Adarotene
CAS: 496868-77-0
Ref. 3D-FA175281
1mg | Descontinuado | ||
2mg | Descontinuado | ||
5mg | Descontinuado | ||
10mg | Descontinuado | ||
25mg | Descontinuado |
Informação sobre produto
- (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
- (2E)-3-(4′-Hydroxy-3′-tricyclo[3.3.1.1<sup>3,7</sup>]dec-1-yl[1,1′-biphenyl]-4-yl)-2-propenoic acid
- (E)-3-[4-[3-(1-Adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid
- 2-Propenoic acid, 3-(4′-hydroxy-3′-tricyclo[3.3.1.1<sup>3,7</sup>]dec-1-yl[1,1′-biphenyl]-4-yl)-, (2E)-
- 3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid
- St 1926
Adarotene is a cytosolic calcium ionophore that has potent inducers of chemiluminescence. It is a synthetic retinoid that binds to the nuclear retinoid receptor and induces transcription of genes. Adarotene has been shown to inhibit cancer cell proliferation, induce apoptosis, and act as an anti-cancer compound. The polymerase chain reaction (PCR) technique has been used to measure adarotene concentration in t-cell lymphomas. Adarotene is toxic to cells and causes cellular physiology changes by altering mitochondrial membrane potential.