Nucleosídeos e Nucleotídeos
Os nucleosídeos são compostos formados por uma base nitrogenada ligada a um açúcar (ribose ou desoxirribose). Quando um grupo fosfato é adicionado ao nucleosídeo, forma-se um nucleotídeo. Esses compostos são essenciais na biologia celular, pois os nucleotídeos são os blocos fundamentais do DNA e RNA, responsáveis pelo armazenamento e transmissão da informação genética. Os nucleosídeos têm aplicações no tratamento de doenças virais, atuando como inibidores da replicação viral. Os nucleotídeos, além do seu papel estrutural nos ácidos nucleicos, participam de processos energéticos, como a síntese de ATP.
Na CymitQuimica, oferecemos uma ampla gama de nucleosídeos e nucleotídeos essenciais para pesquisa em biologia molecular, virologia e farmacologia.
Foram encontrados 3413 produtos de "Nucleosídeos e Nucleotídeos"
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Cladribine
CAS:<p>Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.</p>Fórmula:C10H12ClN5O3Pureza:99.58% - >99.99%Cor e Forma:White Crystalline SolidPeso molecular:285.69CNQX disodium
CAS:<p>CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.</p>Fórmula:C9H2N4Na2O4Pureza:97.77%Cor e Forma:SolidPeso molecular:276.12Desciclovir
CAS:<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Fórmula:C8H11N5O2Pureza:99.54%Cor e Forma:SolidPeso molecular:209.21Enprofylline
CAS:<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Fórmula:C8H10N4O2Pureza:98.37%Cor e Forma:SolidPeso molecular:194.19Nelarabine
CAS:<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Fórmula:C11H15N5O5Pureza:98.10% - 99.6%Cor e Forma:White SolidPeso molecular:297.27Deoxycytidine triphosphate trisodium salt
CAS:<p>Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.</p>Fórmula:C9H13N3Na3O13P3Pureza:99.80%Cor e Forma:SolidPeso molecular:533.1Azvudine
CAS:<p>Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.</p>Fórmula:C9H11FN6O4Pureza:99.76% - >99.99%Cor e Forma:SolidPeso molecular:286.22Diquafosol tetrasodium
CAS:<p>Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film</p>Fórmula:C18H22N4Na4O23P4Pureza:98.25% - 99.97%Cor e Forma:SolidPeso molecular:878.23Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Fórmula:C9H16N3O13P3Pureza:99.68%Cor e Forma:SolidPeso molecular:467.16Creatine
CAS:<p>Creatine, an amino acid in vertebrates, forms phosphocreatine in muscle, aids energy transfer, is made in the liver, and mainly stored in muscles.</p>Fórmula:C4H9N3O2Pureza:99.63% - 99.83%Cor e Forma:Colourless To Light Yellow SolidPeso molecular:131.13Adenosine 5'-diphosphate
CAS:<p>Adenosine 5'-diphosphate (ADP) is a natural nucleotide derived from the dephosphorylation of ATP. ADP induces platelet aggregation. Cost effective and quality assured.</p>Fórmula:C10H15N5O10P2Pureza:99.5% - >99.99%Cor e Forma:SolidPeso molecular:427.2Lamivudine
CAS:<p>Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.</p>Fórmula:C8H11N3O3SPureza:99.56% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:229.26Melamine
CAS:<p>Melamine is used for making resin, and forms in mammals after eating cyromazine.</p>Fórmula:C3H6N6Pureza:99.49%Cor e Forma:White Solid PowderPeso molecular:126.12Uridine triphosphate trisodium salt
CAS:<p>Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.</p>Fórmula:C9H12N2Na3O15P3Pureza:99.82% - 99.83%Cor e Forma:White PowderPeso molecular:550.09ATP
CAS:<p>ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis.</p>Fórmula:C10H16N5O13P3Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:507.18Adefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Fórmula:C8H12N5O4PPureza:99.56%Cor e Forma:White To Off-White PowderPeso molecular:273.19Cabotegravir
CAS:<p>Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (</p>Fórmula:C19H17F2N3O5Pureza:98.55% - 99.92%Cor e Forma:SolidPeso molecular:405.352-Aminopurine
CAS:<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Fórmula:C5H5N5Pureza:99.51%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:135.13Caroverine hydrochloride
CAS:<p>Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.</p>Fórmula:C22H28ClN3O2Pureza:98.37% - 98.75%Cor e Forma:SolidPeso molecular:401.9Cidofovir
CAS:<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Fórmula:C8H14N3O6PPureza:99.24% - 99.76%Cor e Forma:Fluffy White PowderPeso molecular:279.19CX516
CAS:<p>CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.</p>Fórmula:C14H15N3OPureza:99.04% - ≥95%Cor e Forma:Tan SolidPeso molecular:241.29S29434
CAS:<p>S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).</p>Fórmula:C21H18N4O3Pureza:99.92%Cor e Forma:SolidPeso molecular:374.39Inosine
CAS:<p>Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Low-Cost!</p>Fórmula:C10H12N4O5Pureza:99.51% - 99.89%Cor e Forma:SolidPeso molecular:268.23Peramivir Trihydrate
CAS:<p>Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are</p>Fórmula:C15H28N4O4·3H2OPureza:99.52% - ≥95%Cor e Forma:SolidPeso molecular:382.45Dapagliflozin
CAS:<p>Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.</p>Fórmula:C21H25ClO6Pureza:99.5% - 99.93%Cor e Forma:SolidPeso molecular:408.87cangrelor tetrasodium
CAS:<p>Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.</p>Fórmula:C17H21Cl2F3N5Na4O12P3S2Pureza:98.51% - 98.6%Cor e Forma:SolidPeso molecular:864.29Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H15BrN6OPureza:97.61% - 99.74%Cor e Forma:White To Off-White SolidPeso molecular:435.28IDRA-21
