CAS 1415637-72-7

Formel: C20H18F3N7

InChl: InChI=1S/C20H18F3N7/c1-28-17(12-4-6-13(7-5-12)20(21,22)23)14(10-26-28)16-15-18(29(2)27-16)24-11-25-19(15)30-8-3-9-30/h4-7,10-11H,3,8-9H2,1-2H3

InChI Key: SHAVEYUXRBIMLA-UHFFFAOYSA-N

SMILES: CN1C(=C(C=N1)C2=NN(C3=C2C(=NC=N3)N4CCC4)C)C5=CC=C(C=C5)C(F)(F)F

4-(1-Azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS: 1415637-72-7

4-(1-Azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1H-pyrazolo[3,4-d]pyrimidine

Formel: C₂₀H₁₈F₃N₇

Reinheit: ≥98% (HPLC)

Molekulargewicht: 413.4

Ref: 54-PC1030064

PF-05085727

CAS: 1415637-72-7

PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.

Formel: C₂₀H₁₈F₃N₇

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 413.399

Ref: TM-T16482

4-(1-Azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS: 1415637-72-7

Formel: C₂₀H₁₈F₃N₇

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 413.3990

Ref: IN-DA01E6OD

PF 05085727

CAS: 1415637-72-7

Inhibitor of cGMP-dependent phosphodiesterase 2A (PDE2A) with IC50 = 2 nM and has higher affinity over other phosphodiesterases (> 500-fold). Increases cGMP in rodent brain in vivo. Reverses anxiolytic behaviour, enhances performance of new object recognition and social recognition tasks.  Potentiates NMDA signalling and reverses behavioural effects of NMDA antagonists.

Formel: C₂₀H₁₈F₃N₇

Reinheit: Min. 95%

Farbe und Form: White To Off-White Solid

Molekulargewicht: 413.4 g/mol

Ref: 3D-BP165159