CAS 1676893-24-5

Formel: C29H27F2N5O5S2

InChl: InChI=1S/C29H27F2N5O5S2/c1-41-29-27(34-43(39,40)28-8-6-23(30)18-25(28)31)17-22(19-33-29)21-5-7-26-24(16-21)20(9-10-32-26)4-3-11-35-12-14-36(15-13-35)42(2,37)38/h5-10,16-19,34H,11-15H2,1-2H3

InChI Key: BBRINJUWZRLWKK-UHFFFAOYSA-N

SMILES: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C#CCN4CCN(CC4)S(=O)(=O)C)NS(=O)(=O)C5=C(C=C(C=C5)F)F

NSC781406

CAS: 1676893-24-5

NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).

Formel: C₂₉H₂₇F₂N₅O₅S₂

Reinheit: 99.58%

Farbe und Form: Solid

Molekulargewicht: 627.682

Ref: TM-T16355

NSC781406

CAS: 1676893-24-5

NSC781406

Formel: C₂₉H₂₇F₂N₅O₅S₂

Reinheit: ≥98%

Molekulargewicht: 627.68

Ref: 54-BUP09735

NSC 781406

CAS: 1676893-24-5

Formel: C₂₉H₂₇F₂N₅O₅S₂

Reinheit: 99%

Molekulargewicht: 627.6820

Ref: IN-DA01EO9W

NSC781406

CAS: 1676893-24-5

NSC781406 is a drug that has been shown to have anti-tumor effects in animal models of cancer. It is an inhibitor of phosphatases, which are enzymes that remove phosphate groups from phospholipids and proteins. NSC781406 has been shown to inhibit the growth of tumor cells in xenograft models. In addition, it inhibits the proliferation of pancreatic cancer cells in vitro and reduces tumor size in mice with pancreatic cancer. NSC781406 induces cytotoxic effects by modulating the activity of enzymes involved in cellular signaling pathways such as phosphoinositide kinase (PI3K) and protein kinase C (PKC).

Formel: C₂₉H₂₇F₂N₅O₅S₂

Reinheit: Min. 95%

Molekulargewicht: 627.68 g/mol

Ref: 3D-BSC89324