Sulfonamidas e Derivados
As sulfonamidas são compostos que contêm um grupo funcional sulfonamida (-SO₂NH₂), onde um átomo de enxofre está ligado a um grupo amino. Foram um dos primeiros antibióticos sintéticos usados na medicina, inibindo a síntese do ácido fólico nas bactérias, o que lhes confere propriedades antimicrobianas. São utilizadas principalmente para tratar infeções bacterianas, embora seu uso tenha diminuído devido à resistência antimicrobiana. Além do uso como antibióticos, as sulfonamidas também têm aplicações no tratamento de doenças como a malária e doenças inflamatórias intestinais.
Na CymitQuimica, oferecemos sulfonamidas e seus derivados com alto grau de pureza para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 2587 produtos de "Sulfonamidas e Derivados"
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2,7-Diamino-6-phenyl-4-pteridinol
CAS:Produto Controlado<p>Impurity Triamterene EP Impurity B/ Triamterene USP Related Compound B<br>Applications 2,7-Diamino-6-phenyl-4-pteridinol has potential as a pteridine diuretic. Impurity in the synthesis of Triamterene (T767325), a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.<br>References Osdene, et al.: J. Med. Chem., 10, 431 (1967), Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 23, 571 (1994); Weinstock, J. et al.: J. Med. Chem., 11, 573 (1968);<br></p>Fórmula:C12H10N6OCor e Forma:NeatPeso molecular:254.25Mordant Yellow 10 (Technical Grade)
CAS:Produto Controlado<p>Impurity Sulfasalazine Impurity I<br>Stability Light Sensitive<br>Applications Mordant Yellow 10 is a monoazo dye used in wool textiles. Mordant Yellow 10 is used as organic reagent for spectrometric determination of iron(III) as well as in the study of other metal complexations.<br>References Ledneva, I.A. Izvest. Vyssh. Ucheb. Zav. Tekh. Teks. Prom., 5, 58 (1986); Vladescu, L. et al.: Rev. Roum. Chem., 54, 85 (2009); Gupta, P.N. et al.: Asian J. Chem., 4, 15 (1992);<br></p>Fórmula:C13H8N2O6S·2NaCor e Forma:NeatPeso molecular:366.264-Acetaminophen-d3 Sulfate
CAS:Produto Controlado<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Fórmula:C82H3H6NO5SCor e Forma:White To Off-WhitePeso molecular:234.243-Hydroxyacetaminophen
CAS:Produto Controlado<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C8H9NO3Cor e Forma:NeatPeso molecular:167.16(3RS)-1,3-Bis[4,-2-(methylpropyl)phenyl]butan-1-one
CAS:Produto ControladoFórmula:C24H32OCor e Forma:Colourless To Light YellowPeso molecular:336.51Tolbutamide-d9
CAS:Produto ControladoFórmula:C122H9H9N2O3SCor e Forma:White To Off-WhitePeso molecular:279.40Sulfathiazole
CAS:Produto Controlado<p>Applications Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 22, 389 (1993),<br></p>Fórmula:C9H9N3O2S2Cor e Forma:WhitePeso molecular:255.325-Amino-1,3,4-thiadiazole-2-sulfonamide Hydrochloride Salt
CAS:Produto Controlado<p>Impurity Acetazolamide EP Impurity D Hydrochloride<br>Applications Acetazolamide intermediate. (Acetazolamide EP Impurity D Hydrochloride)<br>References Carta, F., et al.: Bioorg. Med. Chem. Lett., 19, 6649 (2009), Joseph, P., et al.: J. Med. Chem., 53, 2277 (2010), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Fórmula:C2H5ClN4O2S2Cor e Forma:NeatPeso molecular:216.67Trimethoprim-d3
CAS:Produto Controlado<p>Applications Deuterated Trimethoprim, an antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C14D5H15N4O3Cor e Forma:Off WhitePeso molecular:297.3643-Oxo-1,2-benzoisothiazoline-2-acetic Acid Methyl Ester 1,1-Dioxide
CAS:<p>Impurity Piroxicam EP Impurity D<br>Applications Piroxicam impurity D.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C10H9NO5SCor e Forma:NeatPeso molecular:255.25Ibuprofen Alcohol
CAS:Produto Controlado<p>Applications Ibuprofen Alcohol (Ibuprofen EP Impurity P) is an impurity of Ibuprofen (I140000). Ibuprofen impurity P as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Fórmula:C13H20OCor e Forma:Colourless To Light YellowPeso molecular:192.306,6'-Oxybis-2-naphthalenesulfonic Acid Disodium Salt (>85%)
CAS:Produto Controlado<p>Applications An impurity contained in the commercial food Yellow No.5 (Sunset Yellow FCF) which has a potent mutagenicity effect.<br>References Yamada, M., et al.: Chem. Pharm. Bull., 44, 1624 (1996), Yamada, M., et al.: J. Food Chem., 3, 151 (1996),<br></p>Fórmula:C20H12O7S2·2NaPureza:>90%Cor e Forma:White To Light GreyPeso molecular:474.41Glimepiride
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993),<br></p>Fórmula:C24H34N4O5SCor e Forma:NeatPeso molecular:490.624-Nitro Sulfamethoxazole
