CAS 163768-50-1

Formel: C40H67N5O8

InChl: InChI=1S/C40H67N5O8/c1-13-26(6)35(44(10)39(49)33(24(2)3)42-38(48)34(25(4)5)43(8)9)31(52-11)23-32(46)45-21-17-20-30(45)36(53-12)27(7)37(47)41-29(40(50)51)22-28-18-15-14-16-19-28/h14-16,18-19,24-27,29-31,33-36H,13,17,20-23H2,1-12H3,(H,41,47)(H,42,48)(H,50,51)/t26-,27+,29-,30-,31+,33-,34-,35-,36+/m0/s1

InChI Key: LGNCNVVZCUVPOT-FUVGGWJZSA-N

SMILES: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C

Auristatin F

CAS: 163768-50-1

Auristatin F

Formel: C₄₀H₆₇N₅O₈

Reinheit: 99%

Molekulargewicht: 745.99

Ref: 54-OR1024019

Auristatin F

CAS: 163768-50-1

Auristatin F

Formel: C₄₀H₆₇N₅O₈

Reinheit: 99%

Molekulargewicht: 745.99

Ref: 54-BUP11580

Auristatin F-d8

CAS: 163768-50-1

Formel: C₄₀H₅₉D₈N₅O₈

Molekulargewicht: 754.05

Ref: 4Z-PA-329005

Auristatin F

CAS: 163768-50-1

Formel: C₄₀H₆₇N₅O₈

Molekulargewicht: 746.00

Ref: 4Z-PA-329004

Auristatin F

CAS: 163768-50-1

Formel: C₄₀H₆₇N₅O₈

Molekulargewicht: 746.0

Ref: BE-RMCP470004

Auristatin F

CAS: 163768-50-1

(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid

Formel: C₄₀H₆₇N₅O₈

Reinheit: 99%

Molekulargewicht: 745.99

Ref: IN-DG630408

Auristatin F TFA Salt

Kontrolliertes Produkt

CAS: 163768-50-1

Stability Hygroscopic
Applications Auristatin F is an antimitotic auristatin derivative that has been shown as a potent antitumor agent.
References Doronina S.O., et al.: Bioconjugate Chem., 17, 114-124 (2006);

Formel: C₄₀H₆₇N₅O₈•x(C₂HF₃O₂)

Farbe und Form: Neat

Molekulargewicht: 745.9911402

Ref: TR-A794100

Auristatin F

CAS: 163768-50-1

Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.

Formel: C₄₀H₆₇N₅O₈

Reinheit: 98.41% - 99.25%

Farbe und Form: White Solid

Molekulargewicht: 745.9887

Ref: TM-T14349

Auristatin F TFA Salt

CAS: 163768-50-1

Auristatin F TFA salt is a potent antitumor agent that can be used for the treatment of solid tumours. It inhibits the growth of cancer cells by binding to epidermal growth factor (EGF) receptors and blocking the action of EGF. Auristatin F TFA salt has been shown to induce apoptosis in prostate cancer cells and can also act as a potential biomarker for tumour response. The drug is not toxic to healthy cells, but it is rapidly eliminated from the body due to its short half-life. Auristatin F TFA salt has been shown to have pharmacokinetic properties that are similar in mice, rats, and humans. This drug also binds monoclonal antibodies against EGFR, which may serve as an alternative treatment for cancer patients who develop resistance to temozolomide.

Formel: C₄₀H₆₇N₅O₈•(C₂HF₃O₂)x

Reinheit: Min. 95%

Molekulargewicht: 745.99 g/mol

Ref: 3D-NGA76850

N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine

CAS: 163768-50-1

Formel: C₄₀H₆₇N₅O₈

Reinheit: 99%

Farbe und Form: Solid

Molekulargewicht: 745.9887

Ref: IN-DA00ABIO