CAS:<p>IDRA-21 is a positive AMPA receptor modulator.</p>Fórmula:C8H9ClN2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:232.69Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Fórmula:C20H23CaN7O6Pureza:97.35%Cor e Forma:Off-White To Pale Yellow SolidPeso molecular:497.52Dexelvucitabine
CAS:<p>Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C9H10FN3O3Pureza:98.25%Cor e Forma:SolidPeso molecular:227.19Cidofovir dihydrate
CAS:<p>Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.</p>Fórmula:C8H18N3O8PPureza:99.44%Cor e Forma:SolidPeso molecular:315.22Fludarabine Phosphate
CAS:<p>Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.</p>Fórmula:C10H13FN5O7PPureza:99.25% - 99.78%Cor e Forma:SolidPeso molecular:365.21Hibifolin
CAS:<p>Hibifolin is a flavonol glycoside natural product,is a potential inhibitor of adenosine deaminase (Ki of 49.92 μM).</p>Fórmula:C21H18O14Pureza:98.92%Cor e Forma:SolidPeso molecular:494.361,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Fórmula:C9H7NO2Pureza:98.29% - 99.35%Cor e Forma:Of White To White PowderPeso molecular:161.16Dilazep dihydrochloride
CAS:<p>Dilazep dihydrochloride inhibits adenosine uptake, ischemia, nucleoside transport, platelet aggregation, and acts as a vasodilator.</p>Fórmula:C31H46Cl2N2O10Pureza:98.39%Cor e Forma:SolidPeso molecular:677.61Remdesivir
CAS:<p>Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of</p>Fórmula:C27H35N6O8PPureza:97.62% - 99.98%Cor e Forma:SolidPeso molecular:602.58Uridine
CAS:<p>Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.</p>Fórmula:C9H12N2O6Pureza:99.08% - 99.82%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:244.2Adenosine monophosphate
CAS:<p>AMP is a purine nucleotide, vital in cell signaling and energy regulation, and inhibits EC 3.1.3.11 and 3.1.3.1, also an A1 receptor agonist.</p>Fórmula:C10H14N5O7PPureza:99.59% - 99.84%Cor e Forma:Crystals From Water + Acetone SolidPeso molecular:347.22GKT136901
CAS:<p>GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite</p>Fórmula:C19H15ClN4O2Pureza:99.16%Cor e Forma:SolidPeso molecular:366.8NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Fórmula:C21H26N7Na4O17P3Pureza:97.15% - >99.99%Cor e Forma:SolidPeso molecular:833.35NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Cor e Forma:SolidPeso molecular:1142.12Thiamine pyrophosphate chloride
CAS:<p>Thiamine pyrophosphate, a vitamin B1 derivative, is a coenzyme in transketolase studies for decarboxylation in biology.</p>Fórmula:C12H19ClN4O7P2SPureza:98.29% - 99.72%Cor e Forma:SolidPeso molecular:460.76ASP-9521
CAS:<p>ASP-9521 is a selective, potent and orally active indole-based AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3.Cost-effective and quality-assured.</p>Fórmula:C19H26N2O3Pureza:95.11% - 96.96%Cor e Forma:SolidPeso molecular:330.42Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:381.42Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Fórmula:C9H13N5NaO4Pureza:99.93%Cor e Forma:SolidPeso molecular:278.22Didanosine
CAS:<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Fórmula:C10H12N4O3Pureza:99.64%Cor e Forma:White Crystalline PowderPeso molecular:236.23Cytosine
CAS:<p>Cytosine is a pyrimidine nucleic acid base; its deamination can cause mutations in leukemia and cancer.</p>Fórmula:C4H5N3OPureza:99.67%Cor e Forma:SolidPeso molecular:111.1Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Fórmula:C22H29FN3O9PPureza:99.77% - 99.82%Cor e Forma:SolidPeso molecular:529.45Cytidine 5'-monophosphate
CAS:<p>Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA.</p>Fórmula:C9H14N3O8PPureza:98.78% - 99.10%Cor e Forma:SolidPeso molecular:323.20N2-Nitroso Folinic Acid (N2-Nitroso Folic Acid USP Related Compound A (Free Form), N2-Nitroso Leucovorin)
Fórmula:C20H22N8O8Peso molecular:502.44Flavine Adenine Dinucleotide Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase.<br>References DeLuca, K., et al.: J. Biol. Chem., 223, 569 (1956), Yagi, K., et al.: Biochemistry, 19, 1553 (1980), Li, G., et al.: J. Phys. Chem., 112, 4573 (2008),<br></p>Fórmula:C27H31N9O15P2·2NaCor e Forma:NeatPeso molecular:829.51Viaminate
CAS:Produto Controlado<p>Applications Viaminate is a pharmaceutical used to treat severe acne and other keratinization disorders. Viaminate can be taken orally, or topically in prepared gels and creams.<br>References Zhang, H.; et al.: Am. J. Med. Sci., 356, 84 (2018); Lu, J.; et al.: Zhongguo Yaofang, 22, 155 (2011); Li, G.: Zhonghua Yiyao Zazhi, 7, 536 (2007).<br></p>Fórmula:C29H37NO3Cor e Forma:Light YellowPeso molecular:447.61Entecavir
CAS:<p>Applications An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Fórmula:C12H15N5O3Cor e Forma:NeatPeso molecular:277.28Canagliflozin 2-Glucuronide
CAS:Produto Controlado<p>Applications Canagliflozin 2-glucuronide is a derivative of Canagliflozin (C175190). Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion.<br>References Devineni, D., et al.: Diab. Obes. Metab., 14, 539 (2012); Nicolle, L., et al.: Curr. Med. Res. Opin., 28, 1167 (2012)<br></p>Fórmula:C30H33FO11SCor e Forma:NeatPeso molecular:620.64Penciclovir
CAS:<p>Applications An antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Fórmula:C10H15N5O3Cor e Forma:NeatPeso molecular:253.265-Methyluridine
CAS:<p>Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.<br>References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),<br></p>Fórmula:C10H14N2O6Cor e Forma:NeatPeso molecular:258.23Adenosine 5'-Monophosphate
CAS:Produto Controlado<p>Applications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.<br>References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)<br></p>Fórmula:C10H14N5O7PCor e Forma:NeatPeso molecular:347.225-Methyl-2’-deoxy Cytidine