CAS:Produto Controlado<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Fórmula:C10H9N3O5SCor e Forma:Light BrownPeso molecular:283.263-Desmethyl Trimethoprim
CAS:Produto Controlado<p>Applications 3-Desmethyl Trimethoprim is a metabolite of Trimethoprim (T795615); an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-Desmethyl Trimethoprim gets excreted in the urine of rats, dogs, and man in the form of glucuronides.<br>References Roth, B., et al.: J. Med. Chem., 24, 933 (1981); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Schwartz, D. E., Arzneimittel-Forsch., 20, 1867 (1970)<br></p>Fórmula:C13H16N4O3Cor e Forma:White To Light BrownPeso molecular:276.29Diacetic Aceclofenac
CAS:Produto Controlado<p>Impurity Aceclofenac EP Impurity H<br>Applications A 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent. (Aceclofenac EP Impurity H)<br></p>Fórmula:C20H17Cl2NO8Cor e Forma:White To Off-WhitePeso molecular:470.26Terizidone
CAS:Produto Controlado<p>Applications A drug used to treat tuberculosis.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>Fórmula:C14H14N4O4Cor e Forma:NeatPeso molecular:302.294-Hydroxy Trimethoprim
CAS:<p>Applications Trimethoprim (T795615) derivative. Antibacterial properties.<br></p>Fórmula:C14H18N4O4Cor e Forma:NeatPeso molecular:306.32Pyroxasulfone
CAS:Produto Controlado<p>Applications Pyroxasulfone is an inhibitor of the biosynthesis of very-long-chain fatty acids. Pyroxasulfone is also used to control grass weed species in pre-emergence in major field crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Busi, R., et al.: Pest. Manag. Sci., 72, 1665 (2016)<br></p>Fórmula:C12H14F5N3O4SCor e Forma:WhitePeso molecular:391.31Napropamid
CAS:<p>Applications Napropamid is used as a pesticide.<br>References She-feng, J., et al.: Nanjing Nongye Daxue Xuebao, 35, 137 (2012);<br></p>Fórmula:C17H21NO2Cor e Forma:Light Orange Color To Light BrownPeso molecular:271.35Phenacetin
CAS:Produto Controlado<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Fórmula:C10H13NO2Cor e Forma:WhitePeso molecular:179.22Despyridyl Piroxicam (Piroxicam Impurity C)
CAS:Produto ControladoFórmula:C10H10N2O4SCor e Forma:NeatPeso molecular:254.261,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester
CAS:<p>Impurity Etodolac EP Impurity K<br>Applications 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester (Etodolac EP Impurity K) is a derivative of Etodolac.<br>References Caldwell, J., et al.: Biochem. Pharmacol., 37, 105 (1988), Drummer, O., et al.: J. Anal. Toxicol., 17, 225 (1993)<br></p>Fórmula:C18H23NO3Cor e Forma:White To Off-WhitePeso molecular:301.38Diclosan
CAS:<p>Applications Diclosan is used in the treatment of halogenated phenolic compounds by sequential tri-metal reduction and laccase-catalytic oxidation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dai, Y., et al.: Water Res., 71, 64 (2015);<br></p>Fórmula:C12H8Cl2O2Cor e Forma:White PowderPeso molecular:255.10Acetanilide (Acetylaniline)
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Fórmula:C8H9NOCor e Forma:White To Light BrownPeso molecular:135.16Furosemide
CAS:Produto Controlado<p>Applications Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic. Non-competitve subtype-specific blocker of GABAA. Neuroprotective & Neuroresearch Products.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979); Korpi, E. et al.: Mol. Pharmacology, 47, 283 (1995);<br></p>Fórmula:C12H11ClN2O5SCor e Forma:White To Off-WhitePeso molecular:330.74Niflumic Acid
CAS:Produto Controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H9F3N2O2Cor e Forma:Light YellowPeso molecular:282.22Ibuprofen Carboxylic Acid(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.<br>References Bhuyan, K., et al.: Life Sci., 38, 1463 (1986), Blakytny, R., et al.: Biochem. J., 288, 303 (1992),Ganea, E., et al.: Eur. J. Biochem., 231, 181 (1995), Mitchell, J., et al.: Br. J. Pharmacol., 128, 1121 (1999),<br></p>Fórmula:C13H16O4Cor e Forma:White SolidPeso molecular:236.264-Acetamidobenzenesulfonic Acid
CAS:Produto Controlado<p>Impurity Sulfadimethoxine EP Impurity C<br>Stability Hygroscopic<br>Applications 4-Acetamidobenzenesulfonic Acid (Sulfadimethoxine EP Impurity C) is a metabolite of Sulfanilic acid.<br>References Saab, N., et al.: Eur. J. Med. Chem., 34, 745 (1999), Kim, H., et al.: J. Pharm. Biomed. Anal., 27, 51 (2002), Santelli-Rouvier, C., et al.: Eur. J. Med. Chem., 39, 735 (2004),<br></p>Fórmula:C8H9NO4SCor e Forma:NeatPeso molecular:215.23Benzylhydrochlorothiazide
CAS:Produto ControladoFórmula:C14H14ClN3O4S2Cor e Forma:NeatPeso molecular:387.86Hydroflumethiazide-13CD2
