Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4949 produtos de "Esteroides e Derivados"
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1-Chloro Dihydro Dutasteride
CAS:<p>Impurity Dutasteride EP Impurity F<br>Applications 1-Chloro Dihydro Dutasteride (Dutateride EP Impurity F) is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride (D735000).<br></p>Fórmula:C27H31ClF6N2O2Cor e Forma:NeatPeso molecular:564.99(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione
CAS:Produto Controlado<p>Impurity Betamethasone EP Impurity C<br>Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.<br>References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)<br></p>Fórmula:C22H28O4Cor e Forma:NeatPeso molecular:356.469α-Bromodesonide ~90%
CAS:Produto Controlado<p>Applications 9α-Bromodesonide is a bromo derivative of Desonide (D296940); an anti-inflammatory agent.<br>References Phillips, et al.: Toxicol. Appl. Pharmacol., 20, 522 (1971); Sanen, F.J., et al.: Int. J. Clin. Pharmacol. Biopharm., 12, 174 (1975); Tarayre, J.P., et al.: Pharmacol., 19, 323 (1979)<br></p>Fórmula:C24H31BrO6Pureza:~90%Cor e Forma:YellowPeso molecular:495.4033Lathosterol
CAS:<p>Applications A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.<br>References Chyou, P., et al.: Age Ageing, 29, 69 (2000), Schatz, I., et al.: Lancet, 358, 351 (2001), Bjorkman, M., et al.: Eur. J. Endocrinol., 158, 749 (2008),<br></p>Fórmula:C27H46OCor e Forma:White To Off-WhitePeso molecular:386.653α-Hydroxy Tibolone
CAS:Produto Controlado<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),<br></p>Fórmula:C21H30O2Cor e Forma:White To Off-WhitePeso molecular:314.4616a-Methyl Prednisolone
CAS:Produto Controlado<p>Applications 16α-Methylprednisolone is the 16α-Methyl analogue of Prednisolone (P703740). 16α-Methylprednisolone is an anti-inflammatory corticosteroid.<br>References Biju, P. et al.: Bioorg. Med. Chem. Lett., 22, 1086 (2012); Dausse, J.P. et al.: Mol. Pharmacol., 13, 948 (1977):<br></p>Fórmula:C22H30O5Cor e Forma:NeatPeso molecular:374.47Clobetasol Propionate Impurity E
<p>Applications Clobetasol Propionate Impurity E is an impurity of Clobetasol (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H33ClO4Cor e Forma:NeatPeso molecular:432.984-Hydroxy-17β-estradiol
CAS:Produto Controlado<p>Applications A metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Fórmula:C18H24O3Cor e Forma:FluidPeso molecular:288.38Δ-5(10)-Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity B<br>Applications Δ-5(10)-Norethindrone Acetate (Norethindrone Acetate EP Impurity B) is a Norethindrone Acetate (N675990) impurity. Used in studies of progesterone-binding properties of purified uteroglobin-like protein.<br>References Beato, M. et al.: J. Reprod. Fert., 53, 305 (1978); Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975); Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979);<br></p>Fórmula:C22H28O3Cor e Forma:Off-WhitePeso molecular:340.46Betamethasone 21-O-Ethyl Carbonate
CAS:Produto Controlado<p>Impurity Betamethasone EP Impurity D<br>Applications Betamethasone 21-O-Ethyl Carbonate (Betamethasone EP Impurity D) is a derivative of Betamethasone (B327000); a glucocorticoid used as an anti-inflammatory agent.4<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005); Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006); Xiong, Y., et al.: J. Pharmaceut. Biomed., 49, 646 (2009)<br></p>Fórmula:C25H33FO7Cor e Forma:NeatPeso molecular:464.52Betamethasone 9,11-Epoxide 17-Propionate