CAS:<p>Applications A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).<br>References Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008),<br></p>Fórmula:C10H15N3O4Cor e Forma:NeatPeso molecular:241.243’-Amino-3’-deoxythymidine
CAS:Produto Controlado<p>Impurity Zidovudine Impurity;<br>Stability Hygroscopic, Moisture Sensitive<br>Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT).<br>References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),<br></p>Fórmula:C10H15N3O4Cor e Forma:White To Off-WhitePeso molecular:241.24Entecavir-13C2,15N
CAS:Produto Controlado<p>Applications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Fórmula:C1013C2H15N415NO3Cor e Forma:White To Off-WhitePeso molecular:280.264’-Epi Lamivudine
CAS:Produto Controlado<p>Applications Lamivudine epimer.<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H11N3O3SCor e Forma:NeatPeso molecular:229.26RO 2433
CAS:Produto Controlado<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Fórmula:C10H13FN2O5Cor e Forma:NeatPeso molecular:260.223’,5’-Di-O-benzyl Entecavir
CAS:Produto Controlado<p>Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).<br>References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Fórmula:C26H27N5O3Cor e Forma:NeatPeso molecular:457.52cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:Produto Controlado<p>Applications Antiviral nucleoside analog, also an impurity found in emtricitabine (E525000).<br>References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Fórmula:C8H9FN2O4SCor e Forma:Off-WhitePeso molecular:248.23Folic Acid-13C5
CAS:<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Fórmula:C5C14H19N7O6Cor e Forma:Dark Yellow To Dark BrownPeso molecular:446.362-Oxa-1,4-butanediol diacetate
CAS:Produto ControladoFórmula:C7H12O5Cor e Forma:NeatPeso molecular:176.17trans-Abacavir Dihydrochloride
CAS:Produto Controlado<p>Applications trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C14H18N6O·2HClCor e Forma:NeatPeso molecular:359.25Adenosine 5’-Monophosphoramidate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Used in the characterization and elucidation of coordination requirements of adenine nucleotides complexes with Fe(II) ions.<br>References Richter, Y., et al.: Nucleos. Nucleot. Nucleic Acids, 22, 1757 (2003),<br></p>Fórmula:C10H14N6O6P·NaCor e Forma:NeatPeso molecular:368.22O-Benzoyllamivudine
CAS:Produto ControladoFórmula:C15H15N3O4SCor e Forma:Off-WhitePeso molecular:333.362N2-Acetyl Acyclovir
CAS:Produto Controlado<p>Impurity Aciclovir EP Impurity F<br>Applications N2-Acetyl Acyclovir (Aciclovir EP Impurity F) is an impurity of Acyclovir (A192400).<br>References Balon, K., et al.: Pharm. Res., 16, 882 (1999),<br></p>Fórmula:C10H13N5O4Cor e Forma:BeigePeso molecular:267.245-Fluoro ent-Lamivudine Acid D-Menthol Ester
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of ent-Emtricitabine (E525005).<br></p>Fórmula:C18H26FN3O4SCor e Forma:NeatPeso molecular:399.486-Deoxypenciclovir
CAS:Produto Controlado<p>Applications A metabolite of Famciclovir, an antiviral.<br>References Harnden, M.R., et al.: J. Med. Chem., 32, 1738 (1989)<br></p>Fórmula:C10H15N5O2Cor e Forma:Off White SolidPeso molecular:237.261R-Dapagliflozin
CAS:Produto Controlado<p>Applications 1R-Dapagliflozin is an isomer of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO6Cor e Forma:NeatPeso molecular:408.883'-Deoxyinosine
CAS:Produto Controlado<p>Impurity Didanosine EP Impurity D<br>Applications 3'-Deoxyinosine (Didanosine EP Impurity D) is an Inosine (I661000) analog with potential use as an antileishmanial drug. Used as an inhibiting agent in studies of Trypanosoma cruzi growth inside host cells in vitro. An impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950).<br>References Morishige, K. et al.: Exp. Parasitol., 80, 665 (1995); Aoki, T. et al.: Adv. Exp. Med. Biol., 370, 499 (1994);<br></p>Fórmula:C10H12N4O4Cor e Forma:NeatPeso molecular:252.23α-Decitabine
CAS:Produto Controlado<p>Applications α-Decitabine is shown to inhibit DNA methylation resulting in an effective anticancer agent.<br>References Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);<br></p>Fórmula:C8H12N4O4Cor e Forma:NeatPeso molecular:228.212,4-Diamino-6-hydroxypyrimidine
CAS:Produto Controlado<p>Applications 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.<br></p>Fórmula:C4H6N4OCor e Forma:NeatPeso molecular:126.12Abacavir-d4
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Abacavir-d4 is deuterium labeled Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Fórmula:C14H14D4N6OCor e Forma:Off-WhitePeso molecular:290.361’-epi-Cladribine
CAS:<p>Applications 1’-epi-Cladribine is an impurity of Cladribine (C557500), a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990),<br></p>Fórmula:C10H12ClN5O3Cor e Forma:NeatPeso molecular:285.69Folinic acid
CAS:<p>Folinic acid (Leucovorin) is a biofolic acid that can be used in the treatment of methotrexate, often in combination with Methotrexate (MTX) to reduce MTX-</p>Fórmula:C20H23N7O7Pureza:99.76%Cor e Forma:Crystals From Water With 3 Mol Of Water Of Crystallization SolidPeso molecular:473.44Floxuridine-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Floxuridine. Antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Fórmula:C813CH11F15N2O5Cor e Forma:WhitePeso molecular:249.17Melamine-15N3
CAS:<p>Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.<br></p>Fórmula:C3H615N3N3Cor e Forma:White To Off-WhitePeso molecular:129.10Dapagliflozin hydroxy Impurity (Mixture of Diastereomers)
