CAS 1654725-02-6

Formel: C16H20N4O3S

InChl: InChI=1S/C16H20N4O3S/c1-15(2)7-8-10(12(17)21)14(24-11(8)16(3,4)23-15)19-13(22)9-5-6-18-20-9/h5-6H,7H2,1-4H3,(H2,17,21)(H,18,20)(H,19,22)

InChI Key: GHTGYZMBQPXTCQ-UHFFFAOYSA-N

SMILES: CC1(CC2=C(C(O1)(C)C)SC(=C2C(=O)N)NC(=O)C3=CC=NN3)C

N-(3-Carbamoyl-5,5,7,7-Tetramethyl-5,7-Dihydro-4H-Thieno[2,3-c]Pyran-2-Yl)-1H-Pyrazole-3-Carboxamide

CAS: 1654725-02-6

N-(3-Carbamoyl-5,5,7,7-Tetramethyl-5,7-Dihydro-4H-Thieno[2,3-c]Pyran-2-Yl)-1H-Pyrazole-3-Carboxamide

Formel: C₁₆H₂₀N₄O₃S

Reinheit: 99%

Molekulargewicht: 348.42

Ref: 54-OR1025801

GLPG1837

CAS: 1654725-02-6

GLPG1837

Formel: C₁₆H₂₀N₄O₃S

Reinheit: 99.5%

Molekulargewicht: 348.42

Ref: 54-BUP15197

GLPG1837

CAS: 1654725-02-6

GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.

Formel: C₁₆H₂₀N₄O₃S

Reinheit: 99.64% - 99.91%

Farbe und Form: Solid

Molekulargewicht: 348.42

Ref: TM-T7083

N-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide

CAS: 1654725-02-6

N-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide

Formel: C₁₆H₂₀N₄O₃S

Reinheit: 99%

Molekulargewicht: 348.42

Ref: IN-DG00782344

N-[3-(Aminocarbonyl)-4,7-dihydro-5,5,7,7-tetramethyl-5H-thieno[2,3-c]pyran-2-yl]-1H-pyrazole-3-carboxamide

CAS: 1654725-02-6

Formel: C₁₆H₂₀N₄O₃S

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 348.4200

Ref: IN-DA01EOIM

GLPG 1837

CAS: 1654725-02-6

GLPG 1837 is a small molecule potentiator, which is derived from a synthetic compound designed to target cystic fibrosis transmembrane conductance regulator (CFTR) protein variants. The source of GLPG 1837 is based on medicinal chemistry approaches focused on optimizing interactions with CFTR. The mode of action involves enhancing the channel gating of the CFTR protein, specifically addressing defects in CFTR function by increasing the probability of the channel being open and facilitating chloride ion transport across cell membranes.

Formel: C₁₆H₂₀N₄O₃S

Reinheit: Min. 95%

Molekulargewicht: 348.42 g/mol

Ref: 3D-ERC72502