Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65495 produtos de "Derivados de Quinazolina e Quinolina"
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2-Chlorothiophene
CAS:Produto Controlado<p>Applications 2-Chlorothiophene (cas# 96-43-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C4H3ClSCor e Forma:NeatPeso molecular:118.582-Oxo-ivabradine Hydrochloride
CAS:Produto ControladoFórmula:C27H34N2O6·ClHCor e Forma:NeatPeso molecular:519.031-(1,3-Dimethyl-1H-pyrazol-4-yl)-4,4,4-trifluoro-butane-1,3-dione
CAS:Fórmula:C9H9F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:234.178Acalabrutinib
CAS:Produto Controlado<p>Applications Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).<br>References Byrd; et al. (2015). "Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia."; "AstraZeneca to buy Acerta for blood cancer drug". www.rsc.org. Chemistry World - Royal Society of Chemistry. Retrieved 24 December 2015.<br></p>Fórmula:C26H23N7O2Cor e Forma:NeatPeso molecular:465.51(S)-N-(1-Amino-1-oxobutan-2-yl)-4-chlorobutanamide
CAS:<p>Impurity Levetiracetam USP Related Compound A<br>Applications (S)-N-(1-Amino-1-oxobutan-2-yl)-4-chlorobutanamide is a related compound of Levetiracetam (L331500). Levetiracetam related compound A. Levetiracetam USP Related Compound A.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C8H15ClN2O2Cor e Forma:White To Off-WhitePeso molecular:206.675-(Imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS:Pureza:95.0%Peso molecular:250.26100158691406Ref: 10-F435175
1gA consultar5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar8-Hydroxy Loxapine
CAS:<p>Stability Light Sensitive<br>Applications The inactive metabolite of Loxapine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bradford, M., et al.: Anal. Biochem., 72, 248 (1976), Fitton, A., et al.: Drugs, 40, 722 (1990), Jann, M., et al.: Clin. Pharmacokinet., 24, 161 (1993), Jennison, T., et al.: J. Anal. Toxicol., 21, 73 (1997),<br></p>Fórmula:C18H18ClN3O2Cor e Forma:NeatPeso molecular:343.81N-Formyl Linagliptin
Produto Controlado<p>Stability Hygroscopic<br>Applications N-Formyl Linagliptin is a derivative of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Fórmula:C26H28N8O3Cor e Forma:NeatPeso molecular:500.558-chloro-2-(2-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.7399902343752-[5-fluoro-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:291.75TERT-BUTYL 4-(7-CHLOROQUINOLIN-4-YL)-4-CYANOPIPERIDINE-1-CARBOXYLATE
CAS:Pureza:95.0%Peso molecular:371.86999511718752-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-1-(6-methylpyridin-2-yl)ethan-1-one
CAS:Pureza:98%Peso molecular:252.27699279785156Desmethyl 5-Methoxycarbonyl Nintedanib (Nintedanib Impurity B)
<p>Applications Desmethyl 5-Methoxycarbonyl Nintedanib is an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C30H31N5O4Cor e Forma:NeatPeso molecular:525.6Demethyl Benzydamine Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OCor e Forma:Off White SolidPeso molecular:331.84Lumiracoxib
CAS:Produto Controlado<p>Applications Lumiracoxib is a selective cyclooxygenase-2-(COX-2) inhibitor and an anti-inflammatory agent (1,2,3,4).<br>References (1) Bitner, M., et al.: Int. J. Clin. Pract., 58, 340 (2004) (2) Packman, E., et al.: Headache, 45, 1163 (2005) (3) Rordorf, C.M., et al.: Clin. Pharmacokinet., 44. 1247 (2005) (4) Schnitzer, T.J., et al.: Curr. Med. Res. Opin., 21, 151 (2005)<br></p>Fórmula:C15H13ClFNO2Cor e Forma:NeatPeso molecular:293.724-((Chloromethyl)sulfonyl)morpholine
CAS:Fórmula:C5H10ClNO3SPureza:95.0%Cor e Forma:No data available.Peso molecular:199.65Olanzapine Pamoate Hydrate
CAS:Produto Controlado<p>Applications A new Olanzapine pamoate formulation of a second-generation antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, J., et al.: Arch. Gen. Psychiatry, 60, 553 (2003), Kahn, R., et al.: Lancet, 371, 1085 (2008), Lauriello, J., et al.: J. Clin. Psychiatry, 69, 790 (2008),<br></p>Fórmula:C23H16O6·C17H20N4S·H2OCor e Forma:NeatPeso molecular:718.82Ethyl 2-amino-4-(1,1'-biphenyl-4-yl)thiophene-3-carboxylate
CAS:Pureza:95.0%Peso molecular:323.41000366210946-chloro-2-(5-methyl-2-furyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:287.700012207031254-(thiophen-2-yl)-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid
CAS:Pureza:95.0%Peso molecular:249.2899932861328Bicalutamide Sulfide
CAS:Produto ControladoFórmula:C18H14F4N2O2SCor e Forma:WhitePeso molecular:398.374-ethoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:285.36999511718757-(4-Iodobutoxy)-3,4-dihydroquinolin-2-one
