-Methoxyphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:279.2950134277344Propiconazole
CAS:Produto Controlado<p>Applications Propiconazole is a systemic foliar fungicide. Agricultural fungicide. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Child, R., et al.: Plant Growth Regul., 13, 203 (1993), Jaleel, C., et al.: Plant Sci., 171, 271 (2006), Jaleel, C., et al.: Pestic Biochem. Physiol., 91, 170 (2008),<br></p>Fórmula:C15H17Cl2N3O2Cor e Forma:YellowPeso molecular:342.222-(3-(pyridin-4-yl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethan-1-amine
CAS:Pureza:95.0%Peso molecular:242.3260040283203L-Valine Methyl Ester Hydrochloride
CAS:Produto Controlado<p>Applications L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.<br>References McClean, K. et al.: Tetrahedron Lett., 52, 215 (2011); Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992), Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),<br></p>Fórmula:C6H13NO2·ClHCor e Forma:NeatPeso molecular:167.632-(2-chlorophenyl)-8-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.7399902343751-(4-Chloro-phenyl)-3-(4-methylsulfanyl-phenyl)-1H-pyrazole-5-carboxylic acid
CAS:Peso molecular:344.80999755859375Hydantoin
CAS:Produto Controlado<p>Applications Hydantoin (cas# 461-72-3) is a compound useful in organic synthesis.<br></p>Fórmula:C3H4N2O2Cor e Forma:NeatPeso molecular:100.08N-Methyl-3,3-diphenylpropylamine
CAS:<p>Applications N-Methyl-3,3-diphenylpropylamine is an intermediate for the synthesis of SNRI-NMDA antagonist and neuroprotectants.<br>References Olney, J. et al.: Sci., 244, 1360 (1989); Williams, W., et al.: Mol. Pharmacol. 44, 851 (1993);<br></p>Fórmula:C16H19NCor e Forma:NeatPeso molecular:225.334-Cyanopyridine
CAS:Produto Controlado<p>Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.<br>References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)<br></p>Fórmula:C6H4N2Cor e Forma:WhitePeso molecular:104.11Ioversol
CAS:Produto Controlado<p>Applications Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium).<br>References Wilkins, R.A., et al.: Invest. Radiol., 24, 781 (1989), Kaufman, A.J., et al.: Urol. Radiol., 12, 56 (1990),<br></p>Fórmula:C18H24I3N3O9Cor e Forma:Off-WhitePeso molecular:807.111,3-Dimethyl Barbituric Acid
CAS:Produto Controlado<p>Applications 1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid (B118650). All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.<br>References Gupta, K., et al.: Eur. J. Med. Chem., 17, 448 (1982), Weber, L., et al.: Curr. Med. Chem., 9, 2085 (2002), Skiles, J., et al.: Curr. Med. Chem., 11, 2911 (2004),<br></p>Fórmula:C6H8N2O3Cor e Forma:NeatPeso molecular:156.14(E)-4-Hydroxy Tamoxifen O-β-D-Glucuronide
CAS:Produto Controlado<p>Applications A glucuronide of (Z)-4-Hydroxy Tamoxifen (or trans-4-hydroxytamoxifen), an active metabolite of Tamoxifen (T006000).<br>References Beaulieu, M., et al.: J. Biol. Chem., 271, 22855 (1996), Green, M., et al.: Drug Metab. Dispos., 26, 860 (1998), Nishiyama, T., et al.: Biochem. Pharmacol., 63, 1817 (2002),<br></p>Fórmula:C32H37NO8Pureza:>90%Cor e Forma:NeatPeso molecular:563.64(S)-9-Hydroxy Risperidone
CAS:Produto Controlado<p>Applications The S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Fórmula:C23H27FN4O3Cor e Forma:NeatPeso molecular:426.48Sitagliptin
CAS:Produto Controlado<p>Applications Sitagliptin (cas# 486460-32-6) is a useful research chemical.<br></p>Fórmula:C16H15F6N5OCor e Forma:Off-WhitePeso molecular:407.314-(2-fluorophenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:271.30999755859375DL-Fenfluramine Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications N-Ethyl-α-methyl-3-(trifluoromethyl)-benzeneethanamine hydrochloride has been used in case studies for the study of impulsivity, motor skills, and anxiogenic effects in the neuroscience community.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Whitney, K.N., et al.: Exp. Clin. Psychopharm., 21, 345-54 (2013); Arrant, A.E., et al.: Neuropharmacology, 65, 213-22 (2013)<br></p>Fórmula:C12H16F3N·ClHCor e Forma:WhitePeso molecular:267.72Benzocaine
