Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65573 produtos de "Derivados de Quinazolina e Quinolina"
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4-Bromo-1-(2-fluoro-benzyl)-3-nitro-1H-pyrazole
CAS:Fórmula:C10H7BrFN3O2Pureza:97%Cor e Forma:SolidPeso molecular:300.087cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate
CAS:<p>Impurity Ketoconazole EP Impurity E<br>Applications cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate (Ketoconazole EP Impurity E) is an intermediate in the synthesis of the drug Ketoconazole (K186000).<br>References McManus, O., et al.: Biochemistry, 32, 6128 (1993), Olesen, S., et al.: Eur. J. Pharmacol., 251, 53 (1994), Assano, M., et al.: J. Pharm. Exp. Ther., 275, 775 (1995), Hewawasam, P., et al.: J. Med. Chem., 45, 1487 (2002),<br></p>Fórmula:C21H20Cl2N2O5SCor e Forma:NeatPeso molecular:483.36Imiquimod
CAS:Produto Controlado<p>Applications An immune response modifier. It stimulates the production of interferon-a.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998)<br></p>Fórmula:C14H16N4Cor e Forma:White To Off-WhitePeso molecular:240.308-tert-butyl-4-(thiophene-2-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:351.4599914550781Tenoxicam-d4
CAS:Produto Controlado<p>Applications Labelled Tenoxicam (T019500). Nonsteroidal anti-inflamatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),<br></p>Fórmula:C13D4H7N3O4S2Cor e Forma:Light YellowPeso molecular:341.3991-(1-Propyl-1H-pyrazol-4-yl)ethylamine
CAS:Fórmula:C8H15N3Pureza:97%Cor e Forma:SolidPeso molecular:153.229Amiodarone
CAS:<p>Amiodarone (Cordarone) is an antiarrhythmic compound that induces pulmonary toxicity and inhibits ATP-sensitive potassium channels.</p>Fórmula:C25H29I2NO3Pureza:98.09%Cor e Forma:Crystalline Powder; Crystals From Acetone SolidPeso molecular:645.311-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-1H-pyrazole-5-carboxylic acid
CAS:Peso molecular:377.61999511718753-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholinomethyl)-1,3,4,6-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one
CAS:Pureza:98.0%Peso molecular:487.2031107845-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione
CAS:Pureza:97.0%Peso molecular:370.4200134277344Ref: 10-F540283
1gA consultar2mg79,00€5mg128,00€10mg94,00€25mg120,00€50mg227,00€100mg412,00€250mgA consultar4-(furan-2-yl)-6-(5-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:257.309997558593756,7-Dimethoxy-2,3-dimethylquinoxaline
CAS:Pureza:95.0%Cor e Forma:Solid, Brown powderPeso molecular:218.255996704101563-(3,5-Dimethyl-pyrazol-1-yl)-benzoic acid
CAS:Fórmula:C12H12N2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:216.24Rizatriptan
CAS:<p>Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.</p>Fórmula:C15H19N5Pureza:99.74%Cor e Forma:SolidPeso molecular:269.354-(5-Amino-3-methylpyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester
CAS:Fórmula:C14H24N4O2Pureza:97%Cor e Forma:SolidPeso molecular:280.3726-chloro-2-(2-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.739990234375Dehydronitrosonisoldipine
CAS:Produto Controlado<p>Impurity Nisoldipine<br>Applications Dehydronitrosonisoldipine is an impurity of Nisoldipine (N489125). Nisoldipine is a dihydropyridine calcium channel blocker and it is antihypertensive and antianginal.<br>References Kazda, S., et al.: Arzneimittel-Forsch., 30, 2144 (1980); Pasanisi, F., et al.: Eur. J. Clin. Pharmacol., 29, 21 (1985); Lam, J., et al.: J. Am. Col. Cardiol., 6, 447 (1985)<br></p>Fórmula:C20H22N2O5Cor e Forma:NeatPeso molecular:370.42-((7-(5-(Di-p-tolylamino)thiophen-2-yl)benzo[c][1,2,5]thiadiazol-4-yl)methylene)malononitrile
