CAS 109838-85-9

(R)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazin

Formel: C₉H₁₆N₂O₂

InChl: InChI=1/C9H16N2O2/c1-6(2)8-9(13-4)10-5-7(11-8)12-3/h6,8H,5H2,1-4H3/t8-/m1/s1

SMILES: CC(C)[C@@H]1C(=NCC(=N1)OC)OC

Synonyme:

• (R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine
• (2R)-3,6-dimethoxy-2-(propan-2-yl)-2,5-dihydropyrazine
• (2R)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine
• 2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE
• (2R)-2,5-Dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazine
• BISLACTIMETHER
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE, 98+%
• (2R)-3,6-DIMETHOXY-2-(1-METHYLETHYL)-2,5-DIHYDROPYRAZINE
• (R)-2,5-DIMETHOXY-3-ISOPROPYL-3,6-DIHYDROPYRAZINE
• zR{-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• SCHOELLKOPF-HARTWIG-REAGENT
• (2R)-(-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine (aka (R )-Schollkopf reagent)
• (R)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPIPERAZINE
• (-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-Schollkopf Reagent
• Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-, (2R)-(9CI)

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine, 98%

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazineChiral auxiliary for the synthesis of -amino acids. It is an inhibitor with antitumor activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer

Formel: C₉H₁₆N₂O₂

Reinheit: 98%

Farbe und Form: Colorless to yellow to orang, Liquid

Molekulargewicht: 184.24

Ref: 02-H56077

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

Formel: C₉H₁₆N₂O₂

Reinheit: 97%

Farbe und Form: Liquid

Molekulargewicht: 184.2355

Ref: IN-DA0032ER

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

Formel: C₉H₁₆N₂O₂

Reinheit: >99%

Farbe und Form: Liquid

Molekulargewicht: 184.23553

Ref: 54-OR925455

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Formel: C₉H₁₆N₂O₂

Reinheit: >95.0%(GC)

Farbe und Form: Colorless to Yellow clear liquid

Molekulargewicht: 184.24

Ref: 3B-D3256

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine and its enantiomer (S)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine are also known as Schöllkopf chiral auxiliaries or Schöllkopf reagents, and are used to produce optically pure α-amino acids via asymmetric synthesis. The Schöllkopf reagent can be deprotonated at the prochiral α-carbon, and the resulting enolate is trapped with electrophiles to yield adducts with high (typically > 95% d.e.) diastereoselectivity. The enolate is essentially planar, and the steric bulk of the isopropyl group directs the incoming electrophile to attack from the opposite face, yielding trans adducts. A wide range of electrophiles including alkyl halides, alkyl sulfonates, acyl chlorides, aldehydes, ketones, epoxides, thioketones and enones can be used. Hydrolysis, typically under mild acidic conditions, yields the non-substituted amino acid with high (typically > 95 e.e.) enantiopurity.

Formel: C₉H₁₆N₂O₂

Reinheit: Min. 98%

Farbe und Form: Colorless Yellow Clear Liquid

Molekulargewicht: 184.24 g/mol

Ref: 3D-FD04039

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Reinheit: 96%

Molekulargewicht: 184.24

Ref: 10-F790908

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

Formel: C₉H₁₆N₂O₂

Reinheit: 97%

Molekulargewicht: 184.24

Ref: IN-DG47372

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine (>85% Purity)

Kontrolliertes Produkt

CAS: 109838-85-9

Stability Moisture Sensitive
Applications An inhibitor with antitumor activity.
References Plumb, J., et al.: Mol. Cancer Ther., 2, 721 (2003), de Ruijter, A., et al.: Biochem. J., 370, 737 (2003), Dey, P., et al.: Curr. Med. Chem., 13, 2909 (2006), Maiso, P., et al.: Cancer Res., 66, 5781 (2006), Paris, M., et al.: J. Med. Chem., 51, 1505 (2008),

Formel: C₉H₁₆N₂O₂

Reinheit: >85%

Farbe und Form: Neat

Molekulargewicht: 184.24

Ref: TR-I824430