CAS:Produto Controlado<p>Applications Benzocaine is used as an anesthetic (local).<br>References Kholod, Y., et al.: Environ. Sci. Technol., 43, 9208 (2009), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Perez-Garrido, Alfonso; Helguera, A., et al.: J. Pharm. Sci., 98, 4557 (2009), Onoue, S., et al.: J. Pharm. Sci., 98, 3647 (2009),<br></p>Fórmula:C9H11NO2Cor e Forma:NeatPeso molecular:165.191-(2,4,5-Trimethoxybenzyl)piperazine Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 1-(2,4,5-Trimethoxybenzyl)piperazine Dihydrochloride is an impurity of Trimetazidine (T795610). Trimetazidine impurity E.<br></p>Fórmula:C14H22N2O3·2ClHCor e Forma:NeatPeso molecular:339.26Ref: 10-F469403
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarRef: 10-F538267
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar2-(2,3-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:288.35998535156257-Desmethylagomelatine
CAS:Produto Controlado<p>Applications 7-Desmethylagomelatine, is a derivative of Agomelatine (A430000), a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression.Agomelatine Impurity 8<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),<br></p>Fórmula:C14H15NO2Cor e Forma:NeatPeso molecular:229.274-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine
CAS:<p>Applications 4-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine is an impurity of Mirtazapine (M365000). Mirtazapine impurity E.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Wynia, G., et al.: J. Chromatography, A 773, 339 (1997),<br></p>Fórmula:C17H21N3Cor e Forma:NeatPeso molecular:267.37N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitroquinazolin-4-yl)acetamide
CAS:Pureza:97.0%Peso molecular:390.7600097656252-Hydroxy-6-methyl-quinoline-4-carboxylic acid
CAS:Fórmula:C11H9NO3Pureza:95.0%Peso molecular:203.197Terfuboxon
CAS:Produto Controlado<p>Applications Terfuboxon is a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Fórmula:C9H21O3PS2Cor e Forma:NeatPeso molecular:272.367-chloro-4-methoxy-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:305.779998779296910,11-Dihydro-10-hydroxy Carbamazepine-D4 (Major)
CAS:Produto ControladoFórmula:C152H4H10N2O2Cor e Forma:BrownPeso molecular:258.314-Desmethyl-4-ethylimidazolyl Nilotinib
CAS:Produto ControladoFórmula:C29H24F3N7OCor e Forma:Light Beige To Light BrownPeso molecular:543.544-ethyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718755-(Benzyloxy)-1-(2,2-dimethoxyethyl)-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
CAS:Pureza:97.0%Peso molecular:391.3760070800781(S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
CAS:Pureza:95.0%Peso molecular:351.92999267578125Cerdulatinib hydrochloride
CAS:<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Fórmula:C20H28ClN7O3SPureza:99.85%Cor e Forma:SolidPeso molecular:482Desamino Chloroimiquimod
CAS:Produto Controlado<p>Impurity Imiquimod USP Related Compound C<br>Applications Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Fórmula:C14H14ClN3Cor e Forma:NeatPeso molecular:259.73Apixaban PG Ester-II
CAS:Produto Controlado<p>Applications Apixaban PG Ester-II is one of the multiple constituents extracted from Biebersteinia multifida, that exhibits inhibitory activity on acetylcholinesterase.<br>References Xiang, F., et al.: Faming Zhuanli Shenqing (2019), CN 109432093 A 20190308.<br></p>Fórmula:C28H30N4O6Cor e Forma:NeatPeso molecular:518.56Brimonidine
