8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt

CAS: 129735-00-8

Ref. 3D-NB13568

Informação sobre produto

• Nome: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt
• Sinónimos: Rp-8-Br-cAMPS, Rp-8-Br-Camps, Rp-8-Br-Camps, Na, Rp-8-Br-Camps Sodium Salt, 8-Bromoadenosine-3’,5’-Cyclicmonophosphorothioate,Rp-Isomer(Rp-8-Br-Camps),Sodiumsalt, 8-Bromoadenosine-3',5'-Cyclic Monophosphorothioate Sodium Salt, Rpisomer, 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate, Rp-Isomer Sodium Salt, 8-Br-Camps Na, Rp-Isomer

Descrição

8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt (8-BrAMP) is an activated analog of adenosine that binds to the cyclase enzyme and inhibits its activity. It has been shown to inhibit the production of epidermal growth factor in a model system. 8-BrAMP also blocks the synthesis of cyclic nucleotides by inhibiting cyclic nucleotide phosphodiesterase, which results in increased levels of cAMP. 8-BrAMP has been shown to inhibit HIV infection by acting as a transcription-polymerase chain inhibitor and blocking HIV mRNA synthesis. The drug also inhibits cell lysis by binding to calmodulin and β-catenin.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 447.16 g/mol
• Fórmula: C₁₀H₁₁BrN₅O₅PS·Na
• Pureza: Min. 95%
• Cor/forma: White/Off-White Solid