
CAS 1310347-50-2
:Formel:C18H14F3N5O2
InChl:InChI=1S/C18H14F3N5O2/c1-17(18(20,21)9-28-16(23)26-17)12-6-11(3-4-13(12)19)25-15(27)14-5-2-10(7-22)8-24-14/h2-6,8H,9H2,1H3,(H2,23,26)(H,25,27)/t17-/m1/s1
InChI Key:DVMUZHLUMHPCGZ-QGZVFWFLSA-N
SMILES:C[C@]1(C(COC(=N1)N)(F)F)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)C#N)F
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BACE1-IN-1
CAS:BACE1-IN-1 is a peptide that has been shown to inhibit the activity of BACE1, a protein that is involved in the production of amyloid beta. Amyloid beta is a peptide involved in the formation of plaques in the brain that are responsible for Alzheimer's disease. BACE1-IN-1 blocks amyloid beta production by binding to BACE1 and preventing it from cleaving amyloid precursor protein (APP) into amyloid beta.
Formel:C18H14F3N5O2Reinheit:Min. 95%Molekulargewicht:389.3 g/molBACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Formel:C18H14F3N5O2Reinheit:98%Farbe und Form:SolidMolekulargewicht:389.3313




