Leucovorin calcium salt - Bio-X ™

CAS: 1492-18-8

Ref. 3D-BC164621

Informação sobre produto

• Nome: Leucovorin calcium salt - Bio-X ™
• Sinónimos: Leucovorin Calcium, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), Calcium 5-formyltetrahydrofolate, Calcium <span class="text-smallcaps">L</span>-folinate, Calcium Folinate, Calcium Folinate(Folinic Acid)(Rg), Calcium L-Folinate, Calcium leucovorin, Calcium2-[4-[(2-Amino-5-Formyl-4-Oxo-1,6,7,8-Tetrahydropteridin-6-Yl)Methylamino]Benzoyl] Aminopentanedioate, Calciumfolinat, Folidan, Folinate De Calcium, Folinate-SF calcium, Folinato Calcico, Folinic acid Calcium salt, Folinic acid calcium salt USP28, Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), <span class="text-smallcaps">L</span>-, Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), L-, L-Calcium Folinate, L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), Lederfoline, Leucovorin calcium salt, LeucovorinCalcium, Leucovorine calcium, Nsc 3590, Rescuvolin, Wellcovorin, calcium (2S)-2-({[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}amino)pentanedioate, calcium (2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl)amino]pentanedioate

Descrição

Leucovorin is a folate analog drug that is used to treat the toxic effects of methotrexate and other antagonists of folate. It works by counteracting the toxic effects of methrotrexate by inhibiting the enzyme dihydrofolate reductase. It is used to increase the levels of folic acid and by strengthening the link between the active metabolite (5-FdUMP) and the enzyme thymidylate synthetase, leucovorin increases the action of fluorouracil. Additionally, in order to increase survival in patients undergoing palliative treatment for colorectal cancer, it is used in conjunction with 5-fluorouracil.

Leucovorin calcium salt is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 513.52 g/mol
• Fórmula: C₂₀H₂₃N₇O₇·Ca
• Pureza: Min. 95%
• Cor/forma: Powder