CAS 1276121-88-0

Formel: C21H18N4OS

InChl: InChI=1S/C21H18N4OS/c1-11-3-4-13(10-22-11)15-6-5-14-16(25-15)7-8-17-18(14)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1

InChI Key: CMWRPDHVGMHLSZ-GFCCVEGCSA-N

SMILES: C[C@@H]1CNC2=C(C(=O)N1)SC3=C2C4=C(C=C3)N=C(C=C4)C5=CN=C(C=C5)C

PF-3644022

CAS: 1276121-88-0

PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.

Formel: C₂₁H₁₈N₄OS

Reinheit: 98.13%

Farbe und Form: Solid

Molekulargewicht: 374.46

Ref: TM-T16501

PF-3644022

CAS: 1276121-88-0

PF-3644022

Formel: C₂₁H₁₈N₄OS

Reinheit: ≥98%

Molekulargewicht: 374.46

Ref: 54-BUP09574

Pf-3644022

CAS: 1276121-88-0

Pf-3644022

Formel: C₂₁H₁₈N₄OS

Reinheit: 99%

Molekulargewicht: 374.45881

Ref: 54-BISN0304

MK2 INHIBITOR

CAS: 1276121-88-0

Formel: C₂₁H₁₈N₄OS

Reinheit: 98.0%

Molekulargewicht: 374.46

Ref: 10-F468418

PF-3644022

CAS: 1276121-88-0

(R)-10-Methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one

Formel: C₂₁H₁₈N₄OS

Reinheit: 99%

Molekulargewicht: 374.46

Ref: IN-DG305536

PF 3644022

CAS: 1276121-88-0

PF 3644022 is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin E2 and other inflammatory mediators. PF 3644022 has shown potent antitumor activity against prostate cancer cells in vitro studies. It is also active against cells that express growth factor receptor, such as thp-1 cells, which may be due to its ability to inhibit the proliferation of these cells. PF 3644022 has been shown to inhibit chronic kidney disease in vivo and can be used for the treatment of bowel diseases, including inflammatory bowel disease and leukemia inhibitory factor. PF 3644022 also inhibits tumor growth in vivo by inhibiting toll-like receptor 4 (TLR4) signaling pathways.

Formel: C₂₁H₁₈N₄OS

Reinheit: Min. 95%

Molekulargewicht: 374.46 g/mol

Ref: 3D-BBC12188

8H-[1,4]Diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, 9,10,11,12-tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-, (10R)-

CAS: 1276121-88-0

Formel: C₂₁H₁₈N₄OS

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 374.4588

Ref: IN-DA000X7V