CAS 14599-46-3
:5-Carboxy-2'-desoxyuridin
Formel:C10H12N2O7
InChl:InChI=1S/C10H12N2O7/c13-3-6-5(14)1-7(19-6)12-2-4(9(16)17)8(15)11-10(12)18/h2,5-7,13-14H,1,3H2,(H,16,17)(H,11,15,18)/t5-,6+,7+/m0/s1
InChI Key:InChIKey=GAGYTXTVUMXAOC-RRKCRQDMSA-N
SMILES:O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(O)=O)C(=O)N1
Synonyme:- 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
- 2'-Deoxy-5-carboxyuridine
- 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- Uridine, 5-Carboxy-2'-Deoxy-
- 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
- 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- 5-Carboxy-2'-deoxyuridine
- 5-Carboxy-2′-deoxyuridine
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Trifluridine Related Compound A
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormel:C10H12N2O7Farbe und Form:White Off-White PowderMolekulargewicht:272.06445Trifluridine Related Compound A
CAS:Formel:C10H12N2O7Farbe und Form:Pale Yellow SolidMolekulargewicht:272.211-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
CAS:Formel:C10H12N2O7Reinheit:95%Farbe und Form:SolidMolekulargewicht:272.21155-Carboxy-2'-deoxyuridine
CAS:5-Carboxy-2'-deoxyuridine is a nucleoside analogue that inhibits herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) replication. It is used to treat genital herpes infections caused by HSV-1 or HSV-2. 5-Carboxy-2'-deoxyuridine has been shown to inhibit the growth of human cancer cells in culture, and is currently being investigated as a potential anticancer drug. This drug binds with high affinity to the viral DNA polymerase, forming a covalent bond with the uracil base in the viral DNA chain. This prevents further elongation of the chain, inhibiting viral replication. 5-Carboxy-2'-deoxyuridine also inhibits cellular protein synthesis and cell division, which may be due to its ability to bind with aldehyde groups on surfactant proteins.END>Formel:C10H12N2O7Reinheit:Min. 95%Farbe und Form:PowderMolekulargewicht:272.21 g/mol5-Carboxy-2'-deoxyuridine
CAS:Kontrolliertes ProduktApplications 5-Carboxy-2'-deoxyuridine, is a derivative of Trifluridine, an anti-herpesvirus antiviral drug, used primarily on the eye.
References Kuster, P., et al.: CLAO J. 24(2), 122 (1998); O’Brien, W., Invest. Opthalmol. Vis. Sci., 32 (9), 2455 (1991);Formel:C10H12N2O7Farbe und Form:NeatMolekulargewicht:272.21








