CAS 1413431-07-8

Formel: C24H28N2O3

InChl: InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)/i4D3,5D3,6D3

InChI Key: PURKAOJPTOLRMP-ASMGOKTBSA-N

SMILES: [2H]C([2H])([2H])C(C1=C(C=C(C(=C1)C(C)(C)C)NC(=O)C2=CNC3=CC=CC=C3C2=O)O)(C([2H])([2H])[2H])C([2H])([2H])[2H]

N-(2-(tert-Butyl)-5-hydroxy-4-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

CAS: 1413431-07-8

N-(2-(tert-Butyl)-5-hydroxy-4-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

Formel: C₂₄H₁₉D₉N₂O₃

Reinheit: 99.83%

Molekulargewicht: 401.55

Ref: 54-DE2781

Ivacaftor-D9

CAS: 1413431-07-8

Ivacaftor-D9

Formel: C₂₄H₁₉D₉N₂O₃

Reinheit: ≥98%

Molekulargewicht: 401.55

Ref: 54-DE3567

Ivacaftor (4-tertbutyl-d9) (Major)

Kontrolliertes Produkt

CAS: 1413431-07-8

Formel: C₂₄H₁₉D₉N₂O₃

Farbe und Form: Neat

Molekulargewicht: 401.55

Ref: TR-I940603

Ivacaftor-d9

CAS: 1413431-07-8

Formel: C₂₄H₁₉D₉N₂O₃

Molekulargewicht: 401.55

Ref: 4Z-I-056038

Ivacaftor (4-tertbutyl-d9) (major)

CAS: 1413431-07-8

Ivacaftor is a drug substance with the molecular formula C17H20Cl2O3, a monocarboxylic acid amide. Ivacaftor is indicated as a treatment for cystic fibrosis (CF) in patients age 12 years and older who have one of the following mutations: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or R117C. Ivacaftor binds to and activates the CFTR protein by increasing its stability and function. The carboxyl terminal domain of CFTR is required for interaction with ivacaftor. Ivacaftor also potentiates the activity of chromenes such as ivacaftor (4-tertbutyl-d9) and other cftr potentiators such as VX-770. These compounds are being studied in cancer treatment because they may be able to

Formel: C₂₄H₂₈N₂O₃

Reinheit: Min. 95%

Molekulargewicht: 401.5 g/mol

Ref: 3D-NGC43107

Ivacaftor-D9

CAS: 1413431-07-8

Ivacaftor-D9 is a deuterated compound of ivacaftor used for isotope tracing. Ivacaftor is an effective, orally administered CFTR modulator, cystic fibrosis.

Formel: C₂₄H₁₉D₉N₂O₃

Reinheit: 99.13%

Farbe und Form: White Solid

Molekulargewicht: 401.55

Ref: TM-T27098