CAS:<p>Applications (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol is an impurity of the drug Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO7Cor e Forma:White To Off-WhitePeso molecular:424.872Laninamivir
CAS:<p>Applications A new potent neuraminidase (NA) inhibitor, shows long-acting anti-influenza virus activity.<br>References Bantia, S., et al.: Antimicrob. Agents Chemother., 42, 801 (1998), Honda, T., et al.: Bioorg. Med. Chem. Lett., 12, 1925 (2002), Kiso, M., et al.: Lancet, 364, 759 (2004), Macdonald, S., et al.: J. Med. Chem., 48, 2964 (2005),<br></p>Fórmula:C13H22N4O7Cor e Forma:White To Off-WhitePeso molecular:346.34Zanamivir
CAS:Produto Controlado<p>Applications Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral.<br>References Woods, J.M., et al.: Antimicrob. Agents Chemother., 37, 1473 (1993), Pegg, M.S., et al.: Biochem. Mol. Biol. Int., 32, 851 (1994), Monto, A.S., et al.: J. Am. Med. Assoc., 282, 31 (1999),<br></p>Fórmula:C12H20N4O7Cor e Forma:NeatPeso molecular:332.31Barbituric Acid
CAS:<p>Impurity Fluorouracil EP Impurity A<br>Applications Barbituric Acid (Fluorouracil EP Impurity A) is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties.<br>References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),<br></p>Fórmula:C4H4N2O3Cor e Forma:NeatPeso molecular:128.09Adenosine-3’,5’-cyclic Monophosphate
CAS:<p>Stability Hygroscopic<br>Applications Adenosine-3’,5’-cyclic Monophosphate is an Adenosine (A280400) derivative useful as anticancer agent.<br>References Keast, R., et al.: Pharma. Res., 19, 1019 (2002),<br></p>Fórmula:C10H12N5O6PCor e Forma:NeatPeso molecular:329.21[1',2',3',4',5'-13C5]Uridine
CAS:Produto Controlado<p>Applications Labelled Uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)<br>References Lorine, P., et al.: J. Biol. Chem., 178, 439 (1949); Grakoui, A., et al.: J. Virol., 63, 5216 (1989); Strauss, J., et al.: Microbiol. Rev., 58, 491 (1994); Lin, Y., et al.: Virology, 292, 78 (2002);<br></p>Fórmula:C5C4H12N2O6Cor e Forma:NeatPeso molecular:249.16Etravirine
CAS:Produto Controlado<p>Applications Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection.<br>References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008), Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008),<br></p>Fórmula:C20H15BrN6OCor e Forma:White To Off-WhitePeso molecular:435.281,3-Dioxolane (Stabilized with BHT)
CAS:Produto ControladoFórmula:C3H6O2Cor e Forma:NeatPeso molecular:74.08Baquiloprim
CAS:<p>Stability Hygroscopic<br>Applications Baquiloprim is an amiopyrimidine antibacterial synergist with high activity and slow elimination. Baquiloprim has a better half-life than trimethoprim.<br>References Zhi-hui, H., et al.: Anhui Nongye Kexue, 41, 2503 (2013)<br></p>Fórmula:C17H20N6Cor e Forma:Light YellowPeso molecular:308.382’-Deoxycytidine 5'-Monophosphate Hydrate
CAS:Produto Controlado<p>Applications A phosphorylated metabolite of the deoxyribonucleoside 2’-Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferation.<br>References Holen, E. et al.: Nutrition, 21, 1003 (2005); Alexandre, J.A. et al.: Nucleosides Nucleotides Nucelic Acids, 26, 1375 (2007);<br></p>Fórmula:C9H14N3O7P·xH2OCor e Forma:White To Off-WhitePeso molecular:307.20 + x(18.02)5-Aza Cytosine
CAS:Produto Controlado<p>Impurity Azacitidine USP Related Compound A<br>Applications Inhibits the growth of Escherichia coli. Azacitidine USP Related Compound A.<br>References Shapir, N., et al.: J. Bacteriol., 184, 5376 (2002), Hrdlicka, P., et al.: Bioorg. Med. Chem., 13, 1249 (2005), Krecmerova, M., et al.: J. Med. Chem., 50, 1069 (2007),<br></p>Fórmula:C3H4N4OCor e Forma:White SolidPeso molecular:112.09Gemcitabine-13C,15N2 Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Labelled Gemcitabine, an antineoplastic.<br>References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),<br></p>Fórmula:C813CH12ClF2N15N2O4Cor e Forma:Off-WhitePeso molecular:302.64D-Glucono-1,5-lactone
CAS:Produto Controlado<p>Applications A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.<br>References Jacob, M. et al.: Food Hydrocoll., 25, 928 (2011); Li, J. et al.: J. Sci. Food Agric., 91, 38, 2011;<br></p>Fórmula:C6H10O6Cor e Forma:NeatPeso molecular:178.142’,2’-Difluoro-2’-deoxyuridine
CAS:Produto ControladoFórmula:C9H10F2N2O5Cor e Forma:White To Off-WhitePeso molecular:264.184-[(2-Chloroethyl)amino]-L-phenylalanine Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-[(2-Chloroethyl)amino]-L-phenylalanine is a metabolite of Melphalan (M216900); an antineoplastic.<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)<br></p>Fórmula:C11H15ClN2O2HClCor e Forma:NeatPeso molecular:242.702Dapagliflozin Tetraacetate
CAS:<p>Applications Dapagliflozin Tetraacetate is a derivative of Dapagliflozin [D226255], a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Fórmula:C29H33ClO10Cor e Forma:WhitePeso molecular:577.02ent-Entecavir
CAS:Produto Controlado<p>Applications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900).<br>References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Fórmula:C12H15N5O3Cor e Forma:NeatPeso molecular:277.285-Fluoro Cytosine
CAS:Produto Controlado<p>Applications 5-FC is a toxic antifungal/antimicrobial agent.<br>References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),<br></p>Fórmula:C4H4FN3OCor e Forma:White To Off-WhitePeso molecular:129.09Ribavirin-13C2
