
CAS 1715025-32-3
:Formel:C26H27BrF3N5O2
InChl:InChI=1S/C26H27BrF3N5O2/c1-32-11-21(15-6-16(27)10-17(28)7-15)35-26(37)18-4-2-14(9-19(18)29)24-25(31)33-12-22(34-24)13-3-5-23(36)20(30)8-13/h2,4,6-7,9-10,12-13,20-21,23,32,36H,3,5,8,11H2,1H3,(H2,31,33)(H,35,37)/t13-,20-,21+,23-/m0/s1
InChI Key:YFCIFWOJYYFDQP-PTWZRHHISA-N
SMILES:CNC[C@H](C1=CC(=CC(=C1)Br)F)NC(=O)C2=C(C=C(C=C2)C3=NC(=CN=C3N)[C@H]4CC[C@@H]([C@H](C4)F)O)F
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Rineterkib
CAS:Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.Formel:C26H27BrF3N5O2Reinheit:99.73%Farbe und Form:SolidMolekulargewicht:578.424ERK-IN-1
CAS:ERK-IN-1 is a selective inhibitor of the mitogen-activated protein kinase. It has been shown to inhibit proliferation of cells in culture and may be useful for treating metastatic melanoma and other cancers. ERK-IN-1 inhibits the activity of CDK4/6, which are enzymes that regulate cell division. This inhibition leads to decreased cell proliferation and tumor growth, which is responsible for its antineoplastic activity. ERK-IN-1 also inhibits signal transduction pathways in cells, which may lead to cancer prevention.Formel:C26H27BrF3N5O2Reinheit:Min. 95%Molekulargewicht:578.4 g/molRef: 3D-QTC02532
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