Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65541 produtos de "Derivados de Quinazolina e Quinolina"
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2-(3,4-Dimethoxy-phenyl)-quinoline-4-carboxylic acid hydrazide
CAS:Cor e Forma:SolidPeso molecular:323.351989746093752-(2,6-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:329.19000244140625Famotidine Related Compound A Dihydrochloride
CAS:Produto ControladoFórmula:C8H14N6S2ClHCor e Forma:NeatPeso molecular:331.293-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
CAS:Pureza:98%Peso molecular:649.630004882813Ref: 10-F867169
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar1-Isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide
CAS:Pureza:98%Cor e Forma:SolidPeso molecular:569.7540283203133,7-Dihydro-3,7-dimethyl-6-[(5-oxohexyl)oxy]-2H-purin-2-one
CAS:Fórmula:C13H18N4O3Cor e Forma:NeatPeso molecular:278.31Ref: 10-F214928
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarGabapentin-d6 Hydrochloride
CAS:Produto Controlado<p>Applications Gabapentin Hydrochloride is a salt analogue of Gabapentin-d6 (G117253), a labelled amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.O. et al.: Arzneim.-Forsch., 36, 830 (1986); Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C9H11D6NO2·HClCor e Forma:NeatPeso molecular:213.735-Nitro-1 H -pyrazole-3-carboxylic acid (2-amino-ethyl)-amide
CAS:Fórmula:C6H9N5O3Cor e Forma:SolidPeso molecular:199.17Mirtazapine-d3
CAS:Produto Controlado<p>Applications An α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Fórmula:C172H3H16N3Cor e Forma:White To BeigePeso molecular:268.372,2-Diphenylglycine
CAS:Produto Controlado<p>Impurity Phenytoin USP Related Compound A 2,2-Diphenylglycine<br>Stability Hygroscopic<br>Applications 2,2-Diphenylglycine (Phenytoin USP Related Compound A 2,2-Diphenylglycine) is a decomposition product of Phenytoin (D491650), which reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.<br>References Shah, V. et al.: J. Pharm. Sci., 75, 1113 (1986); Faucette, S., et al.: J. Pharmacol. Exp. Ther., 320, 72 (2007); Raymond, H. et al.: Teratol., 10, 237 (1974);<br></p>Fórmula:C14H13NO2Cor e Forma:White To Off-WhitePeso molecular:227.26Deferiprone-d3 3-O-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995);<br></p>Fórmula:C13H13D3NNaO8Cor e Forma:Off-White To Light BeigePeso molecular:340.28N-Ethyl-N-methyl-3-vinylphenyl Carbamate
CAS:Produto Controlado<p>Impurity Rivastigmine USP Related Compound F<br>Stability Light Sensitive<br>Applications A related compound of Rivastigmine (R541000), a cholinesterase inhibitor. Rivastigmine USP Related Compound F.<br></p>Fórmula:C12H15NO2Cor e Forma:White SolidPeso molecular:205.25L-Aminobutyric Acid
CAS:<p>Applications Receptor antagonist.<br>References Porter, D.J.T., et al.: Biochem. Pharmacol., 50, 1475 (1995),<br></p>Fórmula:C4H9NO2Cor e Forma:NeatPeso molecular:103.12N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide
CAS:Pureza:98%Peso molecular:302.760009765625N-Nitroso Desmethyl Rizatriptan
Produto ControladoFórmula:C14H16N6OCor e Forma:NeatPeso molecular:284.316Intedanib
CAS:Produto Controlado<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C31H33N5O4Cor e Forma:NeatPeso molecular:539.621,3,5-trimethyl-1H-pyrazole-4-carbonyl chloride
CAS:Fórmula:C7H9ClN2OPureza:95.0%Cor e Forma:SolidPeso molecular:172.61Desmethyl Levofloxacin Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Levofloxacin.<br>References Sudo, K., et al.: Xenobiotica, 16, 72 (1986), Wong, F., et al.: Drug Metab. Dispos., 18, 1103 (1990), Aminimanizani, A., et al.: J. Clin. Pharmacokinet., 40, 169 (2001), Athamna, A., et al.: J. Antimicrob. Chemother., 53, 247 (2004), Tanaka, M., et al.: J. Pharmacol., 56, 463 (2004),<br></p>Fórmula:C17H18FN3O4•HClCor e Forma:NeatPeso molecular:347.343646Pomalidomide-(d4 major)
CAS:Produto Controlado<p>Applications Pomalidomide-d4 is the labeled anaxlogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.<br>References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Fórmula:C13H7D4N3O4Cor e Forma:NeatPeso molecular:277.27N-Desmethyl-N-cyclopentyl Tadalafil
