CAS 113507-06-5
:Moxidectin
Beschreibung:
Moxidectin ist eine semi-synthetische makrocyclische Lacton, die zur Klasse der Verbindungen gehört, die als Avermectine bekannt sind, die aus der Fermentation des Bakteriums Streptomyces avermitilis gewonnen werden. Es wird hauptsächlich als antiparasitäres Mittel verwendet, insbesondere in der Tiermedizin, zur Behandlung verschiedener parasitärer Infektionen bei Tieren, einschließlich Nematoden und Ektoparasiten. Moxidectin zeigt ein breites Wirkungsspektrum und ist bekannt für seine lange Wirkungsdauer, die eine weniger häufige Dosierung im Vergleich zu anderen antiparasitären Mitteln ermöglicht. Die Verbindung wirkt, indem sie an glutamatgesteuerte Chloridkanäle im Nervensystem der Parasiten bindet, was zur Lähmung und zum Tod des Organismus führt. Moxidectin wird typischerweise oral oder durch Injektion verabreicht, und seine Pharmakokinetik ist durch eine gute Absorption und Verteilung in den Geweben gekennzeichnet. Es ist wichtig zu beachten, dass Moxidectin zwar gegen viele Parasiten wirksam ist, jedoch nicht gegen alle, und seine Anwendung sollte durch veterinärmedizinische Empfehlungen geleitet werden, um Sicherheit und Wirksamkeit zu gewährleisten.
Formel:C37H53NO8
InChl:InChI=1/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31-/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1
InChI Key:InChIKey=YZBLFMPOMVTDJY-LSGXYNIPSA-N
SMILES:C(=C\C(C)C)(\C)/[C@H]1O[C@@]2(C[C@@]3(C[C@](O2)(C/C=C(\C)/C[C@@H](C)/C=C/C=C\4/[C@@]5(O)[C@](C(=O)O3)(C=C(C)[C@@H](O)[C@]5(OC4)[H])[H])[H])[H])C/C(=N\OC)/[C@@H]1C
Synonyme:- (2aE,4E,4'E,5'S,6R,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-4'-(methoxyimino)-5',6,8,19-tetramethyl-6'-[(2E)-4-methylpent-2-en-2-yl]-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-2H,17H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-17-one
- (6R,23E,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)milbemycin B
- 23-Methoxime-LL-F 28249α
- 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
- Cl 301423
- Cydectin
- Equest
- Milbemycin B, 5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino)-, [6R,23E,25S(E)]-
- Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
- Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
- MilbemycinB
- Moxidextin
- ProHeart 6
- Proheart
- Quest
- Quest (parasiticide)
- Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], milbemycin B deriv.
- Vetdectin Oral Drench
- Moxidectin@100 μg/mL in Acetonitrile
- [6R,23E,25S(E)]-5-O-DeMethyl-28-deoxy-25-(1,3-diMethyl-1-butenyl)-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B
- Moxidectin powder CAS 113507-06-5 fiona
- Moxidectin Solution, 100ppm
- Moxidectin CRS
- Moxidectin
- (1R,4S,4'E,5'S,6R,6'S,8R,10E,13R,14E,16E,20R,21R,24S)-21,24-dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-[(E)-4-methylpent-2-en-2-yl]spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
- milbemycin B
- Moxidectin, >=98%
- (2R,2a'E,2a1'S,4Z,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-Dihydroxy-4-(methoxyimino)-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one
- Milbemycin B,
- Moxidectin for system suitability CRS
- Milbemycin B,5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-buten-1-yl)-6,28-epoxy-23-(methoxyimino)-,(6R,23E,25S)-
- Moxidectin,MilbeMycin B,23-MethoxiMe-LL-F 28249α,Equest,ProHeart 6
- Moxidectin Solution in Methanol, 100μg/mL
- Moxdectin
- (6R,23E,25S)-5-O-DeMethyl-28-deoxy-25-[(1E)-1,3-diMethyl-1-buten-1-yl]-6,28-epoxy-23-(MethoxyiMino)
- Moxidectin HOUSE STANDARD
- Weitere Synonyme anzeigen
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22 Produkte.
