CAS 1094048-77-7

Formel: C17H12INO5

InChl: InChI=1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+

InChI Key: HSRMHXWCTRFVHK-NYYWCZLTSA-N

SMILES: COC1=C(C(=CC(=C1)/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)I)O

I-OMe-Tyrphostin AG 538

CAS: 1094048-77-7

I-OMe-Tyrphostin AG 538

Formel: C₁₇H₁₂INO₅

Reinheit: ≥95%

Molekulargewicht: 437.19

Ref: 54-BUP09174

I-OMe-Tyrphostin AG 538

CAS: 1094048-77-7

Ref: IN-DA024X6A

TYRPHOSTIN I-OME-AG 538

CAS: 1094048-77-7

2-(3,4-Dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile is a high purity ion channel inhibitor with IC50 of 1.8 nM. It has been shown to inhibit the activity of voltage gated sodium channels in rat hippocampal neurons and human erythrocytes. The binding affinity of 2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5 methoxyphenyl)prop-2 enenitrile for the nicotinic acetylcholine receptor (nAChR), as determined by competitive radioligand binding assay, is 21 pM. This compound also inhibits the activity of potassium channels and has been shown to bind to peptides and antibodies.

Formel: C₁₇H₁₂INO₅

Reinheit: Min. 95%

Molekulargewicht: 437.18 g/mol

Ref: 3D-UTB04877

I-OMe-Tyrphostin AG 538

CAS: 1094048-77-7

I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.

Formel: C₁₇H₁₂INO₅

Reinheit: 98.8%

Farbe und Form: Solid

Molekulargewicht: 437.19

Ref: TM-T11593