CAS 1928763-08-9

Formel: C19H24ClN3O3

InChl: InChI=1S/C19H24ClN3O3/c1-12(2)26-19(25)22-14-5-8-23(9-6-14)11-13-10-16(20)15-4-3-7-21-17(15)18(13)24/h3-4,7,10,12,14,24H,5-6,8-9,11H2,1-2H3,(H,22,25)

InChI Key: CWIXCQOSULUGBT-UHFFFAOYSA-N

SMILES: CC(C)OC(=O)NC1CCN(CC1)CC2=CC(=C3C=CC=NC3=C2O)Cl

ML418

CAS: 1928763-08-9

ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.

Formel: C₁₉H₂₄ClN₃O₃

Reinheit: 99.3%

Farbe und Form: Solid

Molekulargewicht: 377.865

Ref: TM-T16110

Isopropyl (1-((5-Chloro-8-Hydroxyquinolin-7-Yl)Methyl)Piperidin-4-Yl)Carbamate

CAS: 1928763-08-9

Isopropyl (1-((5-Chloro-8-Hydroxyquinolin-7-Yl)Methyl)Piperidin-4-Yl)Carbamate

Formel: C₁₉H₂₄ClN₃O₃

Reinheit: 98%

Molekulargewicht: 377.87

Ref: 54-OR1022875

ML418

CAS: 1928763-08-9

ML418

Formel: C₁₉H₂₄ClN₃O₃

Reinheit: 99%

Molekulargewicht: 377.87

Ref: 54-BUP09591

ML418

CAS: 1928763-08-9

Formel: C₁₉H₂₄ClN₃O₃

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 377.8652

Ref: IN-DA01KK2E

Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate

CAS: 1928763-08-9

Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate

Formel: C₁₉H₂₄ClN₃O₃

Reinheit: 98%

Molekulargewicht: 377.87

Ref: IN-DG01171007

Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate

CAS: 1928763-08-9

Reinheit: ≥98%(HPLC)

Molekulargewicht: 377.8699951

Ref: 10-F867799

ML418

CAS: 1928763-08-9

ML418 is a selective melanocortin receptor 4 (MC4) agonist that has been shown to increase muscle contractility in vivo. It is a non-selective ligand that binds to the MC4 receptor with a binding affinity of Kd = 0.1 nM. ML418 has also been observed to produce glutamate release from synaptosomes and increase the amplitude of currents in cultured neurons, which may be due to its ability to activate ionotropic glutamate receptors. The molecular modeling studies suggested that ML418 binds to the extracellular domain of the MC4 receptor and activates signaling pathways mediated by G protein coupled receptors, leading to an increased contractility in skeletal muscle.

Formel: C₁₉H₂₄ClN₃O₃

Reinheit: Min. 95%

Molekulargewicht: 377.87 g/mol

Ref: 3D-DCD76308