CAS:Pureza:97%Peso molecular:489.61999511718752-(3-Aminophenyl)-quinoline-4-carboxylic acid
CAS:Pureza:97%Cor e Forma:SolidPeso molecular:264.28399658203125rac-Paroxetine-d4 Hydrochloride
CAS:Produto Controlado<p>Applications rac-Paroxetine-d4 Hydrochloride is a racemic labeled analogue of Paroxetine Hydrochloride (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978); Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982)<br></p>Fórmula:C19H17D4ClFNO3Cor e Forma:White To Light BrownPeso molecular:369.85rac-Epinephrine-3-O-sulfate
CAS:Fórmula:C9H13NO6SCor e Forma:White To Off-WhitePeso molecular:263.268Aripiprazole Hydrate
CAS:Produto Controlado<p>Applications Aripiprazole Hydrate is an agonist at the dopamine autoreceptor and an antagonist at the postsynaptic D2 receptor (1,2,3,4). Aripiprazole is an antipsychotic and a potential drug candidate for treating psychoses such as schizophrenia.<br>References Pan, B., et al.: Psychopharmacology, PagesAhead of Print( 2019), Kim, J. Y., et al.: Anticancer Res., 38, 5101 (2018)<br></p>Fórmula:C23H27Cl2N3O2·xH2OCor e Forma:NeatPeso molecular:448.39 + 36.022-((2S,3S)-3-(tert-Butyl)-4-methoxy-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine
CAS:Pureza:95.0%Peso molecular:301.32598876953125Rebamipide 3-Chloro Impurity (>80%)
CAS:Produto Controlado<p>Applications Rebamipide 3-Chloro Impurity (CAS# 90098-05-8) is a useful research chemical compound.<br></p>Fórmula:C19H15ClN2O4Pureza:>80%Cor e Forma:White To Off-WhitePeso molecular:370.78642-[1-Methyl-5-(trifluoromethyl)pyrazol-3-yl]-thiophene-5-carboxaldehyde
CAS:Fórmula:C10H7F3N2OSCor e Forma:SolidPeso molecular:260.233-AMINO-5-(TRIFLUOROMETHYL)PYRAZOLE HYDROCHLORIDE
CAS:Fórmula:C4H5ClF3N3Pureza:≥95%Cor e Forma:SolidPeso molecular:187.55Safinamide
CAS:<p>Safinamide: reversible MAO-B inhibitor, enhances dopamine, blocks glutamate release, sodium, calcium channels; may treat Parkinson's, RLS, epilepsy.</p>Fórmula:C17H19FN2O2Pureza:99.92%Cor e Forma:SolidPeso molecular:302.34Risperidone EP Impurity J
CAS:<p>Impurity Risperidone EP Impurity J<br>Applications 3-[2-[4-[(Z)-(4-Fluoro-2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)phenyl](hydroxyimino)methyl]piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity J) is a Risperidone (R525000) impurity.<br></p>Fórmula:C35H40F2N6O3Cor e Forma:White To YellowPeso molecular:630.7273Dexpramipexole
CAS:<p>Dexpramipexole ((R)-Pramipexole) is a mitochondrial protective agent that maintains mitochondrial function and energy production.</p>Fórmula:C10H17N3SPureza:99.78%Cor e Forma:SolidPeso molecular:211.33Empagliflozin R/S-Furanose
CAS:<p>Applications Empagliflozin R/S-Furanose is a mixture of R and S isomers of Empagliflozin Furanose. Both are byproducts in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012); Wang, X., et al.: Org. Lett., 16, 4090 (2014);<br></p>Fórmula:C23H27ClO7Cor e Forma:White To Off-WhitePeso molecular:450.9092-Chloropyridine
CAS:Produto Controlado<p>Applications 2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during the decomposition of specific insecticides. 2-CPY was found to be genotoxic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Demsia, G., et al.: Mutat. Res., 634, 32 (2007), Stapleton, D., et al.: Water Res., 43, 3964 (2009),<br></p>Fórmula:C5H4ClNCor e Forma:NeatPeso molecular:113.544-fluoro-2-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)aniline
CAS:Pureza:95.0%Peso molecular:256.239990234375Des [3-(1-Dimethylamino)ethyl] 3-Acetyl Rivastigmine