CAS:<p>M02627 - Brimonidine</p>Fórmula:C11H10BrN5Pureza:95%Cor e Forma:Solid, Yellow powderPeso molecular:292.1400146484375Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Produto Controlado<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Fórmula:C31H28N2OCor e Forma:NeatPeso molecular:444.57Norketamine-d4
CAS:Produto Controlado<p>Applications A labelled metabolite of Ketamine (K165300).<br>References Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973), Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977), Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005),<br></p>Fórmula:C12H10D4ClNOCor e Forma:NeatPeso molecular:227.72(R)-Tamsulosin-d4 Hydrochloride
CAS:Produto Controlado<p>Applications (R)-Tamsulosin-d4 Hydrochloride is the labeled analogue of (R)-Tamsulosin Hydrochloride (T006350), a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)<br></p>Fórmula:C20H25D4ClN2O5SCor e Forma:NeatPeso molecular:449.0Ambrisentan
CAS:Produto Controlado<p>Applications Nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Fórmula:C22H22N2O4Cor e Forma:Off-WhitePeso molecular:378.42Nimodipine-d7
CAS:Produto Controlado<p>Applications A labelled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral).<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Fórmula:C21H19D7N2O7Cor e Forma:NeatPeso molecular:425.481-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine (~10% inorganics)
CAS:Produto Controlado<p>Impurity Apremilast EP Impurity H<br>Applications 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H<br>References Ruchelman, A., et al.: Tetrahedron Asymmetr., 26, 553-559 (2015);<br></p>Fórmula:C12H19NO4SCor e Forma:NeatPeso molecular:273.35[5-(3-Thiophen-2-yl-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-carbamic acid tert-butyl ester
Pureza:95.0%Peso molecular:357.42999267578125[3-(3-pyridin-4-yl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]amine
CAS:Pureza:95.0%Peso molecular:288.31399536132811-(4-(Trifluoromethoxy)phenyl)-2-thiourea
CAS:Produto ControladoFórmula:C8H7F3N2OSCor e Forma:NeatPeso molecular:236.214’-Hydroxy Dutasteride
Produto Controlado<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C27H30F6N2O3Cor e Forma:NeatPeso molecular:544.53Domperidone
CAS:<p>Applications A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone (Motilium) is a dopamine blocker and an antidopaminergic reagent.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Fórmula:C22H24ClN5O2Cor e Forma:White To Off-WhitePeso molecular:425.911,2,3,4-Tetradehydro Argatroban
CAS:Produto Controlado<p>Applications 1,2,3,4-Tetrahydro Argatroban is a metabolite of Argatroban (A769000); a synthetic thrombin inhibitor and antithrombotic.<br>References Abiko, Y., et al.: Thromb. Res., 24, 285 (1981); Kikumoto, R., et al.: Biochemistry, 23, 85 (1984)<br></p>Fórmula:C23H32N6O5SCor e Forma:NeatPeso molecular:504.607-chloro-8-methyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:298.7300109863281trans-4-Aminocyclohexanol
CAS:<p>Applications trans-4-Aminocyclohexanol, used in the preparation of potential hypertensive agents and other biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chan, K.L. et al.: As. J. Pharmacol. Sci., 1, 91 (1979);<br></p>Fórmula:C6H13NOCor e Forma:NeatPeso molecular:115.174Gabapentin
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Gabapentin is an Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C9H17NO2Cor e Forma:NeatPeso molecular:171.24Vortioxetine Hydrobromide-D8
CAS:Produto Controlado<p>Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Fórmula:C18D8H14N2S·BrHCor e Forma:Off White PowderPeso molecular:387.4069Ondansetron-d3 Hydrochloride Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A labelled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000),<br></p>Fórmula:C18H16D3N3O•HClCor e Forma:NeatPeso molecular:296.393646Tulobuterol