CAS:Produto Controlado<p>Impurity Betamethasone Dipropionate EP Impurity U<br>Applications Betamethasone 9,11-Epoxide 17-Propionate (Betamethasone Dipropionate EP Impurity U) is an impurity of Betamethasone (B327000), an antiinflammatory agent.<br></p>Fórmula:C25H32O6Cor e Forma:NeatPeso molecular:428.525β-Dihydrocortisone Acetate 21-Acetate
CAS:Produto Controlado<p>Applications Cortisone (C696500) derivative.<br></p>Fórmula:C23H32O6Cor e Forma:NeatPeso molecular:404.522b-Hydroxy Cholesterol
CAS:Produto Controlado<p>Applications The 22S-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.<br>References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),<br></p>Fórmula:C27H46O2Cor e Forma:Off White SolidPeso molecular:402.65Betamethasone 21-Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity E<br>Applications Betamethasone 21-Valerate (Betamethasone Valerate EP Impurity E) is an isomeric impurity of Betamethasone 17-Valerate (B327075), as an corticosteroid. Betamethasone 21-Valerate was generated in the stress study of the active drug Betamethasone 17-Valerate (B327075).<br>References Caron, J.C., et al.: J. Pharmaceut. Sci., 73, 1703 (1984); Stouch, T.R., et al.: J. Med. Chem., 29, 2125 (1986);<br></p>Fórmula:C27H37FO6Cor e Forma:WhitePeso molecular:476.58Betamethasone 17-Valerate
CAS:Produto Controlado<p>Applications Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate has been shown to inhibit heat-induced vasodilatation in man.<br>References Banfi, S. et al.: Curr. Ther. Res., 19, 126 (1976); Ahluwalia, A. et al.: Br. J. Dermatol., 128, 45 (1993);<br></p>Fórmula:C27H37FO6Cor e Forma:WhitePeso molecular:476.587-Keto Cholesterol
CAS:Produto Controlado<p>Applications 7-Keto Cholesterol is a metabolite of Cholesterol.<br>References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),<br></p>Fórmula:C27H44O2Pureza:~98%Cor e Forma:NeatPeso molecular:400.64Testosterone 17-Isobutyrate
CAS:Produto Controlado<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Fórmula:C23H34O3Cor e Forma:Off-WhitePeso molecular:358.51Triamcinolone Furetonide
CAS:Produto ControladoFórmula:C33H35FO8Cor e Forma:NeatPeso molecular:578.62Flurandrenolone Acetate
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Fórmula:C26H35FO7Cor e Forma:NeatPeso molecular:478.555β-Dihydrocortisol-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 5β-Dihydrocortisol-d6 is an isotope labelled analog of 5β-Dihydrocortisol (D448595). 5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Fórmula:C21H26D6O5Cor e Forma:NeatPeso molecular:370.51Dydrogesterone-d6 (Major)
CAS:Produto Controlado<p>Applications Labelled Dydrogesterone. A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),<br></p>Fórmula:C21H22D6O2Cor e Forma:NeatPeso molecular:318.48Progesterone 3-(O-carboxymethyl)oxime
CAS:Produto Controlado<p>Applications Progesterone 3-(O-carboxymethyl)oxime is used in microtitre plate enzyme immunoassays (EIAs) for progesterone.<br></p>Fórmula:C23H33NO4Cor e Forma:NeatPeso molecular:387.5126-Ketoprogesterone
CAS:Produto Controlado<p>Applications 6-Ketoprogesterone is used in the synthesis and biological evaluation of steroidal deivatives as selective inhibitors of AKR1B10. AKR1B10 is a promising anti-cancer therapeutic target.<br>References Zhang, W., et al.: Steroids, 86, 39 (2014)<br></p>Fórmula:C21H28O3Cor e Forma:NeatPeso molecular:328.45Fulvestrant-d3
CAS:Produto ControladoFórmula:C32H44D3F5O3SCor e Forma:White To Off-WhitePeso molecular:609.79Latanoprost
CAS:<p>Applications Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye.<br>References Rhee, D.J., et al.: Clinic. Ophthalmol., 2, 313 (2008), Hernandez, M., et al.: Exp. Eye Res., 86, 798 (2008), Nagata, T., et al.: J. Pharmacol. Sci., 106, 423 (2008), Ikeda, Y., et al.: J. Ocular Pharmacol. Ther., 24, 230 (2008),<br></p>Fórmula:C26H40O5Cor e Forma:Light YellowPeso molecular:432.59Norethindrone 3-Isopropyl Enol Ether