CAS:Produto Controlado<p>Impurity Rivastigmine EP Impurity C; USP Related Compound D<br>Applications Des [3-(1-dimethylamino)ethyl] 3-acetyl Rivastigmine (Rivastigmine EP Impurity C) is a derivative of Rivastigmine (Tartrate: R541000), and acetylcholinesterase inhibitor that is commonly used to treat dementia associated with Parkinson’s disease and Alzheimer’s disease.<br>References Emre, M., et al.: New. Engl. J. Med., 351, 2509 (2004); Polinsky, R.: Clin. Ther., 20, 634 (1998); Wilkinson, D., et al.: Int. J. Clin. Pract., 56, 441 (2001)<br></p>Fórmula:C12H15NO3Cor e Forma:Off-WhitePeso molecular:221.25Hydroxy-2-phenylpropyl Carbamate
CAS:Produto Controlado<p>Applications Hydroxy-2-phenylpropyl Carbamate is an impurity in the synthesis of Felbamate (F231000), an antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Fórmula:C10H13NO3Cor e Forma:NeatPeso molecular:195.22Acetohydrazide
CAS:Produto Controlado<p>Applications Acetohydrazide is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metushi, I.G., et al.: Chem. Res. Toxciol., 25, 2567 (2012); Fukino, K., et al.: J. Toxicol. Sci., 33, 667 (2008);<br></p>Fórmula:C2H6N2OCor e Forma:Off-WhitePeso molecular:74.08Methyl 2-(4-aminophenyl)quinoline-4-carboxylate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:278.3110046386719Niclosamide Ethanolamine Salt
CAS:<p>Applications Niclosamide Ethanolamine Salt is an ethanolamine salt of Niclosamide (N395500), which is used as an anthelmintic drug (Cestodes)<br>References Loftsson, T., et al.: J. Pharm. Sci., 85, 1017 (1996), Malik, N., et al.: Anti. Cancer Drugs, 10, 767 (1999), El-Sayed, M., et al.: Pharm. Res., 18, 23 (2001),<br></p>Fórmula:C13H8Cl2N2O4·C2H7NOCor e Forma:Dark YellowPeso molecular:388.206-fluoro-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:259.29998779296875(S)-a,a-Diphenyl-3-pyrrolidineacetamide L-Tartrate
CAS:Produto ControladoFórmula:C18H20N2O·C4H6O6Cor e Forma:NeatPeso molecular:430.455-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:232.19500732421875N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine
CAS:Pureza:95.0%Peso molecular:461.88000488281255-(4-CHLOROPHENYL)-1-(2-METHOXYPHENYL)-1H-PYRAZOL-3(2H)-ONE
CAS:Pureza:95.0%Peso molecular:300.7399902343752-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-6-propylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:285.3070068359375N-Methyl-N,N-bis(2-pyridylethyl)amine
CAS:<p>Impurity Betahistine EP Impurity C (Free Base)<br>Applications N-Methyl-N,N-bis(2-pyridylethyl)amine is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes.<br>References Mautner, F.A. et al.: Inorg. Chim. Acta, 362, 4073 (2009);<br></p>Fórmula:C15H19N3Cor e Forma:NeatPeso molecular:241.332-(Pyridin-4-ylmethyl)-2,3-dihydro-1H-isoindole-1,3-dione dihydrate
CAS:Pureza:98.0%Peso molecular:274.27600097656254'-Formylbiphenyl-2-carbonitrile
CAS:Produto Controlado<p>Applications 4'-Formylbiphenyl-2-carbonitrile is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br>References Goossen, L.J., et al.: J. Org. Chem., 72, 7473 (2007);<br></p>Fórmula:C14H9NOCor e Forma:NeatPeso molecular:207.22742-(3,4-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:329.19000244140625(R)-Viloxazine Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications The (R)-isomer of Viloxazine (V312440). Antidepressant.<br>References Howe, R., et al.: J. Med. Chem., 19, 1074 (1976), Pinder, R.M., et al.: Drugs, 13, 401 (1977),<br></p>Fórmula:C13H19NO3•HClCor e Forma:NeatPeso molecular:237.293646Mizolastine
