CAS 1802426-00-1

Formel: C30H24Cl2F5N9O4

InChl: InChI=1S/C28H23Cl2F2N9O2.C2HF3O2/c1-15-3-2-4-23(20-9-16(7-8-33-20)26-21(36-27(15)43)12-35-41(26)28(31)32)39-14-34-19(11-25(39)42)18-10-17(29)5-6-22(18)40-13-24(30)37-38-40;3-2(4,5)1(6)7/h5-15,23,28H,2-4H2,1H3,(H,36,43);(H,6,7)/t15-,23+;/m1./s1

InChI Key: BNDDKCJHMXEGIX-WUTOIGTNSA-N

SMILES: C[C@@H]1CCC[C@@H](C2=NC=CC(=C2)C3=C(C=NN3C(F)F)NC1=O)N4C=NC(=CC4=O)C5=C(C=CC(=C5)Cl)N6C=C(N=N6)Cl.C(=O)(C(F)(F)F)O

Milvexian TFA

CAS: 1802426-00-1

Milvexian (BMS-986177/JNJ-70033093) is a factor XIa inhibitor with Ki=44 nM for kallikrein, Ki=35 nM for chymotrypsin, 32% bioavailability.

Formel: C₃₀H₂₆Cl₂F₅N₉O₄

Farbe und Form: Solid

Molekulargewicht: 742.49

Ref: TM-T70170