CAS 1638250-96-0

Formel: C19H17N7O3

InChl: InChI=1S/C19H17N7O3/c1-24-17-16(18(28)25(2)19(24)29)26(11-20-17)10-15(27)21-14-9-8-13(22-23-14)12-6-4-3-5-7-12/h3-9,11H,10H2,1-2H3,(H,21,23,27)

InChI Key: QTRXIFVSTWXRJJ-UHFFFAOYSA-N

SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NC3=NN=C(C=C3)C4=CC=CC=C4

ETC-159

CAS: 1638250-96-0

ETC-159

Formel: C₁₉H₁₇N₇O₃

Reinheit: ≥95%

Molekulargewicht: 391.38

Ref: 54-BUP06111

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-N-(6-Phenylpyridazin-3-Yl)Acetamide

CAS: 1638250-96-0

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-N-(6-Phenylpyridazin-3-Yl)Acetamide

Formel: C₁₉H₁₇N₇O₃

Reinheit: 98%

Molekulargewicht: 391.38

Ref: 54-OR1023188

ETC-159

CAS: 1638250-96-0

ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.

Formel: C₁₉H₁₇N₇O₃

Reinheit: 96.87% - 99.30%

Farbe und Form: Solid

Molekulargewicht: 391.3834

Ref: TM-T4043

ETC-159

CAS: 1638250-96-0

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(6-phenylpyridazin-3-yl)acetamide

Formel: C₁₉H₁₇N₇O₃

Reinheit: 98%

Molekulargewicht: 391.38

Ref: IN-DG630410

7H-PURINE-7-ACETAMIDE, 1,2,3,6-TETRAHYDRO-1,3-DIMETHYL-2,6-DIOXO-N-(6-PHENYL-3-PYRIDAZINYL)-

CAS: 1638250-96-0

Reinheit: 98%

Molekulargewicht: 391.3909912

Ref: 10-F801801

1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide

Kontrolliertes Produkt

CAS: 1638250-96-0

Applications 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide is a novel potent PORCN inhibitor that blocks the secretion and activity of all Wnts.
References Madan, B., et al.: Oncogene, 35, 2197-2207 (2016);

Formel: C₁₉H₁₇N₇O₃

Farbe und Form: Neat

Molekulargewicht: 391.383

Ref: TR-T293433

7H-PURINE-7-ACETAMIDE, 1,2,3,6-TETRAHYDRO-1,3-DIMETHYL-2,6-DIOXO-N-(6-PHENYL-3-PYRIDAZINYL)-

CAS: 1638250-96-0

Formel: C₁₉H₁₇N₇O₃

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 391.3834

Ref: IN-DA001UF2

ETC-159

Kontrolliertes Produkt

CAS: 1638250-96-0

ETC-159 is a monoclonal antibody that binds to and inhibits the function of β-catenin. It is an orally administered drug that has been shown to be effective for the treatment of solid tumours, such as colorectal cancer. ETC-159 blocks the cell signaling pathways mediated by β-catenin, which may lead to tumor suppression. This drug also has the ability to inhibit TNF-α and suppressor genes in cancer cells, which are involved in tumor growth. The chemical structure of this molecule includes a pan-PI3K inhibitor with a potential application in inhibiting cancers that are not responsive to conventional therapy.

Formel: C₁₉H₁₇N₇O₃

Reinheit: Min. 95%

Molekulargewicht: 391.38 g/mol

Ref: 3D-NQC25096