CAS 10538-99-5

Formel: C20H21N7O7

InChl: InChI=1S/C20H21N7O7/c21-19-24-15-14(17(31)25-19)27-11(7-22-15)8-26(20(27)34)10-3-1-9(2-4-10)16(30)23-12(18(32)33)5-6-13(28)29/h1-4,11-12H,5-8H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/t11?,12-/m0/s1

InChI Key: JSNFRYBHBVDHSG-KIYNQFGBSA-N

SMILES: C1C2CN(C(=O)N2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)N[C@@H](CCC(=O)O)C(=O)O

LY 345899

CAS: 10538-99-5

LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for

Formel: C₂₀H₂₁N₇O₇

Reinheit: 99.7%

Farbe und Form: Solid

Molekulargewicht: 471.4234

Ref: TM-T15827

LY 345899

CAS: 10538-99-5

LY 345899

Formel: C₂₀H₂₁N₇O₇

Reinheit: ≥98%

Molekulargewicht: 471.42

Ref: 54-BUP12893

LY 345899

CAS: 10538-99-5

Formel: C₂₀H₂₁N₇O₇

Reinheit: 97%

Farbe und Form: Solid

Molekulargewicht: 471.4234

Ref: IN-DA01FNFK

LY 345899

CAS: 10538-99-5

(2S)-2-(4-(3-Amino-1,9-dioxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl)benzamido)pentanedioic acid

Formel: C₂₀H₂₁N₇O₇

Reinheit: 97%

Molekulargewicht: 471.42

Ref: IN-DG271413

(2S)-2-(4-(3-Amino-1,9-dioxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl)benzamido)pentanedioic acid

CAS: 10538-99-5

Reinheit: 97%

Molekulargewicht: 471.4299927

Ref: 10-F869423

LY 345899

CAS: 10538-99-5

LY 345899 is a methyltransferase inhibitor that blocks the synthesis of fatty acid in cells. LY 345899 is used as an experimental drug for cancer treatment and other diseases. The mechanism of action of LY 345899 is not well understood, but it may involve regulating transcriptional regulation and protein synthesis in the mitochondria. Clinical trials have shown that LY 345899 has a clinical relevance in the treatment of cancer and autoimmune diseases.

Formel: C₂₀H₂₁N₇O₇

Reinheit: Min. 95%

Molekulargewicht: 471.42 g/mol

Ref: 3D-KAA53899