CAS 1628256-23-4

Formel: C26H34N8O

InChl: InChI=1S/C26H34N8O/c1-18(2)32-10-12-33(13-11-32)20-6-7-22(27-16-20)30-25-28-15-19-14-21-24(35)29-17-26(8-4-3-5-9-26)34(21)23(19)31-25/h6-7,14-16,18H,3-5,8-13,17H2,1-2H3,(H,29,35)(H,27,28,30,31)

InChI Key: YPJRHEKCFKOVRT-UHFFFAOYSA-N

SMILES: CC(C)N1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6

Lerociclib

CAS: 1628256-23-4

Lerociclib

Formel: C₂₆H₃₄N₈O

Reinheit: ≥98%

Molekulargewicht: 474.6

Ref: 54-BUP01744

Lerociclib

CAS: 1628256-23-4

2'-((5-(4-Isopropylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one

Formel: C₂₆H₃₄N₈O

Reinheit: 99%

Molekulargewicht: 474.6

Ref: IN-DG766449

Lerociclib (G1T38)

CAS: 1628256-23-4

Lerociclib (G1T38) is a potent inhibitor of breast cancer cells with structural similarity to palbociclib. It is an inhibitor of the CDK4/6 complex that is responsible for cell cycle progression at G1 phase, as well as the retinoblastoma (RB) protein. The drug has been shown to inhibit tumor growth and induce apoptosis in xenograft tumor models. Lerociclib also inhibits the growth of cervical cancer cells in vitro and reduces tumor weight in a mouse model by inhibiting proliferation and inducing apoptosis.

Formel: C₂₆H₃₄N₈O

Reinheit: Min. 95%

Molekulargewicht: 474.61 g/mol

Ref: 3D-DQC25623

Lerociclib

CAS: 1628256-23-4

Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.

Formel: C₂₆H₃₄N₈O

Reinheit: 99.56%

Farbe und Form: Solid

Molekulargewicht: 474.6

Ref: TM-T11345