DPP IV Inhibitor, NVP DPP 728

CAS: 247016-69-9

Ref. 3D-XJA01669

Informação sobre produto

• Nome: DPP IV Inhibitor, NVP DPP 728
• Sinónimos: NVP-DPP 728, 3-Pyridinecarbonitrile, 6-[[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino]-, 2-Pyrrolidinecarbonitrile, 1-[[[2-[(5-cyano-2-pyridinyl)amino]ethyl]amino]acetyl]-, (2S)-, 6-[[2-[[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino]-3-pyridinecarbonitrile, (2S)-1-[2-[[2-[(5-Cyano-2-pyridyl)amino]ethyl]amino]acetyl]pyrrolidine-2-carbonitrile

Descrição

DPP IV Inhibitor, NVP DPP 728 is a small molecule with a molecular weight of 473.6 g/mol that has the biological function of inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). It is a cavity-forming agent with a fatty acid moiety and an amine group. It binds to the active site of DPP-4, which is located in the lumenal side of the cell membrane, and inhibits its action by binding to its catalytic site. This product has been shown to have high chemical stability and can be taken orally without causing gastrointestinal distress. Pharmacokinetic properties have been evaluated in both humans and rats. The drug has a good oral bioavailability, long half-life, and low clearance rate in humans, while it is rapidly absorbed from the intestine and eliminated through urine in rats.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 371.27 g/mol
• Fórmula: C₁₅H₁₈N₆O·2HCl
• Pureza: Min. 95%