4-Hydroxy Nebivolol, Hydrochloride Hydrate(Mixture of Diastereomers)

CAS: 178383-76-1

Ref. TR-H948530

Informação sobre produto

• Nome: 4-Hydroxy Nebivolol, Hydrochloride Hydrate(Mixture of Diastereomers)
• Sinónimos: 6-Fluoro-α-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino]methyl]-3,4-dihydro-4-hydroxy-2H-1-benzopyran-2-methanol Hydrochloride Hydrate
• Marca: TRC
• Descrição: Stability HygroscopicApplications A metabolite of Nebivolol.References Stoleru, L., et al.: J. Cardiovasc. Pharmacol., 22, 183 (1993), Cockcroft, J., et al.: J. Pharmacol. Exp. Ther., 274, 1067 (1995), Stoschitzky, K., et al.: Cardiovasc. Drugs Ther., 16, 133 (2002), Poole-Wilson, P., et al.: Lancet, 362, 7 (2003),

Propriedades químicas

• Peso molecular: 475.91
• Fórmula: C₂₂H₂₈ClF₂NO₆
• Cor/forma: Neat
• InChI: InChI=1S/C22H25F2NO5.ClH.H2O/c23-13-2-5-19-12(7-13)1-4-21(29-19)17(27)10-25-11-18(28)22-9-16(26)15-8-14(24)3-6-20(15)30-22;;/h2-3,5-8,16-18,21-22,25-28H,1,4,9-11H2;1H;1H2
• Chave InChI: InChIKey=NNLYRGGZJNHZRC-UHFFFAOYSA-N
• SMILES: Cl.O.OC1CC(C(O)CNCC(O)C2CCc3cc(F)ccc3O2)Oc2ccc(F)cc21