CAS:Produto Controlado<p>Applications Ribavirin-13C2 is the labeled analogue of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986); Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993); Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994); Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Fórmula:C613C2H12N4O5Cor e Forma:WhitePeso molecular:246.19α-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS:Produto ControladoFórmula:C22H18Cl2N4O6Cor e Forma:White To Off-WhitePeso molecular:505.308Adenosine-13C5
CAS:<p>Stability Hygroscopic<br>Applications Labelled nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010), Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010),<br></p>Fórmula:C513C5H13N5O4Cor e Forma:White To Off-WhitePeso molecular:272.20N-Des-1-β-D-ribofuranosyl Ribavirin
CAS:<p>Impurity Ribavirin EP Impurity D<br>Applications N-Des-1-β-D-ribofuranosyl Ribavirin (Ribavirin EP Impurity D) is an impurity in the synthesis of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Fórmula:C3H4N4OCor e Forma:Off White SolidPeso molecular:112.09Decarboxylated S-Adenosylmethionine Sulfate Salt
CAS:<p>Stability Hygroscopic<br>Applications Decarboxylated S-Adenosylmethionine Sulfate Salt, is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.<br>References Takahashi,T., et al.: Ann. Bot., 105, 1 (2009); Wu, H., et al.: Biochem., 46, 8331 (2007); Pegg, A., et al.: Biochem., 28, 8446 (1989);<br></p>Fórmula:C14H23N6O3S•H2SO4•HSO4Cor e Forma:White SolidPeso molecular:355.4498079706Ammeline
CAS:<p>Applications Ammeline is a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Fórmula:C3H5N5OCor e Forma:ColourlessPeso molecular:127.10Dapagliflozin 3-O-β-D-Glucuronide
CAS:Produto ControladoFórmula:C27H33ClO12Cor e Forma:NeatPeso molecular:584.9975’-Deoxy-5-fluorocytidine-13C,15N2
CAS:Produto Controlado<p>Applications A labelled metabolite of Capecitabine.<br></p>Fórmula:C813CH12FN15N2O4Cor e Forma:NeatPeso molecular:248.191-β-D-Arabinofuranosyluracil
CAS:<p>Impurity Cytarabine EP Impurity A<br>Applications Antiviral agent. Used for the treatment of severe acute respiratory syndrome (SARS).<br>References Weber, G., et al.: Cancer Res., 43, 3466 (1983), Broet, P., et al.: J. Clin. Oncol., 19, 2778 (2001), Galmarini, C., et al.: Leukemia, 15, 875 (2001), Barth, R., et al.: Cancer Res., 64, 6287 (2004), Song, M., et al.: Bioorg. Med. Chem., 12, 489 (2004),<br></p>Fórmula:C9H12N2O6Cor e Forma:WhitePeso molecular:244.20N-Methyltetrahydrofolic Acid
CAS:Produto Controlado<p>Applications N-Methyltetrahydrofolic acid (cas# 134-35-0) is a useful research chemical.<br></p>Fórmula:C20H25N7O6Cor e Forma:NeatPeso molecular:459.46O-[(Guanin-9-yl)methyl] Acyclovir
CAS:<p>Impurity Aciclovir EP Impurity J<br>Applications O-(Guanin-9-yl)methyl Acyclovir (Aciclovir EP Impurity J) is a dimer impurity of the antiviral agent Acyclovir (A192400).<br>References Ashton, D.S. et al.: J. Chrom. A, 707, 367 (1995);<br></p>Fórmula:C14H16N10O4Cor e Forma:BeigePeso molecular:388.343'-Azido-3'-deoxythymidine
CAS:Produto Controlado<p>Applications A potent and selective inhibitor of HIV-1 replication.<br>References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),<br></p>Fórmula:C10H13N5O4Cor e Forma:White To YellowPeso molecular:267.24Biopterin-d3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Biopterin. A pteridine widely distributed in nature; naturally occurring as the L-erythro-form. Considered as a growth factor for some insects. Fluoresces with a blue color in alkaline solution.<br>References Klatt, P., et al.: J. Biol. Chem., 269, 13861 (1994), Mitnaul, L., et al.: Biochemistry, 92, 885 (1995), Thony, B., et al.: Biochem. J., 347, 1 (2000),<br></p>Fórmula:C92H3H8N5O3Cor e Forma:Beige To BrownPeso molecular:240.234-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
CAS:<p>Applications 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C13H16FN3O6Cor e Forma:Off White PowderPeso molecular:329.28(-)-Inosine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Has neuroprotective properties improving axonal wiring. Has been used to treat stroke patients to restore neural function. Neuroprotective product.<br>References Vandemeulebroucke, A., et al.: Biochem., 49, 8999 (2010), Nestor, G., et al.: J. Agric. Food Chem., 58, 10799 (2010),<br></p>Fórmula:C10H12N4O5Cor e Forma:White To Off-WhitePeso molecular:268.235-Chloro-1-methyl-4-nitroimidazole
CAS:Produto Controlado<p>Impurity Azathioprine EP Impurity C<br>Applications 5-Chloro-1-methyl-4-nitroimidazole (cas# 4897-25-0) is a compound useful in organic synthesis.<br></p>Fórmula:C4H4ClN3O2Cor e Forma:White To Off-WhitePeso molecular:161.551-(Diaminomethylene)-3-b-D-ribofuranosyl-urea Picrate
CAS:Produto Controlado<p>Impurity Azacitidine USP Related Compound C<br>Stability Hygroscopic<br>Applications 1-(Diaminomethylene)-3-β-D-ribofuranosyl-urea Picrate is a related compound of Azacitidine, a DNA metnyltransferase (DNMT) inhibitor for treating myelodysplastic syndromes (MDS).<br>References Rajendiran, C., et al.: PCT Int. Appl. WO 2012135405 A1 20121004 (2012); Ziemba, A., et al.: Chemother Res Pract 965826, 9 (2011); Beisler, J. A., et al.: J. Carbohyd. Chem 4, 281 (1977)<br></p>Fórmula:C7H14N4O5·C6H3N3O7Cor e Forma:YellowPeso molecular:463.31N-Formyl Valacyclovir
CAS:Produto Controlado<p>Impurity Valaciclovir EP Impurity M<br>Applications N-Formyl Valacyclovir (Valaciclovir EP Impurity M) Valacyclovir (V085000) impurity.<br>References Furman, P., et al.: Antimicrob. Agents Chemother., 20, 518 (1981),<br></p>Fórmula:C14H20N6O5Cor e Forma:White To Off-WhitePeso molecular:352.355’-Deoxy-5-fluorouridine
