Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone

CAS: 1534326-81-2

Ref. TR-B522610

Informação sobre produto

• Nome: Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
• Sinónimos: Methanone, bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-, Solifenacin Succinate Imp. C (EP)
• Marca: TRC
• Descrição: Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)

Propriedades químicas

• Peso molecular: 444.57
• Fórmula: C₃₁H₂₈N₂O
• Cor/forma: Neat
• InChI: InChI=1S/C31H28N2O/c34-31(32-21-19-23-11-7-9-17-27(23)29(32)25-13-3-1-4-14-25)33-22-20-24-12-8-10-18-28(24)30(33)26-15-5-2-6-16-26/h1-18,29-30H,19-22H2/t29-,30-/m0/s1
• Chave InChI: InChIKey=CAQGZNDDACGLPT-KYJUHHDHSA-N
• SMILES: O=C(N1CCc2ccccc2[C@@H]1c1ccccc1)N1CCc2ccccc2[C@@H]1c1ccccc1