CAS:<p>Applications A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticaria.<br>References Simons, F.E.R.: Clin. Alp. Allergy, 29, 3 (1999); Brostoff, J. et al.: Allergy, 51, 251 (1996); Gensthaler, B.M.: Pharm. Zeit., 143, 228 (1998);<br></p>Fórmula:C24H25FN6OCor e Forma:NeatPeso molecular:432.496-Hydroxy Chlorzoxazone-d2
CAS:Produto Controlado<p>Applications 6-Hydroxy Chlorzoxazone-d2 is a labeled analogue of 6-Hydroxy Chlorzoxazone (H825120), A major metabolite of chlorzoxazone and formed by the actions of cytochrome P450IIE1.<br>References Twele, et al.: Arzneim.-Forsch., 32, 759 (1982); Peter, et al.: che. Res. Toxicol., 3, 566 (1990)<br></p>Fórmula:C7H2D2ClNO3Cor e Forma:White To BrownPeso molecular:187.588-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one
CAS:Produto Controlado<p>Impurity CLOZAPINE EP IMPURITY A<br>Stability Store in Freezer<br>Applications A useful intermediate for the preparation of pharmaceutical actives and fine chemicals. Antipsychotic drug.<br>References Venkat Rao, S., Arab. J. Chem., 13, 6040 (2020)<br></p>Fórmula:C13H9ClN2OCor e Forma:NeatPeso molecular:244.68Chloropretadalafil
CAS:<p>Applications An intermediate in the synthesis of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Fórmula:C22H19ClN2O5Cor e Forma:White To Light Orange ColourPeso molecular:426.85N-(2-(Phenylthio)phenyl)dibenzo[b,f][1,4]thiazepin-11-amine
CAS:Produto ControladoFórmula:C25H18N2S2Cor e Forma:NeatPeso molecular:410.551-(2,3-Dimethylphenyl)ethyl Chloride
CAS:Produto Controlado<p>Applications 1-(2,3-Dimethylphenyl)ethyl Chloride is an impurity of Medetomidine (M203250), an α2-Adrenergic agonist. Sedative; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Fórmula:C10H13ClCor e Forma:Clear Colourless To Dark BrownPeso molecular:168.662-{[4-methyl-5-(thiophen-2-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid
CAS:Pureza:95+%Peso molecular:255.3099976Methomyl
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Methomyl is a carbamate insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Armes, N., et al.: Bull. Entomol. Res., 86, 499 (1996); Shono, T., et al.: Pest. Biochem. Physiol., 75, 1 (2003)<br></p>Fórmula:C5H10N2O2SCor e Forma:ColourlessPeso molecular:162.213-Bromomethyl-thiophene-2-carboxylic acid methyl ester
CAS:Pureza:97.0%Cor e Forma:Solid, Light yellow solidPeso molecular:235.10000610351562Dichlorodenafil
CAS:Produto Controlado<p>Applications Dichlorodenafil is an unapproved Sildenafil (S435001) functions by inhibiting the phosphodiesterase type 5 enzyme (PDE-5).<br>References Kim, J.Y., et al.: Chem. Pharm. Bull., 61, 572 (2013)<br></p>Fórmula:C19H20Cl2N4O2Cor e Forma:SolidPeso molecular:407.296-METHYL-N1-(3-METHYL-1-(6-(METHYLAMINO)PYRIMIDIN-4-YL)-1H-PYRAZOL-5-YL)BENZENE-1,3-DIAMINE
CAS:Pureza:95.0%Peso molecular:309.377014160156254-(4-ethoxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione
CAS:Pureza:97%Peso molecular:298.35998535156254,7-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718754-Hydroxybenzhydrazide
CAS:Produto Controlado<p>Applications 4-Hydroxybenzhydrazide works as an indicator in the determination of carbohydrates. Tissue (liver) bounded 4-Hydroxybenzhydrazide, the acid-hydrolyzable side chain of Nifuroxazide (N458500) can be used as a marker to monitor it’s residue in chicken.<br>References Lever, M., et al.: Anal. Biochem., 139, 205 (1984); Rocco, M., et al.: Anal. Biochem., 377, 251 (2008); Gao, F., et al.: J. Sci. Food Agr., 93, 2172 (2013)<br></p>Fórmula:C7H8N2O2Cor e Forma:WhitePeso molecular:152.15
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