Moxidectin
CAS:Formel:C37H53NO8Reinheit:>98.0%(N)Farbe und Form:White to Almost white powder to crystalMolekulargewicht:639.83Moxidectin
CAS:MoxidectinFormel:C37H53NO8Reinheit:94.2%Farbe und Form:Off-WhiteMolekulargewicht:639.37712MOXIDECTIN CRS
CAS:<p>MOXIDECTIN CRS</p>Formel:C37H53NO8Farbe und Form:PowderMolekulargewicht:639.8186MOXIDECTIN FOR SYSTEM SUITABILITY CRS
CAS:<p>MOXIDECTIN FOR SYSTEM SUITABILITY CRS</p>Formel:C37H53NO8Farbe und Form:PowderMolekulargewicht:639.8186Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
CAS:Formel:C37H53NO8Reinheit:96%Farbe und Form:SolidMolekulargewicht:639.8186Moxidectin
CAS:<p>Moxidectin (CL301423) is an anthelmintic for heartworm/intestinal worms in dogs, cats, horses, cattle, and sheep; oral/topical/injectable.</p>Formel:C37H53NO8Reinheit:97.38%Farbe und Form:Appearance White Or Pale Yellow Amorphous PowderMolekulargewicht:639.82Moxidectin
CAS:Formel:C37H53NO8Reinheit:≥ 95.0%Farbe und Form:White to off-white or yellow powderMolekulargewicht:639.82PharmaVetResiMix 1 Avermectins-v6 10 µg/mL in Methanol
CAS:Kontrolliertes ProduktFarbe und Form:MixtureMoxidectin 100 µg/mL in Acetonitrile
CAS:Formel:C37H53NO8Farbe und Form:Single SolutionMolekulargewicht:639.82Smart Solutions™ v59 PharmaVetResiMix Kit 1
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Farbe und Form:MixtureLC PestiMix 2 10 µg/mL in Acetonitrile
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Farbe und Form:MixtureMoxidectin
CAS:<p>Applications Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);<br></p>Formel:C37H53NO8Farbe und Form:White To Off-WhiteMolekulargewicht:639.82Moxidectin-d3
CAS:Kontrolliertes Produkt<p>Stability Light Sensitive<br>Applications Moxidectin-d3 is a the labelled form of Moxidectin (M744800). Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005)<br></p>Formel:C37H50D3NO8Farbe und Form:White SolidMolekulargewicht:642.84Moxidectin EP H
CAS:Kontrolliertes Produkt<p>Applications Moxidectin EP H is an impurity of Moxidectin which is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);<br></p>Formel:C37H51NO7Farbe und Form:NeatMolekulargewicht:621.8Moxidectin
CAS:<p>Moxidectin is a milbemycin derivative that belongs to the class of macrocyclic lactones. It is used in veterinary medicine to treat infections caused by Diptera larvae, such as the sheep blowfly, Lucilia sericata. Moxidectin has been shown to be an effective drug against c. glabrata, which is resistant to ivermectin and other drugs. Moxidectin binds to P-glycoprotein substrate site 1 and prevents drug efflux from cells by competing with other substrates for binding sites on the transporter. This inhibition of drug efflux may be due to its ability to block P-glycoprotein function or act as a direct inhibitor of ATPase activity. The analytical method used in this study was high performance liquid chromatography (HPLC).</p>Formel:C37H53NO8Reinheit:Min. 92 Area-%Farbe und Form:White PowderMolekulargewicht:639.82 g/molMoxidectin - Bio-X ™
CAS:<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formel:C37H53NO8Reinheit:Min. 95%Farbe und Form:PowderMolekulargewicht:639.82 g/mol
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