CAS 2023788-19-2

Tirzepatid

Beschreibung:

Tirzepatid ist ein neuartiges synthetisches Peptid, das als dualer Agonist für die Rezeptoren des glucagonähnlichen Peptids-1 (GLP-1) und des glucoseabhängigen insulinotropen Polypeptids (GIP) fungiert. Es wird hauptsächlich zur Behandlung von Typ-2-Diabetes und Fettleibigkeit entwickelt. Die Substanz zeichnet sich durch ihre einzigartige Struktur aus, die es ihr ermöglicht, die Insulinsekretion als Reaktion auf Mahlzeiten zu erhöhen, die Glukagonspiegel zu senken und das Sättigungsgefühl zu fördern, wodurch sie zur glykämischen Kontrolle und Gewichtsmanagement beiträgt. Tirzepatid hat eine lange Halbwertszeit, die eine wöchentliche Verabreichung ermöglicht, was die Patientenadhärenz im Vergleich zu täglichen Medikamenten verbessert. Sein Wirkmechanismus besteht darin, die Wirkungen der Inkretinhormone nachzuahmen, was zu einer Verbesserung des Glukosestoffwechsels führt. Klinische Studien haben eine signifikante Wirksamkeit bei der Senkung des Blutzuckerspiegels und der Förderung des Gewichtsverlusts bei Personen mit Typ-2-Diabetes gezeigt. Wie bei jedem Medikament können potenzielle Nebenwirkungen gastrointestinale Probleme umfassen, und es ist wichtig, dass Patienten Gesundheitsfachleute für persönliche Beratung und Überwachung während der Behandlung konsultieren.

Formel: C225H348N48O68

InChl: InChI=1S/C225H348N48O68/c1-23-126(10)183(264-198(311)146(64-50-52-88-226)246-202(315)157(109-180(297)298)252-199(312)152(103-124(6)7)261-223(337)225(21,22)269-217(330)185(128(12)25-3)266-209(322)163(120-278)257-200(313)153(107-138-74-78-141(282)79-75-138)250-203(316)158(110-181(299)300)253-207(320)162(119-277)259-216(329)187(134(18)280)267-206(319)155(106-136-60-44-41-45-61-136)254-215(328)186(133(17)279)262-174(289)114-237-193(306)147(83-87-179(295)296)260-222(336)224(19,20)268-192(305)143(227)104-137-72-76-140(281)77-73-137)214(327)242-131(15)190(303)244-148(80-84-168(228)283)196(309)245-145(65-51-53-89-231-175(290)121-340-100-99-339-97-91-233-176(291)122-341-101-98-338-96-90-232-170(285)86-82-150(221(334)335)243-171(286)70-46-38-36-34-32-30-28-26-27-29-31-33-35-37-39-47-71-178(293)294)195(308)240-130(14)191(304)248-154(105-135-58-42-40-43-59-135)205(318)263-182(125(8)9)212(325)247-149(81-85-169(229)284)197(310)251-156(108-139-111-234-144-63-49-48-62-142(139)144)201(314)249-151(102-123(4)5)204(317)265-184(127(11)24-2)213(326)241-129(13)189(302)236-112-172(287)235-115-177(292)270-92-54-66-164(270)210(323)258-161(118-276)208(321)256-160(117-275)194(307)238-113-173(288)239-132(16)218(331)272-94-56-68-166(272)220(333)273-95-57-69-167(273)219(332)271-93-55-67-165(271)211(324)255-159(116-274)188(230)301/h40-45,48-49,58-63,72-79,111,123-134,143,145-167,182-187,234,274-282H,23-39,46-47,50-57,64-71,80-110,112-122,226-227H2,1-22H3,(H2,228,283)(H2,229,284)(H2,230,301)(H,231,290)(H,232,285)(H,233,291)(H,235,287)(H,236,302)(H,237,306)(H,238,307)(H,239,288)(H,240,308)(H,241,326)(H,242,327)(H,243,286)(H,244,303)(H,245,309)(H,246,315)(H,247,325)(H,248,304)(H,249,314)(H,250,316)(H,251,310)(H,252,312)(H,253,320)(H,254,328)(H,255,324)(H,256,321)(H,257,313)(H,258,323)(H,259,329)(H,260,336)(H,261,337)(H,262,289)(H,263,318)(H,264,311)(H,265,317)(H,266,322)(H,267,319)(H,268,305)(H,269,330)(H,293,294)(H,295,296)(H,297,298)(H,299,300)(H,334,335)/t126-,127-,128-,129-,130-,131-,132-,133+,134+,143-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,182-,183-,184-,185-,186-,187-/m0/s1

InChI Key: BTSOGEDATSQOAF-MCNPHUAVSA-N

SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N4CCC[C@H]4C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N5CCC[C@H]5C(=O)N6CCC[C@H]6C(=O)N7CCC[C@H]7C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](CC8=CC=C(C=C8)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC9=CC=CC=C9)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](CC1=CC=C(C=C1)O)N

Synonyme:

• Tianeptine  Sodium

Tirzepatide

CAS: 2023788-19-2

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Molekulargewicht: 4813.53

Ref: 4Z-PT-453001

Tirzepatide sodium salt

CAS: 2023788-19-2

Formel: C₂₂₅H₃₄₈N₄₈O₆₈·Nax

Reinheit: ≥ 95.0%

Farbe und Form: White to off-white powder or solid

Molekulargewicht: 4813.45 (ex. Na)

Ref: 7W-GP2780

Tirzepatide

CAS: 2023788-19-2

Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Reinheit: 99.52% - 99.99%

Farbe und Form: White Solid

Molekulargewicht: 4813.45

Ref: TM-TP1111

Tirzepatide

CAS: 2023788-19-2

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Farbe und Form: Neat

Molekulargewicht: 4813.45

Ref: TR-T242115

Tirzepatide

CAS: 2023788-19-2

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Reinheit: 99% (sodium salt, contains <5% water)

Molekulargewicht: 4813.45

Ref: IN-DG01130147

Heavy Tirzepatide (+52Da)

CAS: 2023788-19-2

Heavy Tirzepatide (+52Da)

Reinheit: Min. 95%

Molekulargewicht: 4,862.7 g/mol

Ref: 3D-CRB1301725

Tirzepatide

CAS: 2023788-19-2

Cymit Quimica provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Cymit Quimica against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 4,813 g/mol

Ref: 3D-FT181880

Tirzepatide sodium

CAS: 2023788-19-2

Cymit Quimica provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Cymit Quimica against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.

Formel: C₂₂₅H₃₄₈N₄₈O₆₈•xNa

Reinheit: Min. 95 Area-%

Farbe und Form: Powder

Ref: 3D-BT183282

Tirzepatide

CAS: 2023788-19-2

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Molekulargewicht: 4813.5

Ref: ST-EA-CP-T133000

Tirzepatide acetate

CAS: 2023788-19-2

Cymit Quimica provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Cymit Quimica against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.

Reinheit: Min. 95%

Ref: 3D-FT182420

Tirzepatide

CAS: 2023788-19-2

Formel: C₂₂₅H₃₄₈N₄₈O₆₈

Reinheit: 99%

Farbe und Form: Solid

Molekulargewicht: 4813.4514

Ref: IN-DA01MVDA