Produto ControladoFórmula:C23H32O2Cor e Forma:NeatPeso molecular:340.4996-Dehydroprogesterone
CAS:Produto Controlado<p>Applications 6-Dehydroprogesterone is an impurity found in progesterone (P755900).<br>References Maslov, L., et al.: Khimiko-Farmatsevticheskii Zhurnal, 29, 53 (1995); Sokolova, T., et al.: Khimiko-Farmatsevticheskii Zhurnal , 19, 236 (1985)<br></p>Fórmula:C21H28O2Cor e Forma:NeatPeso molecular:312.45Dienogest-d8 (major)
CAS:Produto Controlado<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Fórmula:C20H17D8NO2Cor e Forma:Light YellowPeso molecular:319.4717β-Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity D<br>Applications 17b-Estradiol is the major estrogen (1) secreted by the premenopausal ovary (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Fórmula:C18H24O2Cor e Forma:NeatPeso molecular:272.38Palovarotene
CAS:Produto Controlado<p>Applications Palovarotene, is a highly selective retinoic acid receptor gamma (RAR-γ) agonist that is under investigation as a potential treatment for emphysema.<br>References Hind, M., et al.: Curr. Opinion Invest. Drugs, 10(11), 1243 (2009); Stolk, J., et al.: Therap. advances Respi. dise., 4, 319 (2010);<br></p>Fórmula:C27H30N2O2Cor e Forma:NeatPeso molecular:414.545(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (>90%)
CAS:Produto Controlado<p>Impurity Levonorgestrel EP Impurity P<br>Applications 5(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (Levonorgestrel EP Impurity P) is a Norgestrel (N689500) impurity.<br></p>Fórmula:C21H28O2Pureza:>90%Cor e Forma:NeatPeso molecular:312.45Paricalcitol
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Fórmula:C27H44O3Cor e Forma:NeatPeso molecular:416.64(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.<br>References Vir Singh, T., et al.: ARKAT USA, INc., (2002);<br></p>Fórmula:C22H28O5Cor e Forma:White To Light RedPeso molecular:372.45Testosterone Laurate
CAS:Produto ControladoFórmula:C31H50O3Cor e Forma:White To Off-WhitePeso molecular:470.73Pregnenolone monosulfate
CAS:<p>Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a potent nootropic steroid used in the study of neuroticism and depression.</p>Fórmula:C21H32O5SPureza:99.46%Cor e Forma:SolidPeso molecular:396.545α-Androstanedione
CAS:Produto Controlado<p>Applications 5α-Androstanedione is a metabolite of Androstendione (A637550). 5α-Androstanedione is an important intermediate in the conversion of Androstenedione to Androstanolone (A637540).<br>References Milewich, L., et al.: J. Steroid Chem., 16, 81 (1982); Stanczyk, F. Z., et al.: J. Steroid Biochem. Mol. Biol., 37, 129 (990);<br></p>Fórmula:C19H28O2Cor e Forma:NeatPeso molecular:288.42O,O-Dimethyl Methylphosphonate
CAS:Produto Controlado<p>Applications O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents.<br>References Jang, S.H., et al.: J. Korean. Phy. Soc., 55, 294 (2009); Schneider, B.B., et al.: Int. J. Mass. Spectro., 298, 45 (2010);<br></p>Fórmula:C3H9O3PCor e Forma:NeatPeso molecular:124.076Fluvastatin
CAS:<p>Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.</p>Fórmula:C24H26FNO4Pureza:98.94%Cor e Forma:SolidPeso molecular:411.47Desonide-21-aldehyde Hydrate
Produto ControladoFórmula:C24H32O7Cor e Forma:White To Light YellowPeso molecular:432.507Deflazacort
CAS:Produto Controlado<p>Applications A systemic corticosteroid. A derivative of prednisolone. Used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Fórmula:C25H31NO6Cor e Forma:NeatPeso molecular:441.52Digitoxin
