CAS 16941-32-5

Glukagon

Beschreibung:

Glukagon ist ein Peptidhormon, das von den Alpha-Zellen der Bauchspeicheldrüse produziert wird und hauptsächlich am Glukosestoffwechsel beteiligt ist. Es besteht aus 29 Aminosäuren und spielt eine entscheidende Rolle bei der Erhöhung des Blutzuckerspiegels, indem es die Glykogenolyse und die Gluconeogenese in der Leber fördert. Glukagon wird typischerweise als Reaktion auf niedrige Blutzuckerspiegel freigesetzt und wirkt als kontraregulatorisches Hormon zu Insulin. Seine Struktur umfasst eine einzelne Kette von Aminosäuren mit spezifischen funktionellen Gruppen, die seine biologische Aktivität erleichtern. Die CAS-Nummer 16941-32-5 identifiziert Glukagon in chemischen Datenbanken und gewährleistet eine präzise Kommunikation über diese Substanz. In therapeutischen Kontexten wird Glukagon als Medikament zur Behandlung schwerer Hypoglykämie eingesetzt und wird durch Injektion verabreicht. Es wird auch in diagnostischen Verfahren verwendet, wie z.B. in bildgebenden Studien des Magen-Darm-Trakts. Insgesamt ist Glukagon entscheidend für die Aufrechterhaltung der Glukosehomöostase und spielt eine Schlüsselrolle in der Stoffwechselregulation.

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

InChl: InChI=1/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1

Synonyme:

• Glucagon (1-29) (human, bovine, porcine)
• Glucagon, human recombinant
• H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
• L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
• Glucagon Hydrochloride(Human)

Glucagon (1-29) (human, rat, porcine)

CAS: 16941-32-5

Bachem ID: 4088814.

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: 96.4%

Farbe und Form: White Lyophilisate

Molekulargewicht: 3482.8

Ref: 01-4088814

Glucagon (1-29) (human, rat, porcine)

CAS: 16941-32-5

Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: 100.0%

Farbe und Form: White Powder

Molekulargewicht: 3482.8

Ref: 01-4033017

HUMAN GLUCAGON CRS

CAS: 16941-32-5

HUMAN GLUCAGON CRS

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Molekulargewicht: 3482.747

Ref: 41-Y0000191

Glucagon (HUMAN)

CAS: 16941-32-5

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Farbe und Form: White Powder

Molekulargewicht: 3480.6157

Ref: 45-1294036

Glucagon

CAS: 16941-32-5

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: 99%

Farbe und Form: Solid

Molekulargewicht: 3482.7473

Ref: IN-DA0039VM

Glucagon PentaHCl

CAS: 16941-32-5

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S·5HCl

Molekulargewicht: 3482.80 5*36.46

Ref: 4Z-PG-194012

Glucagon

CAS: 16941-32-5

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Molekulargewicht: 3482.80

Ref: 4Z-PG-194007

Glucagon

CAS: 16941-32-5

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: (HPLC) ≥ 95.0%

Farbe und Form: White powder

Molekulargewicht: 3482.75

Ref: 7W-GX2829

Glucagon Hydrochlide

CAS: 16941-32-5

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: 95%~99%

Farbe und Form: White to Off-white Powder

Molekulargewicht: 3482.75

Ref: BP-BPPG036

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: 99.56% - 99.56%

Farbe und Form: Solid

Molekulargewicht: 3482.75

Ref: TM-T15389

Glucagon RS

CAS: 16941-32-5

Farbe und Form: White Solid

Ref: 2K-1048400021

Glucagon tifluoroacetic acid

CAS: 16941-32-5

Please enquire for more information about Glucagon tifluoroacetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S•(CF₃CO₂H)x

Molekulargewicht: 3,482.75 g/mol

Ref: 3D-G-1000

Glucagon (Human)

CAS: 16941-32-5

Glucagon (Human) is a recombinant peptide hormone, which is synthesized to mimic the natural glucagon produced by alpha cells in the pancreas. This biopharmaceutical is derived from a DNA recombinant technology source, offering a high level of purity and consistency. Its mode of action involves binding to glucagon receptors on liver cells, stimulating glycogenolysis and gluconeogenesis. This results in the rapid conversion of glycogen into glucose, thereby raising blood sugar levels.Glucagon (Human) is primarily utilized in the treatment of severe hypoglycemia, especially in diabetic patients unable to consume oral glucose due to unconsciousness or confusion. Its application is critical in acute settings where rapid intervention is necessary to prevent neurological damage from prolonged hypoglycemia. Additionally, the research and clinical use of glucagon extend to investigating its potential in counteracting beta-blocker and calcium channel blocker overdoses, where it acts to increase cardiac output. This hormone's pharmaceutical development has provided a crucial tool in both emergency response and broader therapeutic research contexts.

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: Min. 95%

Molekulargewicht: 3,482.7 g/mol

Ref: 3D-PGL-4098-S

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Glucagon (1-29), bovine, human, porcine, is a peptide hormone, which is derived from bovine, human, and porcine sources. It comprises 29 amino acids and functions as a crucial regulator of glucose metabolism by promoting the increase of blood glucose levels. The mode of action involves binding to receptors on liver cells, activating adenylate cyclase, and subsequently increasing intracellular cyclic AMP. This cascade triggers glycogenolysis and gluconeogenesis, leading to elevated blood glucose.In scientific research, Glucagon (1-29), bovine, human, porcine, is utilized to study metabolic pathways and the regulation of glucose homeostasis. Its applications extend to diabetes research, where it serves as a model for understanding glucagon's role in insulin resistance and pancreatic beta-cell dysfunction. Furthermore, this product is employed in the development of therapeutic strategies for hypoglycemic events experienced by diabetic patients. It also serves as a tool in pharmacological studies to elucidate receptor-ligand interactions and signaling mechanisms in different species.

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Reinheit: Min. 95%

Molekulargewicht: 3,482.78 g/mol

Ref: 3D-PG16975

Glucagon

CAS: 16941-32-5

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Molekulargewicht: 3482.8

Ref: ST-EA-CP-G38025

Glucagon (1-29) trifluoroacetate salt, human

CAS: 16941-32-5

A peptide hormone that plays a role in maintaining glucose homeostasis This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Farbe und Form: White, Lyophilized powder

Ref: 02-J60827

Glucagon Hydrochloride

CAS: 16941-32-5

Please enquire for more information about Glucagon Hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formel: C₁₅₃H₂₂₅N₄₃O₄₉S

Molekulargewicht: 3,482.82 g/mol

Ref: 3D-PP51369