CAS 1235403-62-9

Benzenesulfonamide, 4-[2-(3-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-

CAS: 1235403-62-9

Formel: C₁₈H₁₂Cl₂FN₅O₃S₂

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 500.3540

Ref: IN-DA000KRK

PF 05089771

CAS: 1235403-62-9

PF 05089771

Formel: C₁₈H₁₂Cl₂FN₅O₃S₂

Reinheit: ≥98%, 10 mM in DMSO

Molekulargewicht: 500.35

Ref: 54-BUP02459

PF-05089771

CAS: 1235403-62-9

PF-05089771

Formel: C₁₈H₁₂Cl₂FN₅O₃S₂

Reinheit: 98%

Molekulargewicht: 500.35398

Ref: 54-BISN0013

PF 05089771

CAS: 1235403-62-9

PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.

Formel: C₁₈H₁₂Cl₂FN₅O₃S₂

Reinheit: 99.03% - 99.42%

Farbe und Form: Yellow Solid

Molekulargewicht: 500.35

Ref: TM-T7502L

PF 05089771

CAS: 1235403-62-9

4-(2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy)-5-chloro-2-fluoro-N-(thiazol-4-yl)benzenesulfonamide

Formel: C₁₈H₁₂Cl₂FN₅O₃S₂

Reinheit: 98%

Molekulargewicht: 500.35

Ref: IN-DG292811

PF-05089771

CAS: 1235403-62-9

PF-05089771 is a small molecule that binds to the human P2X7 receptor and blocks its activation by ATP. It has shown to have anti-cancer effects in preclinical studies, and is currently being evaluated in phase 1 clinical trials for various cancers. PF-05089771 has also been shown to have anti-inflammatory properties, as well as pain relief effects in an animal model of chronic pain. This drug is also expressed at high levels in cancer tissues, which may be due to its role in cell proliferation. The structural biology of PF-05089771 is not yet known.

Formel: C₁₈H₁₂Cl₂FN₅O₃S₂

Reinheit: Min. 95%

Molekulargewicht: 500.35 g/mol

Ref: 3D-KZB40362