CAS:Produto Controlado<p>Impurity Aripiprazole Iodobutoxyquinoline Impurity<br>Applications An impurity in the synthesis of Aripiprazole (A771000). A degradation product in Aripiprazole tablets. Aripiprazole Iodobutoxyquinoline Impurity<br>References Shah, V., et al.: J. Pharm. Sci., et al.: 81, 309 (1992), Zuo, X., et al.: Chromatographia, 64, 387 (2006),<br></p>Fórmula:C13H16INO2Cor e Forma:Off-WhitePeso molecular:345.18Benzbromarone
CAS:Produto Controlado<p>Applications Benzbromarone is a uricosuric agent used in the treatment of gout and hyperuricemia. Studies show that use of Benzbromarone results in less complications than other uricosuric agent such as Allopurinol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heel, R.C. et al.: Drugs, 14, 349 (1977); Perez-Ruiz, F. et al.: Ann. Rheum. Dis., 57, 545 (1998);<br></p>Fórmula:C17H12Br2O3Cor e Forma:Off-WhitePeso molecular:424.08trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol
CAS:<p>Applications trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and a metabolite of Bromohexine.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Fórmula:C13H19BrN2OCor e Forma:NeatPeso molecular:299.212-(PYRIDIN-2-YLMETHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID
Pureza:90.0%Peso molecular:253.26100158691406Nuarimol
CAS:<p>Applications Nuarimol is used in the preparation of difluoroethyl-containing heterocyclic compounds useful as antiviral agents and fungicides. Also used as a substance in the modelling inhibition of avian aromatase by azole pesticides.<br>References Fan, Z., et al.: Faming Zhuanli Shenqing (2016), CN 105503708 A 20160420; Saxena, A. K., et al.: SAR and QSAR in Environmental Research, 26, 757 (2015)<br></p>Fórmula:C17H12ClFN2OCor e Forma:White To Light YellowPeso molecular:314.74Ambrisentan
CAS:Produto Controlado<p>Applications Nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Fórmula:C22H22N2O4Cor e Forma:Off-WhitePeso molecular:378.424-Chloro-1-(4-fluorophenyl)-3-methyl-1H-pyrazol-5-amine
CAS:Pureza:95%Peso molecular:225.649993896484383-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
CAS:Produto Controlado<p>Applications 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one (cas# 545445-44-1) is a useful research chemical.<br></p>Fórmula:C20H25O3N3Cor e Forma:BeigePeso molecular:355.431-Chloro Dihydro Dutasteride
CAS:<p>Impurity Dutasteride EP Impurity F<br>Applications 1-Chloro Dihydro Dutasteride (Dutateride EP Impurity F) is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride (D735000).<br></p>Fórmula:C27H31ClF6N2O2Cor e Forma:NeatPeso molecular:564.993-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Produto Controlado<p>Impurity Paliperidone USP Related Compound C<br>Applications Paliperidone USP Related Compound C<br></p>Fórmula:C11H15ClN2O2Cor e Forma:Light Yellow To BrownPeso molecular:242.705-(2,6-DIMETHOXYPHENYL)-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID
Pureza:90.0%Peso molecular:342.325988769531254-(4-(3-(1H-Pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)morpholine
CAS:Pureza:97.0%Peso molecular:346.3940124511719(4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS:Produto Controlado<p>Applications A HMG-CoA reductase inhibitor intermediate.<br>References Hummel, W., et al.: J. Microbiol. Methods, 9, 201 (1989), Jendralla, H., et al.: J. Med. Chem., 34, 2962 (1991), Vicenzi, J., et al.: Enzyme Microb. Technol., 20, 494 ( 1997),<br></p>Fórmula:C13H23ClO4Cor e Forma:NeatPeso molecular:278.77
![5-(Imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF435175.webp&w=3840&q=75)
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![2-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-1-(6-methylpyridin-2-yl)ethan-1-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF774950.webp&w=3840&q=75)
![4-(thiophen-2-yl)-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF522494.webp&w=3840&q=75)
![trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA601985.webp&w=3840&q=75)
![4-[2,3']Bipyridinyl-5-yl-pyrimidin-2-ylamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF511277.webp&w=3840&q=75)
![2-(PYRIDIN-2-YLMETHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF530713.webp&w=3840&q=75)
![3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC366270.webp&w=3840&q=75)
![4-(4-(3-(1H-Pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)morpholine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF540408.webp&w=3840&q=75)
