CAS 1024583-85-4

Formel: C18H25N3O3

InChl: InChI=1S/C18H25N3O3/c1-18(2,3)24-17(23)20-9-6-10-21-12-13(11-16(19)22)14-7-4-5-8-15(14)21/h4-5,7-8,12H,6,9-11H2,1-3H3,(H2,19,22)(H,20,23)

InChI Key: HTWSTUSKTXEDDL-UHFFFAOYSA-N

SMILES: CC(C)(C)OC(=O)NCCCN1C=C(C2=CC=CC=C21)CC(=O)N

N-[3-[3-(2-Amino-2-oxoethyl)-1H-indol-1-yl]propyl]-carbamic Acid 1,1-Dimethylethyl Ester

Kontrolliertes Produkt

CAS: 1024583-85-4

Applications N-​[3-​[3-​(2-​Amino-​2-​oxoethyl)​-​1H-​indol-​1-​yl]​propyl]​-​carbamic Acid 1,​1-​Dimethylethyl Ester is an intermediate in synthesizing Bisindolylmaleimide III Hydrochloride (B448480), a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway.
References Jena, N.R., et al.: J. Molec. Model., 18, 631 (2012); Murphy, R.C., et al.: ACS. Med. Chem. Lett., 1, 331 (2010)

Formel: C₁₈H₂₅N₃O₃

Farbe und Form: Neat

Molekulargewicht: 331.41

Ref: TR-A616315