CAS:Produto Controlado<p>Impurity USP Capecitabine Related Compound B<br>Applications 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.<br>References Ingle, J., et al.: Cancer, 67, 886 (1991); Harvey, J., et al.: J. Clin. Oncol., 17, 1474 (1999); Asai-Sato, M., et al.: Int. J. Cancer, 115, 539 (2005); Rastelli, F., et al.: Tumori, 94, 370 (2008);<br></p>Fórmula:C9H11FN2O5Cor e Forma:NeatPeso molecular:246.19Acetyl Vitamin B12
CAS:<p>Applications Acetyl Vitamin B12 is a derivative of Vitamin B12 (V676020). Vitamin B12 gets converted by the body into its bioactive forms, methylcobalamin and cobamamide, which serve as enzyme cofactors. Severe deficiency may result in megaloblastic anemia and/or neurological impairment.<br>References Rickes, et al.: Science, 107, 396 (1948); Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 10, 183 (1981); Grasbeck, R., et al.: Clin. Biochem., 17, 99 (1984)<br></p>Fórmula:C65H90CoN14O15PPureza:>85%Cor e Forma:NeatPeso molecular:1397.405-Fluorouracil-13C,15N2
CAS:<p>Applications Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 221 (1973), Miyashita, O., et al.: Chem. Pharm. Bull., 29, 3181 (1981), Hansen, R.M., et al.: Cancer Invest., 9, 637 (1991),<br></p>Fórmula:C313CH3F15N2O2Cor e Forma:NeatPeso molecular:133.06Capecitabine-2',3'-cyclic Carbonate
CAS:Produto Controlado<p>Impurity Capecitabine EP Impurity F/ USP Capecitabine Related Compound C<br>Applications Capecitabine-2',3'-cyclic Carbonate (Capecitabine EP Impurity F) is a capecitabine related compound C is an impurity in Capecitabine (C175650), an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C16H20FN3O7Cor e Forma:NeatPeso molecular:385.34Emtricitabine Tenofovir Monosoproxil
Produto Controlado<p>Stability Hygrscopic<br>Applications Emtricitabine Tenofovir Monosoproxil is a derivative of Emtricitabine (E525000). Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Fórmula:C23H32FN8O10PSCor e Forma:NeatPeso molecular:662.58Zalcitabine
CAS:Produto Controlado<p>Applications A pyrimidine nucleoside analogue with antiviral activity.<br>References van der Vliet, P.C. and Kwant, M.M.: Biochemistry, 20, 2628 (1981), Mitsuya, H., Broder, S.: Proc. Nat. Acad. Sci. USA, 83, 1911 (1986), Starnes, M.C., and Cheng, Y.: J. Biol. Chem., 262, 988 (1987),<br></p>Fórmula:C9H13N3O3Cor e Forma:NeatPeso molecular:211.22D-2’-Deoxyribofuranosyl-3-guanylurea(α/β-Mixture)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Hydrolytic impurity of D226730 and A796950 (decitabine)<br>References Beisler, Jj.A., et al.: J. Med. Chem., 21, 204 (1978),<br></p>Fórmula:C7H14N4O4Cor e Forma:NeatPeso molecular:218.2105Lamivudine-13C1,d2
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Lamivudine-13C1,d2, is the labeled analogue of Lamivudine (L172502). A reverse transcriptase inhibitor. Antiviral.<br>References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),<br></p>Fórmula:C713CH9D2N3O3SCor e Forma:White PowderPeso molecular:232.26Canagliflozin
CAS:Produto Controlado<p>Applications Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.<br>References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);<br></p>Fórmula:C24H25FO5SCor e Forma:ColourlessPeso molecular:444.52Lamivudine
CAS:Produto Controlado<p>Applications Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.<br>References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),<br></p>Fórmula:C8H11N3O3SCor e Forma:WhitePeso molecular:229.26Cobamamide
CAS:Produto Controlado<p>Applications Cobamamide is an enzyme cofactor that can also regulate gene expression through RNA-base riboswitches.<br>References Ortiz-Guerrero, J.M., et. al.: P. Natl. Acad. Sci. USA, 108, 7565 (2011)<br></p>Fórmula:C72H100CoN18O17PCor e Forma:NeatPeso molecular:1579.585-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt (>90%)
CAS:Produto Controlado<p>Impurity Azathioprine BP Impurity E<br>Stability Light Sensitive<br>Applications 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt is a degradation product of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).<br>References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)<br></p>Fórmula:C4H4N3NaO3Pureza:>90%Cor e Forma:Light Yellow To YellowPeso molecular:165.082-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate
CAS:Produto Controlado<p>Applications Gemcitabine intermediate.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),<br></p>Fórmula:C19H16F2O6Cor e Forma:Colourless To BrownPeso molecular:378.32Emtricitabine
CAS:<p>Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Fórmula:C8H10FN3O3SCor e Forma:Light YellowPeso molecular:247.255-Chlorouracil
CAS:Produto Controlado<p>Impurity Fluorouracil EP Impurity E<br>Applications Used for the experimental and clinical treatment of neoplastic and viral diseases. Fluorouracil EP Impurity E.<br>References Yu, H., et al.: J. Biol. Chem., 268, 15935 (1993), Staleva, L., et al.: Mutat. Res., 370, 81(1996), Harris, V., et al.: J. Mol. Biol., 326, 1389 (2003)<br></p>Fórmula:C4H3ClN2O2Cor e Forma:NeatPeso molecular:146.532’,3’-Dideoxyinosine
CAS:Produto Controlado<p>Applications 2’,3’-Dideoxyinosine is a purine analog (1) which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2).<br>References 1. Esplugues, J. et al.: AIDS. 2016 Jun 1;30(9):1341-51.2. Blas-Garcia, A. et al.: J. Antimicrob. Chemother. 2016 Apr;71(4):916-26<br></p>Fórmula:C10H12N4O3Cor e Forma:NeatPeso molecular:236.23Cladribine
CAS:<p>Applications It is a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990);<br></p>Fórmula:C10H12ClN5O3Cor e Forma:White To Light YellowPeso molecular:285.692'-Deoxyadenosine Monohydrate
