CAS 14937-32-7
:Penta-O-galloyl-β-D-Glucose
Beschreibung:
Penta-O-galloyl-β-D-Glucose ist eine polyphenolische Verbindung, die aus Glukose abgeleitet ist und durch das Vorhandensein von fünf galloylierten Gruppen gekennzeichnet ist, die an die Hydroxylgruppen des Glukosemoleküls esterifiziert sind. Diese Verbindung weist starke antioxidative Eigenschaften auf, die auf das Vorhandensein mehrerer phenolischer Hydroxylgruppen zurückzuführen sind, die freie Radikale abfangen können. Penta-O-galloyl-β-D-Glucose ist bekannt für seine potenziellen gesundheitlichen Vorteile, einschließlich entzündungshemmender, antimikrobieller und krebsbekämpfender Aktivitäten, was es zu einem interessanten Thema in der pharmazeutischen und nutraceutical Forschung macht. Seine Löslichkeit ist im Allgemeinen in organischen Lösungsmitteln höher als in Wasser, was seine Bioverfügbarkeit und Anwendung in verschiedenen Formulierungen beeinflussen kann. Die Stabilität der Verbindung kann durch Faktoren wie pH und Temperatur beeinflusst werden, die wichtige Überlegungen für die Lagerung und Verwendung sind. Darüber hinaus trägt die strukturelle Komplexität zu seinen einzigartigen Wechselwirkungen mit biologischen Systemen bei, was sein Potenzial als therapeutisches Mittel weiter erhöht. Insgesamt stellt Penta-O-galloyl-β-D-Glucose ein bedeutendes Forschungsfeld im Bereich der Naturprodukte und der medizinischen Chemie dar.
Formel:C41H32O26
InChl:InChI=1S/C41H32O26/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16/h1-10,27,33-35,41-56H,11H2/t27-,33-,34+,35-,41+/m1/s1
InChI Key:InChIKey=QJYNZEYHSMRWBK-NIKIMHBISA-N
SMILES:O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC(=O)C4=CC(O)=C(O)C(O)=C4)O[C@H](COC(=O)C5=CC(O)=C(O)C(O)=C5)[C@H]2OC(=O)C6=CC(O)=C(O)C(O)=C6
Synonyme:- 1,2,3,4,6-O-Pentagalloylglucose
- 1,2,3,4,6-Penta-O-Galloyl-B-D-Glucopyranose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucoside
- 1,2,3,4,6-Penta-O-galloyl-β-glucopyranose
- 1,2,3,4,6-Penta-O-galloylglucose
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucose
- 1,2,3,4,6-Pentagalloylglucose
- 1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose
- Db 03208
- G 7548
- Gallic acid, pentaester with β-<span class="text-smallcaps">D</span>-glucopyranose
- Gallotannin 15
- Glucopyranose, pentagallate, β-<span class="text-smallcaps">D</span>-
- PGG
- Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose
- Penta-O-galloylglucose
- Penta-Ortho-Galloylglucose
- Pentagalloyl Glucose
- Pentagalloyl-<span class="text-smallcaps">D</span>-glucose
- Pentagalloylglucose
- beta-penta-O-galloyl-glucose
- β-1,2,3,4,6-Pentagalloylglucose
- β-<span class="text-smallcaps">D</span>-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
- β-<span class="text-smallcaps">D</span>-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
- Glucopyranose, pentagallate, β-D-
- β-D-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
- 1,2,3,4,6-Pentagalloyl-β-D-glucose
- β-D-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
- Weitere Synonyme anzeigen
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(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetrakis(3,4,5-Trihydroxybenzoate)
CAS:(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetrakis(3,4,5-Trihydroxybenzoate)Formel:C41H32O26Reinheit:98%Molekulargewicht:940.68Pentagalloylglucose
CAS:PentagalloylglucoseFormel:C41H32O26Reinheit:≥98%Farbe und Form:SolidMolekulargewicht:940.681,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose
CAS:Formel:C41H32O26Reinheit:(HPLC) ≥ 98.0%Farbe und Form:White to yellow or light brown powderMolekulargewicht:940.68β-D-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
CAS:Formel:C41H32O26Reinheit:98%Farbe und Form:SolidMolekulargewicht:940.6772Pentagalloylglucose (Standard)
CAS:Pentagalloylglucose (Standard) is a reference standard for research and analysis in studies involving Pentagalloylglucose. 1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses potent anti-proliferative and anti-invasive effects, it also has inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity. 3. PGG may serve as a model for the development of new types of anti-diabetic and anti-metabolic syndrome therapeutics. 4. 1, 2, 3, 4, 6-Penta- O -galloyl-β- d -glucose has vasodilatory and anti-inflammatory effects, it dilates vascular smooth muscle and suppresses the vascular inflammatory process via endothelium-dependent nitric oxide (NO)/cGMP signaling. 5. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose can decrease the level of extracellular hepatitis B virus (HBV) (IC5, 1. microg/ml) in a dose-dependent manner, it also can reduce the HBsAg level by 25% at a concentration of 4 microg/ml; the gallate structure of PGG may play a critical role in the inhibition of anti-HBV activity, suggests that PGG could be a candidate for developing an anti-HBV agent. 6. 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose has anti-parasitic activity, displays an EC5 value of 67 μM, at least 6.6-fold more effective than the standard drug benznidazole against trypomastigote forms of T. cruzi.Formel:C41H32O26Molekulargewicht:940.67721,2,3,4,6-Penta-O-galloyl-b-D-glucopyranose (>85%)
CAS:Kontrolliertes ProduktStability Hygroscopic, Temperature Sensitive
Applications Found to exhibit in vitro growth-inhibiting effect on human hepatocellular carcinoma cell line, SK-HEP-1 cells.
References Oh, G-S, et al.: Cancer Letters, 174, 17 ( 2001)Formel:C41H32O26Reinheit:>85%Farbe und Form:NeatMolekulargewicht:940.681,2,3,4,6-O-pentagalloylglucose
CAS:(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4,5-trihydroxybenzoate)Formel:C41H32O26Reinheit:98%Molekulargewicht:940.68Pentagalloylglucose
CAS:1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities.Formel:C41H32O26Reinheit:99.17% - 99.97%Farbe und Form:Gray SolidMolekulargewicht:940.67721,2,3,4,6-Pentagalloyl β-D-glucose
CAS:Natural glycosideFormel:C41H32O26Reinheit:≥ 90.0 % (HPLC)Farbe und Form:PowderMolekulargewicht:940.691,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose
CAS:A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.Formel:C41H32O26Reinheit:Min. 96 Area-%Farbe und Form:PowderMolekulargewicht:940.68 g/molPentagalloylglucose - Bio-X ™
CAS:A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.Formel:C41H32O26Reinheit:Min. 98 Area-%Farbe und Form:PowderMolekulargewicht:940.68 g/mol