CAS:<p>Stability Hygroscopic<br>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Fórmula:C41H64O13Cor e Forma:White To Off-WhitePeso molecular:764.944-Hydroxy Testosterone
CAS:Produto Controlado<p>Applications 4-Hydroxytestosterone is an anabolic steroid and does not have any therapeutic indication. 4-Hydroxytestosterone is metabolite of the aromatase inhibitor Formestane (F692250). 4-Hydroxytestosterone concentration in the urine can be used as a biomarker for steroid misuse.Controlled Substance.<br>References Kohler, M. et al.: Steroids, 72, 278 (2007); Brodie, A.M. et al.: J. Steroid. Biochem., 14, 693 (1981); Van Renterghem, P. et al.: Steroids, 75, 154 (2010);<br></p>Fórmula:C19H28O3Cor e Forma:NeatPeso molecular:304.4216α-Homo 2-(Hydroxymethyl)betamethasone
CAS:Produto ControladoFórmula:C22H29FO5Cor e Forma:NeatPeso molecular:392.461Betamethasone Acid
CAS:Produto Controlado<p>Applications Betamethasone Acid is a derivative of Betamethasone (B327000), a gluccocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C21H27FO5Cor e Forma:NeatPeso molecular:378.43Estrone
CAS:Produto Controlado<p>Impurity Estradiol EP Impurity A/ Ethinylestradiol EP Impurity C<br>Applications Estrone is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Fórmula:C18H22O2Cor e Forma:White To Off-WhitePeso molecular:270.37(3α)-Allopregnanolone-d5
CAS:Produto Controlado<p>Applications Labelled (3α)-Allopregnanolone. (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain.<br>References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);<br></p>Fórmula:C21H29D5O2Cor e Forma:NeatPeso molecular:323.52Fluocinolone Acetonide-21-carboxylic Acid (>90%)
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity A<br>Applications Fluocinolone Acetonide-21-carboxylic Acid, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C24H28F2O7Pureza:>90%Cor e Forma:Off WhitePeso molecular:466.476-Keto 17b-Estradiol
CAS:Produto ControladoFórmula:C18H22O3Cor e Forma:Off-WhitePeso molecular:286.37Dexamethasone 21-Palmitate-d31
CAS:Produto Controlado<p>Applications A labelled orticosteroid prodrug for the treatment of eye disorders.<br>References Benameur, H., et al.: J. Pharm. Pharmacol., 47, 812 (1995), Tauchi, Y., et al.: Biol. Pharm. Bull., 24, 925 (2001), Chono, S., et al.: J. Drug Targeting, 13, 407 (2005),<br></p>Fórmula:C38D31H28FO6Cor e Forma:NeatPeso molecular:662.06Estrone-d2
CAS:Produto Controlado<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Fórmula:C182H2H20O2Cor e Forma:Off-WhitePeso molecular:272.3817a-Hydroxy-5a-androstan-3-one
CAS:Produto Controlado<p>Applications 17α-Hydroxy-5α-androstan-3-one is a metabolite of epi-testosterone (T155005). It functions similar to other testosterone analogs, maintaining cell conformation in epithelial cells.<br>References Sinowatz, F. et al.: J. Endocrinol., 73, 53 (1977);<br></p>Fórmula:C19H30O2Cor e Forma:NeatPeso molecular:290.44Obeticholic Acid Acyl-β-D-glucuronide
Produto Controlado<p>Applications Obeticholic Acid Acyl-β-D-glucuronide is composed of 6-Ethylchenodeoxycholic Acid (E899810) linked with Glucuronic Acid (G596850).<br>References Levene, M., et al.: J. Biol. Chem., 92, 257 (1931); Miyamoto, I., et al.: Anal. Biochem., 115, 308 (1981); Neuschwander-Tetri, B.A., et al.: Lancet., 385, 956 (2015);<br></p>Fórmula:C32H52O10Cor e Forma:White To Off-WhitePeso molecular:596.75Δ5(10),6,8(9)-D-(-)-Norgestrel
CAS:Produto ControladoFórmula:C21H24O2Cor e Forma:NeatPeso molecular:308.41417α-Dihydro Equilin
CAS:Produto Controlado<p>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H22O2Cor e Forma:NeatPeso molecular:270.3725-Hydroxy Vitamin D2