CAS:Produto Controlado<p>Applications N-Desmethyl-N-cyclopentyl Tadalafil is used as a reagent to synthesize tetracyclic cGMP-specific phosphodiesterase inhibitors, compounds that have potential to treat cardiovascular disorders and erectile dysfunction.<br>References Daugan, A. & Gellibert, F. Tetracyclic cGMP-specific Phosphodiesterase Inhibitors and Their Use in Disease Treatment. U.S. 6143746. Nov 7, 2000<br></p>Fórmula:C26H25N3O4Cor e Forma:NeatPeso molecular:443.492-Phenylphenol
CAS:<p>Applications 2-Phenylphenol is an agricultural fungicide and is no longer used as a food additive (1). It has been associated with the incidence of bladder cancer in male rats which may be related to its primary metabolite, phenylhydroquinone (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gouin T. et al.: Environ Pollut. 2012 Jun;165:208-14. 2. Balakrishnan, S. et al.: Environ Mol Mutagen. 2016 Apr;57(3):210-9<br></p>Fórmula:C12H10OCor e Forma:Light PinkPeso molecular:170.21Methyl 5-hydroxymethyl-1-methyl-1H-pyrazole-3-carboxylate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:170.16799926757812Ref: 10-F316485
1gA consultar2gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultar500mgA consultar5-tert-Butyl-1-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid
CAS:Fórmula:C14H15N3O4Pureza:98%Cor e Forma:SolidPeso molecular:289.2912-(5-(Bromomethyl)pyridin-2-yl)isoindoline-1,3-dione
CAS:Pureza:95.0%Peso molecular:317.1419982910156Omeprazole-d3 Sulfide
CAS:Produto ControladoFórmula:C172H3H16N3O2SCor e Forma:NeatPeso molecular:332.44rac Rivastigmine-d6
CAS:Produto Controlado<p>Applications Labelled rac Rivastigmine. A brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Fórmula:C14H16D6N2O2Cor e Forma:NeatPeso molecular:256.374,7-dimethoxy-N-(pyridin-4-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:301.3599853515625Dutasteride β-Dimer
CAS:Produto Controlado<p>Applications Dutasteride β-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C46H55F6N3O4Cor e Forma:NeatPeso molecular:827.945-Benzyl Benzydamine Hydrochloride
CAS:<p>Applications 5-Benzyl Benzydamine is an impurity of Benzydamine hydrochloride (B209950). Benzydamine impurity B.<br></p>Fórmula:C26H29N3O·ClHCor e Forma:NeatPeso molecular:435.99Defluoro Levofloxacin
CAS:<p>Impurity Levofloxacin USP Related Compound F<br>Applications Nonfluorinated analog of Levofloxacin (L360000). Levofloxacin USP Related Compound F.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Fujita, M., et al.: Chem. Pharm. Bull., 44, 987 (1996), Graul, A., et al.: Drugs Future, 24, 1324 (1999), Takahata, M., et al.: Antimicrob. Agents Chemother., 43, 1077 (1999),<br></p>Fórmula:C18H21N3O4Cor e Forma:Off-WhitePeso molecular:343.382-Bromo-4,5-dimethoxybenzyl Alcohol
CAS:Produto Controlado<p>Applications 2-Bromo-4,5-dimethoxybenzyl Alcohol is an intermediate compound used for the synthetic preparation of pharmaceutical goods. 2-Bromo-4,5-dimethoxybenzyl Alcohol have been used in the synthesis of rotenoids.<br>References Feng, L.S., et al.: Euro. J. Med. Chem., 55, 125 (2012); Candito, D.A., et al.: J. Am. Chem. Soc., 134, 15572 (2012);<br></p>Fórmula:C9H11BrO3Cor e Forma:Off WhitePeso molecular:247.092-(4-Chlorophenoxy)aniline
CAS:Produto Controlado<p>Applications Amoxapine impurity.<br>References Matsuo, M., et al.: Chem. Pharma. Bull., 33, 4409 (1985),<br></p>Fórmula:C12H10ClNOCor e Forma:NeatPeso molecular:219.678-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide
CAS:Produto Controlado<p>Impurity Aripiprazole Impurity 12<br>Applications 8-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide is an intermediate used in the preparation of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Antipsychotic. Aripiprazole Impurity 12<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Fórmula:C14H19Cl2N2·BrCor e Forma:NeatPeso molecular:366.12Salbutamol Glyoxal Impurity
Produto Controlado<p>Stability Hygroscopic<br>Applications Salbutamol Glyoxal Impurity that is synthesized from C369215 (3-Chloromethyl-4-hydroxyacetophenone).<br></p>Fórmula:C9H10O5Cor e Forma:Off White SolidPeso molecular:198.17ent-Levobunolol Hydrochloride (R-Bunolol Hydrochloride)
CAS:Produto Controlado<p>Applications A non-selective ß-adrenoceptor antagonist used as an anticonvulsant. The enantiomer of Levobunolol (L335000).<br>References Kaplan, H.R., et al.: Eur. J. Pharm., 16, 237 (1971), DiCarlo,F.J., et al.: Clin. Pharm. Ther., 22, 858 (1977)<br></p>Fórmula:C17H25NO3·ClHCor e Forma:NeatPeso molecular:327.85
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