CAS 1189987-23-2

Formel: C12H9F3N2O2

InChl: InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)/i2D,3D,4D,5D

InChI Key: VHOGYURTWQBHIL-QFFDRWTDSA-N

SMILES: [2H]C1=C(C(=C(C(=C1C(F)(F)F)[2H])[2H])NC(=O)C2=C(ON=C2)C)[2H]

Leflunomide-d4

CAS: 1189987-23-2

Formel: C₁₂H₅D₄F₃N₂O₂

Farbe und Form: White To Off-White Solid

Molekulargewicht: 274.24

Ref: 4Z-L-042

Leflunomide-d4 (phenyl-d4)

CAS: 1189987-23-2, 75706-12-6

Reinheit: 98 atom % D

Farbe und Form: White Solid

Molekulargewicht: 274.23

Ref: 3U-D6341

Leflunomide-d4

Kontrolliertes Produkt

CAS: 1189987-23-2

Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),

Formel: C₁₂D₄H₅F₃N₂O₂

Farbe und Form: Neat

Molekulargewicht: 274.232

Ref: TR-L322752

Leflunomide-[d4] (phenyl-d4)

CAS: 1189987-23-2

Formel: C₁₂H₉F₃N₂O₂

Molekulargewicht: 274.23

Ref: BE-MD-7888

Leflunomide-d4

CAS: 1189987-23-2

Formel: C₁₂H₉F₃N₂O₂

Molekulargewicht: 274.23

Ref: BE-RMCL047011

Leflunomide-D4

CAS: 1189987-23-2

Leflunomide-D4 is a deuterated compound of Leflunomide. Leflunomide (T1159) has a CAS number of 75706-12-6. Leflunomide (T1159) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.

Formel: C₁₂H₅D₄F₃N₂O₂

Molekulargewicht: 274.23

Ref: TM-TMID-0237

Leflunomide-d4

Kontrolliertes Produkt

CAS: 1189987-23-2

Leflunomide-d4 is a potent inhibitor of protein interactions, which has been used as a research tool to study the effects of peptides on ion channels. Leflunomide-d4 binds to peptides and interacts with them in vitro. This inhibition can be reversed by adding a specific ligand that competes with the binding site. Leflunomide-d4 is also an activator of the receptor for angiotensin II, which is involved in the regulation of blood pressure. It has been shown to inhibit the activation of some ion channels, such as those for potassium and calcium ions, although it does not inhibit other ion channels such as those for sodium and chloride ions. The molecular weight of leflunomide-d4 is 806 daltons and its CAS number is 1189987-23-2.

Formel: C₁₂H₉F₃N₂O₂

Reinheit: Min. 95%

Molekulargewicht: 274.23 g/mol

Ref: 3D-PXB98723