CAS 1800115-22-3

Formel: C25H29ClO6

InChl: InChI=1S/C25H29ClO6/c26-20-6-3-14(25-24(30)23(29)22(28)21(12-27)32-25)8-17(20)7-13-1-4-18(5-2-13)31-19-10-15-9-16(15)11-19/h1-6,8,15-16,19,21-25,27-30H,7,9-12H2/t15-,16+,19?,21-,22-,23+,24-,25+/m1/s1

InChI Key: WDBIPGHUEJEKTC-VWQPKTIXSA-N

SMILES: C1[C@H]2[C@@H]1CC(C2)OC3=CC=C(C=C3)CC4=C(C=CC(=C4)[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)Cl

Janagliflozin

CAS: 1800115-22-3

Janagliflozin is an orally active and highly selective inhibitor of sodium-glucose co-transporter protein 2 (SGLT2) with an IC₅₀ value of 0.0058 μM, and an IC₅₀ of 4.802 μM for SGLT1. It inhibits SGLT2 in the proximal renal tubules, reducing glucose reabsorption and promoting urinary glucose excretion (UGE), thereby lowering blood glucose levels. Janagliflozin holds potential for research in treating type 2 diabetes.

Formel: C₂₅H₂₉ClO₆

Molekulargewicht: 460.95

Ref: TM-T214194