(3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]-2-oxetanone

CAS: 68711-40-0

Ref. TR-H296535

Informação sobre produto

• Nome: (3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]-2-oxetanone
• Sinónimos: (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one

Descrição

Applications (3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]-2-oxetanone is an analog of Tetrahydrolipstatin, an inhibitor of the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG), also an intermediate in the preparation of Orlistat (O686500).
References Mechoulam, R., et al.: Biochem. Pharmacol., 50, 83 (1995), Bisogno, T., et al.: J. Cell Biol., 163, 463 (2003), Di Marzo, V., et al.: Nat. Rev. Drug Discovery, 7, 438 (2008), Ortar, G., et al.: J. Med. Chem., 51, 6970 (2008),

• Marca: TRC

Propriedades químicas

• Peso molecular: 354.57
• Fórmula: C₂₂H₄₂O₃
• Cor/forma: Neat
• InChI: InChI=1S/C22H42O3/c1-3-5-7-9-10-11-12-13-14-16-19(23)18-21-20(22(24)25-21)17-15-8-6-4-2/h19-21,23H,3-18H2,1-2H3/t19-,20-,21-/m0/s1
• Chave InChI: InChIKey=RSOUWOFYULUWNE-ACRUOGEOSA-N
• SMILES: CCCCCCCCCCC[C@H](O)C[C@@H]1OC(=O)[C@H]1CCCCCC