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Vitamin D2 (V676040).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barnes, P., et al.: J. Clin. Invest., 83, 1527 (1989), Holick, M., et al.: J. Cell Biochem., 88(2), 296 (2003), Maunsell, Z., et al.: Clin. Chem., 51, 1683 (2005),<br></p>Fórmula:C28H44O2Cor e Forma:White To Light YellowPeso molecular:412.65(3S,3aS,5aS,6R,9aS,9bS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]dodecahydro-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid
CAS:Produto ControladoFórmula:C23H37NO4Cor e Forma:NeatPeso molecular:391.544Cholesterol 3-Acetate-d7
CAS:Produto ControladoFórmula:C29H41D7O2Cor e Forma:NeatPeso molecular:435.73(aR,1S,3S,4R)-a,4-Dimethyl-2-oxo-3-(3-oxobutyl)-cyclohexaneacetic Acid
CAS:Produto Controlado<p>Stability Hygroscopic, Unstable in Solution<br>Applications (αR,1S,3S,4R)-α,4-Dimethyl-2-oxo-3-(3-oxobutyl)-cyclohexaneacetic Acid is an impurity of Artemisin (A777500), an active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Klayman, D.L., et al.: Science, 228, 1049 (1985), Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000), Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),<br></p>Fórmula:C14H22O4Cor e Forma:NeatPeso molecular:254.32Boldione
CAS:Produto Controlado<p>Impurity USP Exemestane Related Compound C<br>Applications Boldenone related steroid; anabolic androgenic steroid.<br>References Watanabe, K., et al.: J. Appl. Bacteriol., 62, 1511 (1987), Barthakur, S., et al.: J. Basic Microbiol., 36, 383 (1996),Grinenko, G., et al.: Pharmaceut. Chem. J., 36, 510 (2002), Bhat, S., et al.: J. Biol. Chem., 280, 33015 (2005),<br></p>Fórmula:C19H24O2Cor e Forma:NeatPeso molecular:284.395-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
CAS:Produto Controlado<p>Applications 5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide is a photodegradation product of Atorvastatin (A791750).<br>References Cermola, F., et al.: Tetrahedron., 62, 7390 (2006);<br></p>Fórmula:C33H33FN2O5Cor e Forma:NeatPeso molecular:556.62Testosterone-3,4-13C2
CAS:Produto ControladoFórmula:C1713C2H28O2Cor e Forma:NeatPeso molecular:290.4121-Desacetyl Deflazacort
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Deflazacort, a systemic corticosteroid, a derivative of prednisolone and used for rheumatoid arthritis and lupus.<br>References Hahn, T.J., et al.: Calcif. Tissue Int., 31, 109 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984)<br></p>Fórmula:C23H29NO5Cor e Forma:White To Off-WhitePeso molecular:399.48Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
CAS:Produto Controlado<p>Impurity Dutateride EP Impurity C<br>Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.<br>References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);<br></p>Fórmula:C21H31NO3Cor e Forma:White To Off-WhitePeso molecular:345.48Desonide-13C3
CAS:Produto Controlado<p>Applications Anti-inflammatory.<br>References Phillips, et al.: Toxicol. Appl. Pharmacol., 20, 522 (1971), Sanen, F.J., et al.: Int. J. Clin. Pharmacol. Biopharm., 12, 174 (1975), Tarayre, J.P., et al.: Pharmacol., 19, 323 (1979).<br></p>Fórmula:C2113C3H32O6Cor e Forma:NeatPeso molecular:419.49Dexamethasone Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity C<br>Stability Hygroscopic<br>Applications Dexamethasone Valerate (Betamethasone Valerate EP Impurity C) is an impurity of Dexamethasone (D298800), which is a glucocorticoid that is used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C27H37FO6Cor e Forma:Off-WhitePeso molecular:476.5811-β,16-α,17-α,21-Tetrahydroxypregna-1,4-diene-3,20-dione