CAS:Produto Controlado<p>Applications 2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.<br>References Gordon, C., et al.: J. Med. Chem., 48, 1 (2005), Ikejiri, M., et al.: Bioorg. Med. Chem., 15, 6882 (2007),<br></p>Fórmula:C10H13N5O3·H2OCor e Forma:NeatPeso molecular:269.26Coenzyme Q9
CAS:<p>Applications Antibacterial and antioxidant for preventing and treating cancer.<br>References Itoh, K., et al.: J. Immunol., 170, 3688 (2003), Liu, A., et al.: J. Biol. Chem., 279, 53196 (2004), Wullaert, A., et al.: Biochem. Pharmacol., 72, 1090 (2006),<br></p>Fórmula:C54H82O4Cor e Forma:YellowPeso molecular:795.23Adenosine-15N
CAS:Produto Controlado<p>Applications Nitrogen 15 labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Fórmula:C10H1315NN4O4Cor e Forma:NeatPeso molecular:268.2354’,6-Diamidino-2-phenylindole Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A cell-permeable DNA-binding dye. Binds preferentially to DNA rich in adenine and thymine. Used in flow cytometry for measuring nuclear DNA content or for sorting isolated chromosomes.<br>References Jpeeesen, C, and Nielsen, P.E.: Eur. J. Biochem., 182, 437 (1989), Li,J., et al.: J. Exp. Biol., 200, 1499 (1997), Zaitsev, E.N., and Kowalczykowsi, S.C.: Nucl. Acids Res., 26(2), 650 (1998), Germ, M., et al.: Biochem. Biophys. Res. Commun., 261, 452 (1999),<br></p>Fórmula:C16H15N5·2ClHCor e Forma:Yellow PowderPeso molecular:350.25Dapagliflozin C2 Epimer
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Dapagliflozin C2 Epimer is an intermediate used in the synthesis of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Majewski, A., et al.: Przemysl Chemiczny, 95, 1129 (2016); Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO6Cor e Forma:NeatPeso molecular:408.87(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS:<p>Applications (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile is a predominant metabolite of remdesivir with great potential for Covid-19 treatment.<br>References Yan, V. C., et al.: ACS Med. Chem., 11, 1361 (2020)<br></p>Fórmula:C12H13N5O4Cor e Forma:NeatPeso molecular:291.2627Triethyl Methanetricarboxylate
CAS:Produto Controlado<p>Applications Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.<br>References Day, J. et al.: Chem. A Eur. J., 16, 2758 (2010); Sechi, M. et al.: Bioorg. Med. Chem., 17, 2925 (2009);<br></p>Fórmula:C10H16O6Cor e Forma:NeatPeso molecular:232.23Ammeline-13C3 Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isotope labelled Ammeline (A633660), which s a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Fórmula:C3H5N5O·ClHCor e Forma:NeatPeso molecular:166.54Adenosine-5'-13C
CAS:Produto Controlado<p>Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Fórmula:C913CH13N5O4Cor e Forma:NeatPeso molecular:268.24Penciclovir-d4
CAS:Produto Controlado<p>Applications A deuterated version of Penciclovir, an antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Fórmula:C102H4H11N5O3Cor e Forma:NeatPeso molecular:257.28Ribavirin Carboxylic Acid
CAS:<p>Impurity USP Ribavirin Related Compound A<br>Applications Ribavirin Carboxylic acid is an impurity of Ribavirin (R414475). Ribavirin impurity A.<br>References Lertora, J., et al.: Clin. Pharmacol. Ther., 50, 442 (1991), Connor, E., et al.: Antimicrob. Agents Chemother., 37, 532 (1993), Manns, M., et al.: Lancet, 358, 958 (2001),<br></p>Fórmula:C8H11N3O6Cor e Forma:NeatPeso molecular:245.19Adenosine-5',5''-d2
CAS:Produto Controlado<p>Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Fórmula:C10H11D2N5O4Cor e Forma:White SolidPeso molecular:269.26Abacavir Carboxylate
CAS:<p>Impurity Abacavir - In House Impurity<br>Stability Hygroscopic<br>Applications Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).<br>References (1) Hoetelmans, R., et al.: Pharm. World Sci., 19, 159 (1997) (2) Beach, J., et al.: Clin. Ther., 20, 2 (1998) (3) McDowell, J., et al.: Antimicrob. Agents Chemother., 43, 2855 (1999)<br></p>Fórmula:C14H16N6O2Cor e Forma:NeatPeso molecular:300.32Dapagliflozin Methyl Acetate
CAS:Produto Controlado<p>Applications Dapagliflozin Methyl Acetate is the impurity of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C23H27ClO7Cor e Forma:NeatPeso molecular:450.909L-Valacyclovir Hydrochloride
CAS:Produto Controlado<p>Applications Acyclovir (A192400) impurity. The L-Valine ester prodrug of Acyclovir.<br>References Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),<br></p>Fórmula:C13H20N6O4·ClHCor e Forma:White To Off-WhitePeso molecular:360.80Famciclovir-d4
CAS:Produto Controlado<p>Applications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral.<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Fórmula:C142H4H15N5O4Cor e Forma:Off-White To Light BeigePeso molecular:325.36N6-Isopentenyladenosine
CAS:<p>Applications N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells.<br>References Rajabi, M. et al.; DNA Cell Biol.; 29, 687 (2010)<br></p>Fórmula:C15H21N5O4Cor e Forma:NeatPeso molecular:335.365-Fluorodihydropyrimidine-2,4-dione-13C,15N2
CAS:Produto Controlado<p>Applications A labelled metabolite of 5-Fluorouracil (F596000).<br>References Bocci, G., et al.: Eur. J. Clin. Pharmacol., 58, 593 (2002), Longley, D.B., Nature Rev. Cancer, 3, 330 (2003), Fischel, J., et al.: Anti-Cancer Drugs, 15, 969 (2004)<br></p>Fórmula:C313CH5F15N2O2Cor e Forma:Off-White To Light BrownPeso molecular:135.071-α-Methyl Dapagliflozin
CAS:<p>Stability Hygroscopic<br>Applications 1α-Methyl Dapagliflozin is an antidiabetic agent and intermediate of Dapagliflozin (D226255]), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Fórmula:C22H27ClO7Cor e Forma:WhitePeso molecular:438.90Dapagliflozin
