CAS 1430213-30-1
:Formel:C15H9F4N5OS
InChl:InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
InChI Key:WMCOYUSJXXCHFH-UHFFFAOYSA-N
SMILES:C1=CC(=C(C=C1NC(=O)NC2=NN=C(S2)C3=CC=NC=C3)C(F)(F)F)F
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1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea
CAS:1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)UreaFormel:C15H9F4N5OSReinheit:98+%Molekulargewicht:383.32ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formel:C15H9F4N5OSReinheit:98.12%Farbe und Form:Yellow SolidMolekulargewicht:383.323ML216
CAS:1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)ureaFormel:C15H9F4N5OSReinheit:98+%Molekulargewicht:383.321-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea
CAS:Reinheit:98+%Molekulargewicht:383.3200073ML-216
CAS:Kontrolliertes ProduktApplications ML-216 is a small molecule inhibitor of Bloom (BLM) helicase.
References Rosenthal, A., et al.: Bioorg. Med. Chem. Lett., 23, 5660 (2013); Nguyen, G., et al.: Chem. Biol., 20, 55(2013)Formel:C15H9F4N5OSFarbe und Form:NeatMolekulargewicht:383.324ML216
CAS:ML216 is a chemotherapeutic drug that inhibits the repair mechanism of prostate cancer cells. It binds to leukocyte antigen (LFA-1) on the surface of tumor cells, and blocks the activity of suppressor genes that regulate the growth and development of these cells. ML216 has been shown to be active against prostate cancer cell lines in vitro and in vivo studies. This drug also has membrane permeability and anticancer activity.Formel:C15H9F4N5OSReinheit:Min. 95%Molekulargewicht:383.32 g/molRef: 3D-FHC21330
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