4-(Trifluoromethoxy)phenyl isocyanate

CAS: 35037-73-1

Ref. 3D-FT00399

Informação sobre produto

• Nome: 4-(Trifluoromethoxy)phenyl isocyanate
• Sinónimos: TOPIC, 1-Isocyanato-4-(Trifluoromethoxy)-Benzen, 1-Isocyanato-4-(Trifluoromethoxy)Benzene, 4-(Trifluoromethoxy)Phnyl Isocyanate, 4-Trifluoromethoxy Phenylisocyanate, 4-Trifluromethoxylphenylisocyanate, Benzene, 1-isocyanato-4-(trifluoromethoxy)-, Isocyanato-4-(trifluoromethoxy)benzene, P-(Trifluoromethoxy)Phenyl Isocyanate, 4-(Trifluoromethoxy) phenyl isocyanate

Descrição

4-(Trifluoromethoxy)phenyl isocyanate (4-TFPC) is a potent antagonist of the platelet P2Y12 receptor. It inhibits platelet aggregation and adhesion, as well as prevents the formation of blood clots. 4-TFPC has a low molecular weight and can be administered orally. It also has been shown to increase insulin sensitivity and reduce blood glucose levels in mice with type 2 diabetes. This antiplatelet agent binds to receptors on the surface of platelets, preventing activation. 4-TFPC is also an inhibitor of protein kinase C and phosphodiesterases, which are enzymes that regulate cell signalling pathways. In vitro studies have shown that 4-TFPC inhibits cycloheptyl (CPH)-induced aggregation in human platelets in a dose-dependent manner with an IC50 value of 0.5 μM.END>

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 203.12 g/mol
• Fórmula: C₈H₄F₃NO₂
• Pureza: Min. 95%
• Cor/forma: Colorless Clear Liquid
• InChI: InChI=1S/C8H4F3NO2/c9-8(10,11)14-7-3-1-6(2-4-7)12-5-13/h1-4H
• Chave InChI: InChIKey=LGPKFIGMLPDYEA-UHFFFAOYSA-N
• SMILES: O=C=Nc1ccc(OC(F)(F)F)cc1