Fórmula:C21H28O6Cor e Forma:NeatPeso molecular:376.44Testosterone Sulfate-d3 Triethylamine Salt
CAS:Produto Controlado<p>Applications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Fórmula:C25H40D3NO5SCor e Forma:Off-WhitePeso molecular:472.7Estradiol Enanthate
CAS:<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Fórmula:C25H36O3Cor e Forma:BeigePeso molecular:384.55Cholesterol
CAS:<p>Applications Cholesterol is a major component of all biological membranes; ~25% of total brain lipid is Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. This compound is a contaminant of emerging concern (CECs).<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C27H46OCor e Forma:WhitePeso molecular:386.6520(S)-Hydroxy Prednisolone
CAS:Produto Controlado<p>Impurity Prednisolone EP Impurity G<br>Applications 20(S)-Hydroxy Prednisolone (Prednisolone EP Impurity G) is a Prednisolone (P703740) metabolite.<br>References Kim, H., et al.: J. Med. Chem., 30, 2239 (1987), Addison, R., et al.: J. Steroid Biochem., Mol. Biol., 39, 83 (1991),<br></p>Fórmula:C21H30O5Cor e Forma:NeatPeso molecular:362.461,2-Dihydro Exemestane
CAS:Produto Controlado<p>Impurity USP Exemestane Related Compound A<br>Applications 1,2-Dihydro Exemestane is a related compound of Exemestane (E957000).<br>References Johannessen, D., et al.: Clin. Cancer Res., 3, 1101 (1997), Kaufmann, M., et al.: J. Clin. Oncol., 18, 1399 (2000), Coombes, R., et al.: Lancet, 369, 559 (2007),<br></p>Fórmula:C20H26O2Cor e Forma:NeatPeso molecular:298.4217β-Estradiol-d3 17-Acetate
CAS:Produto Controlado<p>Applications Protected Estradiol.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Fórmula:C20H23D3O3Cor e Forma:NeatPeso molecular:317.442-Bromo 17β-Estradiol
CAS:<p>Stability Light Sensitive<br>Applications 17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.<br>References Numazawa, M. et al.: J. Steroid. Biochem. Mol. Biol., 96, 51 (2005); Vollmer, G. et al.: J. Seroid. Biochem. Mol. Biol., 39, 359 (1991); Brueggemeier, R. et al.: J. Steroid. Biochem., 21, 709 (1984)<br></p>Fórmula:C18H23BrO2Cor e Forma:NeatPeso molecular:351.284-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt, is a glucuronide derivative of 4-Hydroxy-17β-estradiol (H941895); a metabolite of Estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985); Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991); Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998); Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000); Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986); Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987)<br></p>Fórmula:C24H32O9•xNaCor e Forma:NeatPeso molecular:464.511,2-Dihydrobudesonide (Mixture of diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity G<br>Applications 1,2-Dehydrobudesonide (Budesonide EP Impurity G) is an impurity in the synthesis of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Fórmula:C25H36O6Cor e Forma:NeatPeso molecular:432.55Budesonide-d6
CAS:Produto Controlado<p>Applications Labelled Budesonide, a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Fórmula:C25H28D6O6Cor e Forma:NeatPeso molecular:436.576β-Hydroxycortisone
CAS:<p>Applications 6β-Hydroxycortisone can be used as a probe to detect inhibition of CYP3A4 in vivo.<br>References Peng, C.C., et. al.: Clin. Pharmacol. Ther., 89, 888 (2011)<br></p>Fórmula:C21H28O6Cor e Forma:NeatPeso molecular:376.44Estradiol Benzoate
CAS:<p>Applications Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.<br>References MacLusky, N., et al.: Endocrinology, 106, 192 (1980), Apostolakis, E., et al.: J. Neurosci., 16, 4823 (1996), Guarraci, F., et al.: Brain Res., 999, 40 (2004), Petralia, S., et al.: J. Neuroendocrinol., 18, 902 (2006),<br></p>Fórmula:C25H28O3Cor e Forma:WhitePeso molecular:376.494-Hydroxy Estrone