CAS:Produto Controlado<p>Applications Labelled Hydroflumethiazide. Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C713CH6D2F3N3O4S2Cor e Forma:NeatPeso molecular:334.30rac 1-Nitroso-2-methylindoline
CAS:Produto ControladoFórmula:C9H10N2OCor e Forma:BrownPeso molecular:162.19N-Nitroso Furosemide ( >80%)
CAS:Fórmula:C12H10ClN3O6SPureza:>80%Cor e Forma:Light Orange To Dark OrangeMethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
CAS:Produto Controlado<p>Impurity Piroxicam EP Impurity G<br>Applications Piroxicam impurity G.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Pharmacol., 36, 79 (1996), Bihovsky, R., et al.: Bioorg. Med. Chem. Lett., 14, 1035 (2004),<br></p>Fórmula:C10H9NO5SCor e Forma:NeatPeso molecular:255.254-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone
CAS:Produto Controlado<p>Impurity USP Trimethoprim Related Compound A<br>Applications 6-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone, is an impurity of Trimethoprim (T795615), an antibacterial agent.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Fórmula:C14H17N3O4Cor e Forma:WhitePeso molecular:291.30Glimepiride-d5
CAS:Produto Controlado<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneimittel-Forsch., 43, 856, (1993),<br></p>Fórmula:C24H29D5N4O5SCor e Forma:Off-WhitePeso molecular:495.65Dehydro Indapamide
CAS:Produto Controlado<p>Impurity Indapamide USP Related Compound A/ Indapamide EP Impurity B<br>Applications A metabolite of Indapamide (M5). A dehydrogenation pathway by cytochromes P450. Indapamide USP Related Compound A<br>References Tamura A., et al.: Chem. Pharm. Bull., 38, 225 (1990), Harlow, G.R., et al.: J. Biol. Chem., 272, 5396 (1997), Ozden, T., et al.: Pharm. Pharmacol. Commun., 4, 397 (1998), Gruciani, G., et al.: J. Med. Chem., 48, 6970 (2005), Sun, H., et al.: Drug. Metab. Dispos., 37, 672 (2009),<br></p>Fórmula:C16H14ClN3O3SCor e Forma:White To Light BrownPeso molecular:363.823-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid
CAS:<p>Impurity Bumetanide Impurity A<br>Applications 3-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid is a compound related to Piretanide (P508700) and an intermediate in the production of Bumetanide, Bumetanide Impurity A (B689550).<br></p>Fórmula:C13H10N2O7SCor e Forma:NeatPeso molecular:338.29Ibuprofen Dimer
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity G<br>Applications Ibuprofen Dimer (Ibuprofen EP Impurity G) is a dimer impurity of Ibuprofen (I140000).<br></p>Fórmula:C26H32O4Cor e Forma:Light Orange ColourPeso molecular:408.53rac Ibuprofen-d3
CAS:Produto Controlado<p>Applications Labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C132H3H15O2Cor e Forma:Off-WhitePeso molecular:209.30Bis(4-hydroxyphenyl) Sulfone
CAS:Produto Controlado<p>Applications Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.<br>References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);<br></p>Fórmula:C12H10O4SCor e Forma:WhitePeso molecular:250.274-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
CAS:<p>Impurity Glimepiride EP Impurity B/ USP Glimepiride Related Compound B<br>Applications 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide (Glimepiride EP Impurity B) is an intermediate for the preparation of Glimepiride.<br></p>Fórmula:C16H21N3O4SCor e Forma:Off-WhitePeso molecular:351.42N,N-Dimethylnicotinamide-2-sulfonamide
CAS:Produto Controlado<p>Applications N,N-Dimethylnicotinamide-2-sulfonamide (cas# 112006-75-4) is a compound useful in organic synthesis.<br></p>Fórmula:C8H11N3O3SCor e Forma:NeatPeso molecular:229.262-Amino-5-chlorobenzenesulfonamide
CAS:Produto Controlado<p>Applications 2-Amino-5-chlorobenzenesulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).<br>References Cannazza, G., et. al.: Bioorg. Med. Chem. Lett., 19, 1254 (2009); Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995); Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999); Sun, Y., et al.: Nature, 417, 245 (2002); Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006)<br></p>Fórmula:C6H7ClN2O2SCor e Forma:NeatPeso molecular:206.65Indomethacin Diamide
CAS:Produto Controlado<p>Applications Indomethacin Diamide is an impurity of Indomethacin (I641000), an non-steroidal anti-inflammatory drug commonly used in the treatment of fever, pain and swelling.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C33H27Cl2N3O5Cor e Forma:NeatPeso molecular:616.49Hydrochlorothiazide-13C,15N2,d2
CAS:Produto Controlado<p>Applications Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981),<br></p>Fórmula:C613CH6D2ClN15N2O4S2Cor e Forma:NeatPeso molecular:302.73
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