CAS 1821666-73-2

Formel: C21H23N7O3S

InChl: InChI=1S/C21H23N7O3S/c1-13-5-6-15(11-19(13)32(22,30)31)24-21-23-10-9-20(25-21)28(4,29)16-7-8-17-14(2)27(3)26-18(17)12-16/h5-12H,1-4H3,(H2,22,30,31)(H,23,24,25)

InChI Key: KIPCSJZOAYPRHI-UHFFFAOYSA-N

SMILES: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)[N+](C)(C3=CC4=NN(C(=C4C=C3)C)C)[O-])S(=O)(=O)N

4-Methyloxidoamino Pazopanib

Kontrolliertes Produkt

CAS: 1821666-73-2

Applications N,2,3-Trimethyl-N-(2-((4-methyl-3-sulfamoylphenyl)amino)pyrimidin-4-yl)-2H-indazol-6-amine oxide is an impurity of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009),

Formel: C₂₁H₂₄N₇O₃S

Farbe und Form: Neat

Molekulargewicht: 454.525

Ref: TR-T798380

Pazopanib Impurity 15

CAS: 1821666-73-2

Formel: C₂₁H₂₃N₇O₃S

Molekulargewicht: 453.5

Ref: ST-EA-CP-P58025