CAS:Produto ControladoFórmula:C18H22O3Cor e Forma:Light Brown SolidPeso molecular:286.37Estradiol-13C2 17-Benzoate
CAS:<p>Applications Estradiol-13C2 17-Benzoate is an intermediate in the synthesis of 17β-Estradiol-13C2 (E888003). Isotope labelled 17β-Estradiol (E888000) is the major estrogen (1) secreted by the premenopausal ovary (2).<br></p>Fórmula:C2313C2H28O3Pureza:>90%Cor e Forma:NeatPeso molecular:378.47Fluocinolone Acetonide-21-aldehyde
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity D<br>Stability Hygroscopic<br>Applications Fluocinolone acetonide-21-aldehyde, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C24H28F2O6Cor e Forma:White To Light YellowPeso molecular:450.47δ4-Pregnen-20α-ol-3-one
CAS:Produto Controlado<p>Impurity Progesterone EP Impurity B<br>Applications Δ4-Pregnen-20α-ol-3-one (Progesterone EP Impurity B) is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.<br>References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);<br></p>Fórmula:C21H32O2Cor e Forma:Off White SolidPeso molecular:316.48Dexamethasone 9,11-Epoxide-d5
CAS:Produto Controlado<p>Applications Dexamethasone 9,11-Epoxide-d5, is the labeled analogue of the unlabeled (D298795 ), a Dexamethasone intermediate.<br>References Isogai, M., et al.: J. Steroid Biochem. Mol. Biol., 44, 141 (1993),<br></p>Fórmula:C22H23D5O5Cor e Forma:Off-WhitePeso molecular:377.49Testosterone Sulfate Triethylamine Salt
CAS:Produto Controlado<p>Applications A metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Fórmula:C25H43NO5SCor e Forma:NeatPeso molecular:469.68Clobetasone 17-Propionate
CAS:Produto Controlado<p>Impurity Clobetasone Butyrate EP Impurity H<br>Applications Clobetasone-17-propionate is derived from Clobetasol (Clobetasol Propionate EP Impurity G) (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986)<br></p>Fórmula:C25H30ClFO5Cor e Forma:NeatPeso molecular:464.95Prednisolone 21-β-D-Glucuronide
CAS:<p>Applications Prednisolone 21-β-D-Glucuronide Sodium Salt is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Fórmula:C27H35NaO11Cor e Forma:NeatPeso molecular:558.55Betamethasone 6α-Bromo 17-Valerate
Produto Controlado<p>Applications Betamethasone 6α-Bromo 17-Valerate is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C27H36BrFO6Cor e Forma:NeatPeso molecular:555.479,11-Anhydrobudesonide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity H<br>Applications 9,11-Anhydrobudesonide (Budesonide EP Impurity H) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Fórmula:C25H32O5Cor e Forma:NeatPeso molecular:412.524-Hydroxy Estrone 1-N7-Guanine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H25N5O4Cor e Forma:NeatPeso molecular:435.486β-Hydroxy Betamethasone
CAS:Produto Controlado<p>Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.<br>References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)<br></p>Fórmula:C22H29FO6Cor e Forma:NeatPeso molecular:408.46Cholesterol-d7
CAS:Produto Controlado<p>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C272H7H39OCor e Forma:NeatPeso molecular:393.70Testosterone β-D-Glucuronide Monosodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug Metab. Disposition, 37, 417 (2009),<br></p>Fórmula:C25H35O8·NaCor e Forma:White To Off-WhitePeso molecular:486.53
![(3S,3aS,5aS,6R,9aS,9bS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]dodecahydro-3a,6-dimethyl-7-oxo-1H-b…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD324050.webp&w=3840&q=75)