CAS:Produto Controlado<p>Applications A sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750).<br>References Kubo, S., et al.: Arzneim.-Forsch., 25, 1028 (1975), Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 44, 361 (1993), Qureshi, S., et al.: J. Exp. Med., 189, 615 (1999),<br></p>Fórmula:C12H18ClNOCor e Forma:Off-WhitePeso molecular:227.738(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one (Mixture of Regioisomers)
CAS:Produto Controlado<p>Impurity Omeprazole EP Impurity F+Omeprazole EP Impurity G<br>Stability Sample unstable under MS condition<br>Applications 8(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one(Mixture of Regioisomers) (Omeprazole EP Impurity F+Omeprazole EP Impurity G) is a mixture of regioisomers of Omeprazole Impurity.<br>References Rackur, G., et al.: Biochem. Biophys. Res. Commmun., 128, 477 (1985),<br></p>Fórmula:C16H13N3O2SCor e Forma:NeatPeso molecular:311.3610,11-Dihydro-11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepin-11-ol
CAS:Produto Controlado<p>Applications Quetol is an impurity of Quetiapine(Q509900) a dibenzothiazepine antipsychotic commonly used as monotherapy for patients with major depressive disorder and schizophrenia.<br>References Cutler, A., et al.: J. Clin. Psych., 70, 526 (2009); Kapur, S., et al.: Arch. Gen. Psych., 57, 553 (2000); Peuskens, J. & Link, C.: Acta. Psych. Scand., 96, 265 (1997)<br></p>Fórmula:C21H27N3O3SCor e Forma:YellowPeso molecular:401.522Propylthiouracil N-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Applications Salt of Propylthiouracil N-β-D-Glucuronide (P838315), also a metabolite of Propylthiouracil (P838310).<br>References Lindsay, R. H., et al.: J. Pharm. Sci., 63 1383 (1974)Taurog, A., et al.: Endocrinology, 122, 592 (1988),<br></p>Fórmula:C13H17N2NaO7SCor e Forma:NeatPeso molecular:368.34Hydroxy Nefazodone Dihydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Nefazodone (N389100), an antidepressant.<br>References Barbhaiya, R., et al.: Eur. J. Clin. Pharmacol., 49, 221 (1995), Greene, D., et al.: Clin. Pharmacokinet., 33, 260 (1997), Kalgutkar, A., et al.: Drug Metab. Dispos., 33, 243 (2005),<br></p>Fórmula:C25H34Cl3N5O3Cor e Forma:NeatPeso molecular:558.93(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS:<p>Applications (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton's tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.<br>References Chen, W., et al.: PCT Int. Appl. (2011), WO 2011046964 A2 20110421<br></p>Fórmula:C22H22N6OCor e Forma:White To Light YellowPeso molecular:386.454-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
CAS:Produto Controlado<p>Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C23H27N3OCor e Forma:NeatPeso molecular:361.484,7-dimethoxy-N-(pyridin-2-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:301.35998535156252-(2',3-Dimethyl-[2,4'-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
CAS:Pureza:95.0%Peso molecular:396.4540100097656Ref: 10-F465541
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar(4-((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(4-(5-methyl-1H-pyrazol-1-yl)phenyl)methanone
CAS:Pureza:99.0%Peso molecular:512.9299926757812Ref: 10-F545254
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultarDronedarone Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008), Hoy, S., et al.: Drugs, 69, 1647 (2009), Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009),<br></p>Fórmula:C31H44N2O5S·ClHCor e Forma:NeatPeso molecular:593.222-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications 2-Hydroxypropyl Nortadalafil is a derivative of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005), Toomey, V. et al.: J. Pharm. Biomed. Anal., 59, 50 (2012);<br></p>Fórmula:C24H23N3O5Cor e Forma:NeatPeso molecular:433.46
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