(S)-4-(Benzhydryloxy)-2-hydroxy-N,N,N-trimethyl-4-oxobutan-1-aminium Chloride

Ref. TR-B196985

Informação sobre produto

• Nome: (S)-4-(Benzhydryloxy)-2-hydroxy-N,N,N-trimethyl-4-oxobutan-1-aminium Chloride

Descrição

Applications (S)-4-(Benzhydryloxy)-2-hydroxy-N,N,N-trimethyl-4-oxobutan-1-aminium Chloride is an intermediate in the synthesis of 3-Hydroxy-9-hexadecenoyl-L-carnitine which is an analogue of 3-Hydroxyhexadecanoylcarnitine Inner Salt (H943005), a derivative of Carnitine, essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado. Also 3-Hydroxyhexadecanoylcarnitine works similar to the endogenous non-toxic molecule L-Carnitine (C184110) whose bioavailablity is improved due to the transport systems in place for Carnitine.
References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978), Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001), Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002), Karlic, H., et al.: Nutrition, 20, 709 (2004), O. Piermatti. et al.: Bioorg. Med. Chem., 16, 1444 (2008)

• Marca: TRC

Propriedades químicas

• Peso molecular: 363.88
• Fórmula: C₂₀H₂₆ClNO₃
• Cor/forma: Beige Solid
• InChI: InChI=1S/C20H26NO3.ClH/c1-21(2,3)15-18(22)14-19(23)24-20(16-10-6-4-7-11-16)17-12-8-5-9-13-17;/h4-13,18,20,22H,14-15H2,1-3H3;1H/q+1;/p-1/t18-;/m0./s1