CAS 124-94-7
:Triamcinolon
Beschreibung:
Triamcinolon ist ein synthetisches Kortikosteroid mit entzündungshemmenden und immunsuppressiven Eigenschaften, das häufig zur Behandlung verschiedener Erkrankungen wie Allergien, Asthma und Autoimmunerkrankungen eingesetzt wird. Es zeichnet sich durch seine Fähigkeit aus, die Freisetzung von Entzündungsmediatoren zu hemmen und Immunantworten zu modulieren. Die chemische Struktur von Triamcinolon umfasst ein Steroidgerüst, das zu seiner biologischen Aktivität und Pharmakokinetik beiträgt. Es wird typischerweise über topische, orale oder injizierbare Wege verabreicht, abhängig von der zu behandelnden Erkrankung. Triamcinolon ist bekannt für seine relativ hohe Potenz im Vergleich zu anderen Kortikosteroiden und kann in verschiedenen Formen formuliert werden, einschließlich Cremes, Salben und injizierbaren Suspensionen. Seine Anwendung kann mit Nebenwirkungen verbunden sein, insbesondere bei langfristiger Anwendung, wie Nebennierenunterdrückung, Gewichtszunahme und erhöhtem Infektionsrisiko. Wie bei jedem Medikament ist es wichtig, Triamcinolon unter ärztlicher Aufsicht zu verwenden, um potenzielle Risiken und Vorteile effektiv zu managen.
Formel:C21H27FO6
InChl:InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
InChI Key:InChIKey=GFNANZIMVAIWHM-OBYCQNJPSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](O)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyme:- (11Beta,16Alpha)-9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-Δ1,4-pregnadiene-3,20-dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-Δ<sup>1,4</sup>-pregnadiene-3,20-dione
- 9-Alpha-Fluoro-11-Beta,16-Alpha,17-Alpha,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 9-Alpha-Fluoro-16-Alpha-Hydroxyprednisolone
- 9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-16α-hydroxyprednisolone
- Acetonide
- Adcortyl
- Aristocort
- Cinolone
- Cl 19823
- Delphicort
- Fluoxiprednisolone
- Fluoxyprednisolone
- Kenacort
- Kenacort AG
- Ledercort
- Mycolog
- Nsc 13397
- Omicilon
- Polcortolon
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11β,16α)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-
- Rodinolone
- Triamcinlon
- Triamcinolon
- Triamcinolone Base
- Triancinolona
- Tricortale
- Weitere Synonyme anzeigen
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Triamcinolone
CAS:Formel:C21H27FO6Reinheit:>98.0%(HPLC)Farbe und Form:White to Almost white powder to crystalMolekulargewicht:394.44Triamcinolone
CAS:TriamcinoloneFormel:C21H27FO6Reinheit:99.5%Farbe und Form:White SolidMolekulargewicht:394.17917Triamcinolone
CAS:Halogenated derivatives of adrenal cortical hormonesFormel:C21H27FO6Farbe und Form:White Off-White PowderMolekulargewicht:394.17917Triamcinolone
CAS:Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formel:C21H27FO6Reinheit:98.66% - 99.60%Farbe und Form:White SolidMolekulargewicht:394.4311β,16α,17α,21-Tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
CAS:Formel:C21H27FO6Reinheit:98%Farbe und Form:SolidMolekulargewicht:394.4339Ref: IN-DA0080N5
100mg37,00€250mg52,00€500mg62,00€1g68,00€2.5g123,00€5g163,00€10g209,00€25g345,00€50g517,00€Triamcinolone
CAS:Formel:C21H27FO6Reinheit:97.5 - 102.5 %Farbe und Form:White to off-white crystalline powderMolekulargewicht:394.43Triamcinolone
CAS:Kontrolliertes ProduktFormel:C21H27FO6Farbe und Form:White To Light YellowMolekulargewicht:394.43Triamcinolone (Standard)
CAS:Triamcinolone (Standard) is the standard substance of Triamcinolone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to translocation of the ligand-receptor complex to the nucleus and induces expression of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both mediators of inflammation. In addition, pro-inflammatory cytokine production, including interleukin (IL)-1and IL-6, and the activation of cytotoxic T-lymphocytes is also inhibited. T-cells are prevented from making IL-2 and proliferating. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis through increasing Ikappa-B expression and curtailing activation of nuclear factor (NF)kappa-B.Formel:C21H27FO6Farbe und Form:SolidMolekulargewicht:394.43Triamcinolone
CAS:Kontrolliertes ProduktFormel:C21H27FO6Farbe und Form:White To Light YellowMolekulargewicht:394.43GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Farbe und Form:ColourlessTriamcinolone
CAS:Kontrolliertes ProduktTriamcinolone is a synthetic corticosteroid that reduces inflammation, suppresses the immune system, and relieves pain. It inhibits the production of cytokines and other inflammatory mediators by binding to specific receptors located in the cells of the immune system. Triamcinolone acetonide is an ester prodrug that is converted to triamcinolone in vivo. This drug has a long-term efficacy because it can be released slowly over time after intravitreal injection. The pharmacokinetic properties of triamcinolone are determined by its lipophilicity and water solubility. Triamcinolone acetonide has been shown to reduce inflammation in chronic arthritis, as well as reducing symptoms of eye disorders such as uveitis or glaucoma. This drug also prevents tumor growth by inhibiting protein synthesis and gene expression at the level of transcription, which leads to decreased cell proliferation or apoptosis.Formel:C21H27FO6Reinheit:Min. 97 Area-%Farbe und Form:White PowderMolekulargewicht:394.43 g/mol
