CAS 1849590-01-7

Formel: C17H20N6O2

InChl: InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)

InChI Key: HKTBYUWLRDZAJK-UHFFFAOYSA-N

SMILES: CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3

Tomivosertib

CAS: 1849590-01-7

Tomivosertib

Formel: C₁₇H₂₀N₆O₂

Reinheit: ≥95%

Molekulargewicht: 340.38

Ref: 54-BUP07402

6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione

CAS: 1849590-01-7

Formel: C₁₇H₂₀N₆O₂

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 340.3797

Ref: IN-DA00ABRG

6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione

Kontrolliertes Produkt

CAS: 1849590-01-7

Applications 6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione was used in the study of inhibitors of immune checkpoint modulators and related methods. eFT508 is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor.
References Webster, K., et al.: U.S. Pat. Appl. Publ. (2016), US 20160303124 A1 20161020; Webster, K., et al.: Blood, 126, 1554 (2015);

Formel: C₁₇H₂₀N₆O₂

Farbe und Form: Neat

Molekulargewicht: 340.38

Ref: TR-A629153

eFT508

CAS: 1849590-01-7

eFT508

Formel: C₁₇H₂₀N₆O₂

Reinheit: 98.8% (Typical Value in Batch COA)

Farbe und Form: Solid

Molekulargewicht: 340.37969

Ref: 54-BISN0203

Tomivosertib

CAS: 1849590-01-7

6'-((6-Aminopyrimidin-4-yl)amino)-8'-methyl-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'(2'H)-dione

Formel: C₁₇H₂₀N₆O₂

Reinheit: 98%

Molekulargewicht: 340.38

Ref: IN-DG756354

Tomivosertib

CAS: 1849590-01-7

Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.

Formel: C₁₇H₂₀N₆O₂

Reinheit: 98.42% - 99.72%

Farbe und Form: Solid

Molekulargewicht: 340.3797

Ref: TM-T3468

eFT 508

CAS: 1849590-01-7

Dual inhibitor of MNK1/2 (regulators of mRNA translation)

Formel: C₁₇H₂₀N₆O₂

Reinheit: Min. 95%

Molekulargewicht: 340.38 g/mol

Ref: 3D-BE168437