CAS 1095009-44-1

Formel: C32H43N11O15S2

InChl: InChI=1S/C32H43N11O15S2/c33-15-11-59-60-12-19(27(35)51)41-31(55)17(6-23(34)46)40-32(56)21-5-14(44)10-42(21)25(48)9-37-29(53)16(3-13-1-2-22(45)20(4-13)43(57)58)38-24(47)8-36-30(54)18(7-26(49)50)39-28(15)52/h1-2,4,14-19,21,44-45H,3,5-12,33H2,(H2,34,46)(H2,35,51)(H,36,54)(H,37,53)(H,38,47)(H,39,52)(H,40,56)(H,41,55)(H,49,50)/t14-,15-,16+,17+,18-,19-,21+/m1/s1

InChI Key: VALZMCWLPCJDLL-OPUINZJVSA-N

SMILES: C1[C@H](CN2[C@@H]1C(=O)N[C@H](C(=O)N[C@H](CSSC[C@H](C(=O)N[C@@H](C(=O)NCC(=O)N[C@H](C(=O)NCC2=O)CC3=CC(=C(C=C3)O)[N+](=O)[O-])CC(=O)O)N)C(=O)N)CC(=O)N)O

LXY3

CAS: 1095009-44-1

LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.

Formel: C₃₂H₄₃N₁₁O₁₅S₂

Farbe und Form: Solid

Molekulargewicht: 885.88

Ref: TM-TP3270