CAS:<p>Stability Hygroscopic<br>Applications A sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Fórmula:C21H25ClO6Cor e Forma:NeatPeso molecular:408.87Ribavirin 5’-Monophosphate Dilithium Salt (90%)
CAS:Produto Controlado<p>Applications A metabolite of Ribavirin.<br>References Allen, L.B., et al.: J. Med. Chem., 21, 742 (1978), Zimmerman, T., et al.: Biochem. Pharmacol., 27, 709 (1978), Page, T., et al.: Int. J. Biochem., 22, 379 (1990), Lin, C., et al.: Antimicrob. Agents Chemother., 47, 1395 (2003),<br></p>Fórmula:C17H19N4O9P·2LiPureza:90%Cor e Forma:Off-White To Light BeigePeso molecular:468.21O6-Benzylguanine
CAS:Produto Controlado<p>Applications An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.<br>References Dolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)<br></p>Fórmula:C12H11N5OCor e Forma:NeatPeso molecular:241.25α-Ribavirin (Ribavirin Impurity B)
CAS:Produto ControladoFórmula:C8H12N4O5Cor e Forma:NeatPeso molecular:244.203'-Azido-3'-deoxythymidine β-D-glucuronide, Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.<br></p>Fórmula:C16H20N5O10·NaCor e Forma:White To Light YellowPeso molecular:465.35Cabotegravir O-β-D-Glucuronide
CAS:Produto Controlado<p>Applications Cabotegravir O-β-D-Glucuronide is a metabolite of Cabotegravir (C050100), a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.<br>References Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, 397 (2015); Andrews, C. et al.: Sci. Transl. Med., 7, 270 (2015)<br></p>Fórmula:C25H25F2N3O11Pureza:>80%Cor e Forma:NeatPeso molecular:581.48Acyclovir Formacetal Dimer (>90%)
<p>Impurity Aciclovir EP Impurity R<br>Applications Acyclovir Formacetal Dimer is a dimer impurity of Acyclovir (A192400); an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also antiviral. (Aciclovir EP Impurity R)<br>References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)<br></p>Fórmula:C17H22N10O6Pureza:>90%Cor e Forma:NeatPeso molecular:462.422’-Deoxyadenosine
CAS:<p>Applications 2prime-Deoxyadenosine is a nucleoside adenosine derivative with mutagenic properties.<br></p>Fórmula:C10H13N5O3Cor e Forma:White To Off-WhitePeso molecular:251.242N-Nitrosodiethylamine (100 ug/mL in Methanol)
CAS:Produto ControladoFórmula:C4H10N2OCor e Forma:Single SolutionPeso molecular:102.14Famciclovir
CAS:Produto Controlado<p>Applications Used as an antiviral. Prodrug of Penciclovir (P221500).<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Fórmula:C14H19N5O4Cor e Forma:Off-WhitePeso molecular:321.33Peramivir
CAS:<p>Peramivir is a neuraminidase inhibitor used to treat influenza by preventing virus release from cells.</p>Fórmula:C15H28N4O4Pureza:99.82%Cor e Forma:SolidPeso molecular:328.41Coenzyme A Trilithium Salt
CAS:<p>Stability Hygroscopic<br>Applications A cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.<br>References Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010); Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968);<br></p>Fórmula:C21H33N7O16P3S·3LiCor e Forma:NeatPeso molecular:785.33Ribavirin-13C5
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Ribavirin (R414475). Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Fórmula:C5C3H12N4O5Cor e Forma:NeatPeso molecular:249.17N-Carbamoyl-2-fluoro-(β)-alanine
CAS:Produto Controlado<p>Applications A metabolite of Capecitabine.<br>References Arellano, M., ET AL.: Br. J. Cancer, 77, 79 (1998), Budman, D., ET AL.: J. Clin. Oncol., 16, 1795 (1998), Khanna, R., et al.: Cancer Res., 60, 4725 (2000), Charasson, V., et al.: Drug Metab. Dispos., 30, 731 (2002),<br></p>Fórmula:C4H7FN2O3Cor e Forma:NeatPeso molecular:150.116,6'-Thiobis-9H-purine
CAS:Produto Controlado<p>Applications 6,6'-Thiobis-9H-purine is used in the study of the activity of topoisomerase IIα.<br>References Jensen, L.H., et al.: Molecular Pharmacology, 70, 1503 (2006);<br></p>Fórmula:C10H6N8SCor e Forma:NeatPeso molecular:270.27Adenosine-1'-13C
CAS:Produto ControladoFórmula:CC9H13N5O4Cor e Forma:White To Off-WhitePeso molecular:268.234Adenosine 5'-Triphosphate Disodium Salt
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications A metabolite of Adenosine (A280400), a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism.<br>References Knowles, J., et al.: Annu. Rev. Biochem., 49, 877 (1980),<br></p>Fórmula:C10H14N5O13P3·2NaCor e Forma:NeatPeso molecular:569.162’-Deoxy Cytidine-5,6-d2
CAS:Produto ControladoFórmula:C9D2H11N3O4Cor e Forma:NeatPeso molecular:229.23Hypoxanthine
CAS:Produto Controlado<p>Applications A naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine Chemicals<br>References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),<br></p>Fórmula:C5H4N4OCor e Forma:NeatPeso molecular:136.11Ademethionine 1,4-Butanedisulfonate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.<br></p>Fórmula:C15H22N6O5S·3C4H10O6S2Cor e Forma:NeatPeso molecular:1451.62epi-Canagliflozin
CAS:Produto Controlado<p>Applications epi-Canagliflozin is an epimeric impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity.<br>References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);<br></p>Fórmula:C24H25FO5SCor e Forma:NeatPeso molecular:444.52(1R,2R,5R)-2-Isopropyl-5-methylcyclohexanol
CAS:<p>Applications (1R,2R,5R)-2-Isopropyl-5-methylcyclohexanol is used in the tetrahydropyranylation of alcohols.<br>References Magyar, A. et al.: Catal. Lett., 145, 1876 (2015);<br></p>Fórmula:C10H20OCor e Forma:NeatPeso molecular:156.27
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