CAS 1000770-96-6

Formel: C50H80N6O8

InChl: InChI=1S/C50H80N6O8/c1-14-17-23-34(8)29-39-47(60)54(11)36(10)50(63)64-43(22-16-3)46(59)53-40(30-35(9)24-18-15-2)49(62)55(12)41(28-33(6)7)44(57)51-38(27-32(4)5)48(61)56(13)42(45(58)52-39)31-37-25-20-19-21-26-37/h3,19-21,25-26,32-36,38-43H,14-15,17-18,22-24,27-31H2,1-2,4-13H3,(H,51,57)(H,52,58)(H,53,59)/t34-,35-,36+,38+,39+,40+,41+,42+,43-/m1/s1

InChI Key: FKOWLFBDYYDNSC-ASFFCJJISA-N

SMILES: CCCC[C@@H](C)C[C@H]1C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N1)CC#C)C)C)C[C@H](C)CCCC)CC2=CC=CC=C2)C)CC(C)C)CC(C)C)C

CT-08

CAS: 1000770-96-6

CT-08 (CT8, Compound 3) is a macrolide Sec61 modulator that inhibits protein secretion in a signal sequence-dependent manner. It prevents the Sec61-mediated translocation of VCAMss-GLuc to the ER, resulting in the loss of luciferase activity. Additionally, CT-08 suppresses the expression of VCAM in transfected cells.

Formel: C₅₀H₈₀N₆O₈

Farbe und Form: Solid

Molekulargewicht: 893.206

Ref: TM-TP3082