Derivados das Benzodiazepinas
As benzodiazepinas são compostos orgânicos com um núcleo bicíclico fundido de benzodiazepina, amplamente utilizadas no desenvolvimento de fármacos com propriedades ansiolíticas, sedativas, anticonvulsivantes e relaxantes musculares. Os seus derivados incluem estruturas modificadas que melhoram a seletividade e o perfil farmacocinético, permitindo a criação de novas moléculas com aplicações terapêuticas avançadas. Estes compostos são utilizados na formulação de APIs para o tratamento de distúrbios do sono, ansiedade, epilepsia e espasmos musculares. Além disso, os derivados das benzodiazepinas são essenciais na investigação de novos agentes psicotrópicos e na otimização de tratamentos neurológicos.
Na CymitQuimica, oferecemos derivados de benzodiazepinas de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e neurociência.
Foram encontrados 332 produtos de "Derivados das Benzodiazepinas"
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4-Boc-8-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19ClN2O2Pureza:97.0%Peso molecular:282.777,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C11H16N2O2Pureza:97.0%Peso molecular:208.2617-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE HCL
CAS:Fórmula:C9H12BrClN2Pureza:95.0%Peso molecular:263.568-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H11ClN2Pureza:97.0%Cor e Forma:SolidPeso molecular:182.652,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H12N2Pureza:97.0%Cor e Forma:White to yellow/orange crystalline powderPeso molecular:148.2098-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Fórmula:C9H9BrN2OPureza:97.0%Peso molecular:241.0884-Boc-7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C16H24N2O4Pureza:97.0%Peso molecular:308.3787-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C10H14N2Pureza:97.0%Cor e Forma:SolidPeso molecular:162.2364-Boc-7-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H20N2O3Pureza:97.0%Peso molecular:264.3251,2,4,5-Tetrahydro-benzo[e][1,4]diazepin-3-one
CAS:Fórmula:C9H10N2OPureza:97.0%Cor e Forma:SolidPeso molecular:162.1927-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS:Fórmula:C10H9FN2O2Pureza:97%Peso molecular:208.1927-AMINO-4-BOC-4,5-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
CAS:Fórmula:C14H19N3O3Pureza:97.0%Peso molecular:277.3242-(2-Aminoacetamido)-5-nitro-2'-chlorobenzophenone Hydrochloride (Clonazepam Impurity)
CAS:Produto ControladoFórmula:C15H12ClN3O4·ClHCor e Forma:WhitePeso molecular:370.1874N,N-Dimethylformamide Diethyl Acetal
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications N,N-Dimethylformamide Diethyl Acetal is used as a reagent in the design of EGF-R tyrosine kinase inhibitors. Also used in the synthesis of aminopyridine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Traxler, P. et al.: J. Med. Chem., 40, 3601 (1997); Cheikh, N. et al.: Tetrahedron, 69, 1234 (2013);<br></p>Fórmula:C7H17NO2Cor e Forma:NeatPeso molecular:147.223-Amino-4-(2-fluorophenyl)-1-methyl-6-nitroquinolin-2(1H)-one
CAS:Produto ControladoFórmula:C16H12FN3O3Cor e Forma:NeatPeso molecular:313.28N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide
CAS:Produto Controlado<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>Fórmula:C14H10BrClN2O2Cor e Forma:Light Yellow To BeigePeso molecular:353.602-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide
CAS:Produto Controlado<p>Applications 2-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>Fórmula:C14H10Br2N2O2Cor e Forma:NeatPeso molecular:398.05Alprazolam 5,6-Epoxide
CAS:Produto Controlado<p>Applications Alprazolam derivative.<br>References Hester, J. et al., J. of Med. Chem. 23, 643 (1980)<br></p>Fórmula:C17H13ClN4OCor e Forma:NeatPeso molecular:324.773-Amino-6-chloro-3,4-dihydro-2-methyl-4-phenyl-4-quinazolinol
CAS:Produto ControladoFórmula:C15H14ClN3OCor e Forma:NeatPeso molecular:287.742-Amino-5-nitrobenzophenone
CAS:Produto ControladoFórmula:C13H10N2O3Cor e Forma:NeatPeso molecular:242.23Flumazenil Carboxylic Acid-D3
Produto Controlado<p>Applications Flumazenil Carboxylic Acid-D3 is an isotope labelled form of Flumazenil Carboxylic Acid (F500455); a derivative of Flumazenil (F500455), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Fórmula:C13H7D3FN3O3Cor e Forma:NeatPeso molecular:278.257-Aminonorflunitrazepam
CAS:Produto ControladoFórmula:C15H12FN3OCor e Forma:Light YellowPeso molecular:269.272-(2-Acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine
CAS:Produto Controlado<p>Applications 2-(2-Acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine is an impurity of Alprazolam (A575650.<br>References Hester, J.B., et al.: J. Org. Chem., 44, 2688, (1979); Anjaneyulu, Y., et al.: Asian. J. Chem., 19, 3375 (2007);<br></p>Fórmula:C17H15ClN4OCor e Forma:White To Off-WhitePeso molecular:326.783-Methyl Clobazam
CAS:Produto Controlado<p>Applications 3-Methyl Clobazam is a metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C17H15ClN2O2Cor e Forma:NeatPeso molecular:314.77Clobazam CIV
CAS:Produto ControladoClobazam (inn) and methyprylon (inn)Fórmula:C16H13ClN2O2Cor e Forma:White Crystalline PowderPeso molecular:300.066562-(2-Amino-5-bromobenzoyl)pyridine
CAS:<p>2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval</p>Fórmula:C12H9BrN2OPureza:Min. 95%Peso molecular:277.12 g/molRef: 4Z-E-153009
Produto descontinuadoRef: 4Z-A-231026
Produto descontinuado7-Amino Clonazepam-d4
CAS:Produto Controlado<p>Applications A labelled major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Fórmula:C152H4H8ClN3OCor e Forma:NeatPeso molecular:289.75
![4-Boc-8-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF041119.webp&w=3840&q=75)
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![7-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE HCL](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF527266.webp&w=3840&q=75)
![8-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF040373.webp&w=3840&q=75)
![2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF040153.webp&w=3840&q=75)
![8-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF540304.webp&w=3840&q=75)
![4-Methyl-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF712698.webp&w=3840&q=75)
![4-Boc-7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF041213.webp&w=3840&q=75)
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![4-Boc-7-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF041024.webp&w=3840&q=75)
![1,2,4,5-Tetrahydro-benzo[e][1,4]diazepin-3-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF040224.webp&w=3840&q=75)
![7-AMINO-4-BOC-4,5-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF300729.webp&w=3840&q=75)
![2-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB680675.webp&w=3840&q=75)
