4-Amino-3-fluorobenzonitrile

CAS: 63069-50-1

Ref. 3D-FA64109

Informação sobre produto

• Nome: 4-Amino-3-fluorobenzonitrile
• Sinónimos: 2,2,3,3,4,4-Hexafluoropentane-1,5-Diyl Bis(4-Methylbenzenesulfonate), 2-Fluoro-4-cyanoaniline, 3-Fluoro-4-aminobenzonitrile, 4-Amino-3-fluorobenzenecarbonitrile, 4-Cyano-2-fluoroaniline, Benzonitrile, 4-amino-3-fluoro-

Descrição

4-Amino-3-fluorobenzonitrile is an agonist of the DPP-4 enzyme. It has been shown to decrease blood glucose levels in a rat model. 4-Amino-3-fluorobenzonitrile binds to the active site of DPP-4, increasing its activity and inhibiting the breakdown of incretin hormones such as glucagon-like peptide 1 (GLP1) and glucose-dependent insulinotropic polypeptide (GIP). 4-Amino-3-fluorobenzonitrile inhibits glucagon secretion from pancreatic alpha cells, which leads to a decrease in blood glucose levels. The compound also inhibits GLP1 secretion from intestinal L cells, leading to decreased appetite and weight loss. 4-Amino-3-fluorobenzonitrile has been shown to be an agonist with biphenyl, which may explain its agonistic activity.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 136.13 g/mol
• Fórmula: C₇H₅FN₂
• Pureza: Min. 95%
• Cor/forma: Powder